TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T92517	Calpain-1	B1ZCH3	N-[4-(Ethylamino)-3,4-dioxo-1-phenylbutan-2-yl]-1-naphthalen-2-ylsulfonylpiperidine-4-carboxamide	Investigative	44309687	C28H31N3O5S	521.6	CCNC(=O)C(=O)C(CC1=CC=CC=C1)NC(=O)C2CCN(CC2)S(=O)(=O)C3=CC4=CC=CC=C4C=C3	Ki = 800000 nM	Non binder
T92517	Calpain-1	B2ILB8	[(S)-1-((R)-1-Benzyl-2-ethylcarbamoyl-2-hydroxy-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester	Investigative	44330979	C26H35N3O5	469.6	CCNC(=O)C([C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(C)C)NC(=O)OCC2=CC=CC=C2)O	Ki > 350000 nM	Non binder
T92517	Calpain-1	B9WU4C	N-(4-Fluorophenylsulfonyl)-D-valyl-D-leucinal	Investigative	11122265	C17H25FN2O4S	372.5	CC(C)C[C@H](C=O)NC(=O)[C@@H](C(C)C)NS(=O)(=O)C1=CC=C(C=C1)F	IC50 = 1000000 nM	Non binder
T92517	Calpain-1	BNVG37	[2-[(E)-[2-Methylpropyl-[2-[2-methylpropyl(phenylmethoxycarbonylamino)amino]-2-oxoethyl]hydrazinylidene]methyl]phenyl]boronic acid	Investigative	11237019	C25H35BN4O5	482.4	B(C1=CC=CC=C1/C=N/N(CC(C)C)CC(=O)N(CC(C)C)NC(=O)OCC2=CC=CC=C2)(O)O	IC50 > 1000000 nM	Non binder
T92517	Calpain-1	BVCT19	[3-[(E)-[Benzyl-[2-[2-methylpropyl(phenylmethoxycarbonylamino)amino]-2-oxoethyl]hydrazinylidene]methyl]phenyl]boronic acid	Investigative	11432299	C28H33BN4O5	516.4	B(C1=CC(=CC=C1)/C=N/N(CC2=CC=CC=C2)CC(=O)N(CC(C)C)NC(=O)OCC3=CC=CC=C3)(O)O	IC50 > 1000000 nM	Non binder