TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T92828	Endothelin B receptor	B5LPA4	N-(3,4-Dimethyl-isoxazol-5-yl)-2-thiophen-2-yl-benzenesulfonamide	Investigative	9927658	C15H14N2O3S2	334.4	CC1=C(ON=C1C)NS(=O)(=O)C2=CC=CC=C2C3=CC=CS3	Ki > 200000 nM	Non binder
T92828	Endothelin B receptor	B6M9DI	(5S,6R,7R)-5-(3,4-Dimethoxyphenyl)-4-methoxy-6,7-bis(methoxymethyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole	Investigative	10477792	C24H30O7	430.5	COC[C@@H]1CC2=CC3=C(C(=C2[C@@H]([C@H]1COC)C4=CC(=C(C=C4)OC)OC)OC)OCO3	IC50 > 500000 nM	Non binder
T92828	Endothelin B receptor	B6NF8G	N-(3,4-Dimethyl-isoxazol-5-yl)-2-thiophen-3-yl-benzenesulfonamide	Investigative	9840650	C15H14N2O3S2	334.4	CC1=C(ON=C1C)NS(=O)(=O)C2=CC=CC=C2C3=CSC=C3	Ki > 200000 nM	Non binder
T92828	Endothelin B receptor	B8TZ5R	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid methyl ester	Investigative	9820754	C23H17NO4	371.4	COC(=O)C(C1=CC2=C(C=C1)OCO2)C3=C4C=CC=CC4=NC5=CC=CC=C53	IC50 > 250000 nM	Non binder
T92828	Endothelin B receptor	BD5S2P	3-[(4-Chloro-3-methyl-1,2-oxazol-5-yl)sulfamoyl]-N-(4-methyl-1,3-benzodioxol-5-yl)thiophene-2-carboxamide	Investigative	44291255	C17H14ClN3O6S2	455.9	CC1=C(C=CC2=C1OCO2)NC(=O)C3=C(C=CS3)S(=O)(=O)NC4=C(C(=NO4)C)Cl	IC50 = 355500 nM	Non binder
T92828	Endothelin B receptor	BF6XD2	N-(3,4-Dimethyl-isoxazol-5-yl)-2-pyrimidin-2-yl-benzenesulfonamide	Investigative	9818889	C15H14N4O3S	330.4	CC1=C(ON=C1C)NS(=O)(=O)C2=CC=CC=C2C3=NC=CC=N3	Ki > 200000 nM	Non binder
T92828	Endothelin B receptor	BGR40K	4-[(2R,3R)-3-[(3,4-Dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-1,2-dimethoxybenzene	Investigative	9953821	C24H34O6	418.5	COC[C@H](CC1=CC(=C(C=C1)OC)OC)[C@@H](CC2=CC(=C(C=C2)OC)OC)COC	IC50 > 500000 nM	Non binder
T92828	Endothelin B receptor	BK92PQ	3-Benzo[1,3]dioxol-5-yl-5-ethoxy-1-(4-methoxy-benzyl)-1H-indole-2-carboxylic acid	Investigative	44298982	C26H23NO6	445.5	CCOC1=CC2=C(C=C1)N(C(=C2C3=CC4=C(C=C3)OCO4)C(=O)O)CC5=CC=C(C=C5)OC	IC50 = 300000 nM	Non binder
T92828	Endothelin B receptor	BTQ74V	N-(3,4-Dimethyl-5-isoxazolyl)-4'-(1H-tetrazole-5-yl)biphenyl-2-sulfonamide	Investigative	44365878	C18H16N6O3S	396.4	CC1=C(ON=C1C)NS(=O)(=O)C2=CC=CC=C2C3=CC=C(C=C3)C4=NNN=N4	Ki > 200000 nM	Non binder
T92828	Endothelin B receptor	BYU1O7	Hypophyllanthin	Investigative	182140	C24H30O7	430.5	COC[C@@H]1CC2=CC(=C3C(=C2[C@@H]([C@H]1COC)C4=CC(=C(C=C4)OC)OC)OCO3)OC	IC50 > 500000 nM	Non binder
T92828	Endothelin B receptor	BZ1A7S	N-(3,4-Dimethyl-isoxazol-5-yl)-2-(1H-indol-3-yl)-benzenesulfonamide	Investigative	9799352	C19H17N3O3S	367.4	CC1=C(ON=C1C)NS(=O)(=O)C2=CC=CC=C2C3=CNC4=CC=CC=C43	Ki > 200000 nM	Non binder
T92828	Endothelin B receptor	BZU10T	N-(3,4-Dimethyl-isoxazol-5-yl)-2-pyridin-3-yl-benzenesulfonamide	Investigative	9797546	C16H15N3O3S	329.4	CC1=C(ON=C1C)NS(=O)(=O)C2=CC=CC=C2C3=CN=CC=C3	Ki > 200000 nM	Non binder