TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T86385	Cathepsin G	B3S4MT	6-Chlorooxindole	Investigative	736344	C8H6ClNO	167.59	C1C2=C(C=C(C=C2)Cl)NC1=O	IC50 > 1000000 nM	Non binder
T86385	Cathepsin G	B47MNT	5,5-Dimethyl-3-(4-methylphenyl)sulfonyl-1,3-oxazolidine-2,4-dione	Investigative	66561877	C12H13NO5S	283.3	CC1=CC=C(C=C1)S(=O)(=O)N2C(=O)C(OC2=O)(C)C	IC50 = 369000 nM	Non binder
T86385	Cathepsin G	B49SJD	N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(2-fluoro-phenyl)-propionamide	Investigative	10383086	C19H19ClFNO2	347.8	C1=CC=C(C=C1)C[C@@H](C(=O)CCl)NC(=O)CCC2=CC=CC=C2F	IC50 > 1000000 nM	Non binder
T86385	Cathepsin G	B4EP5G	2,2',4-Trihydroxybenzophenone	Investigative	578663	C13H10O4	230.22	C1=CC=C(C(=C1)C(=O)C2=C(C=C(C=C2)O)O)O	IC50 = 433200 nM	Non binder
T86385	Cathepsin G	B7P0SL	4-N-[(2S)-3-Methyl-1-oxo-1-[(2S)-2-[(5,5,6,6,6-pentafluoro-2-methyl-4-oxohexan-3-yl)carbamoyl]pyrrolidin-1-yl]butan-2-yl]-1-N-(4,4,4-trifluoro-3-oxo-1-phenylbutan-2-yl)benzene-1,4-dicarboxamide	Investigative	44366665	C35H38F8N4O6	762.7	CC(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)NC(C(C)C)C(=O)C(C(F)(F)F)(F)F)NC(=O)C2=CC=C(C=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)C(F)(F)F	Ki > 1000000 nM	Non binder
T86385	Cathepsin G	BB12OY	Methyl 2-(3-benzamido-3-benzyl-2-oxoazetidin-1-yl)acetate	Investigative	10383359	C20H20N2O4	352.4	COC(=O)CN1CC(C1=O)(CC2=CC=CC=C2)NC(=O)C3=CC=CC=C3	Ki = 400000 nM	Non binder
T86385	Cathepsin G	BI8U7T	N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(3-fluoro-phenyl)-propionamide	Investigative	44303533	C19H19ClFNO2	347.8	C1=CC=C(C=C1)C[C@@H](C(=O)CCl)NC(=O)CCC2=CC(=CC=C2)F	IC50 = 890000 nM	Non binder
T86385	Cathepsin G	BJ1U8N	4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride	Investigative	186136	C8H11ClFNO2S	239.7	C1=CC(=CC=C1CCN)S(=O)(=O)F.Cl	IC50 = 250000 nM	Non binder
T86385	Cathepsin G	BRA48V	(S)-1-(((5-(Dimethylamino)naphthalen-1-yl)sulfonyl)-L-alanyl-L-alanyl)-N-((S)-1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)pyrrolidine-2-carboxamide	Investigative	9917430	C29H38F3N5O6S	641.7	C[C@@H](C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F)NS(=O)(=O)C2=CC=CC3=C2C=CC=C3N(C)C	Ki > 600000 nM	Non binder
T86385	Cathepsin G	BSHE36	N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(3-methoxy-phenyl)-propionamide	Investigative	44303216	C20H22ClNO3	359.8	COC1=CC=CC(=C1)CCC(=O)N[C@@H](CC2=CC=CC=C2)C(=O)CCl	IC50 = 210000 nM	Non binder
T86385	Cathepsin G	BW90AR	(S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-decanoylamino]-3-phenyl-propionic acid ethyl ester	Investigative	10577862	C31H41N3O4	519.7	CCCCCCCC(C(C)(C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)OCC)NC(=O)C2=CC=C(C=C2)C#N	IC50 = 440000 nM	Non binder
T86385	Cathepsin G	BWF0I1	2-{(S)-2-[((S)-1-{(S)-2-[4-(4-Chloro-benzenesulfonylaminocarbonyl)-benzoylamino]-3-methyl-butyryl}-pyrrolidine-2-carbonyl)-amino]-3-methyl-butyryl}-benzooxazole-5-carboxylic acid amide	Investigative	9962331	C37H39ClN6O9S	779.3	CC(C)[C@@H](C(=O)C1=NC2=C(O1)C=CC(=C2)C(=O)N)NC(=O)[C@@H]3CCCN3C(=O)[C@H](C(C)C)NC(=O)C4=CC=C(C=C4)C(=O)NS(=O)(=O)C5=CC=C(C=C5)Cl	Ki > 2000000 nM	Non binder
T86385	Cathepsin G	D0E9EH	Acetyl-Ala-Ala-Pro-Ala-trifluromethane	Investigative	44353386	C17H25F3N4O5	422.4	C[C@@H](C(=O)C(F)(F)F)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)C	Ki > 800000 nM	Non binder