TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T94479	Ribosomal protein S6 kinase beta-1	B1SK6J	1-(5-Tert-butyl-3-(morpholine-4-carbonyl)thiophen-2-yl)-3-(1H-indazol-5-yl)urea	Investigative	53319169	C21H25N5O3S	427.5	CC(C)(C)C1=CC(=C(S1)NC(=O)NC2=CC3=C(C=C2)NN=C3)C(=O)N4CCOCC4	IC50 = 207000 nM	Non binder
T94479	Ribosomal protein S6 kinase beta-1	B57VRQ	N-[2-(Dimethylamino)ethyl]-2-(1H-indazol-5-ylcarbamoylamino)-5-methylthiophene-3-carboxamide	Investigative	53325333	C18H22N6O2S	386.5	CC1=CC(=C(S1)NC(=O)NC2=CC3=C(C=C2)NN=C3)C(=O)NCCN(C)C	IC50 = 223000 nM	Non binder
T94479	Ribosomal protein S6 kinase beta-1	B6RQO9	2-(3-1H-Indazol-5-ylureido)-N-benzyl-5-tert-butylthiophene-3-carboxamide	Investigative	53320486	C24H25N5O2S	447.6	CC(C)(C)C1=CC(=C(S1)NC(=O)NC2=CC3=C(C=C2)NN=C3)C(=O)NCC4=CC=CC=C4	IC50 = 201000 nM	Non binder
T94479	Ribosomal protein S6 kinase beta-1	BMF4W3	N-[2-(Dimethylamino)ethyl]-5-[(1S)-1-hydroxyethyl]-2-(1H-indazol-5-ylcarbamoylamino)thiophene-3-carboxamide	Investigative	53317852	C19H24N6O3S	416.5	C[C@@H](C1=CC(=C(S1)NC(=O)NC2=CC3=C(C=C2)NN=C3)C(=O)NCCN(C)C)O	IC50 = 379000 nM	Non binder
T94479	Ribosomal protein S6 kinase beta-1	BU8CL4	N-[2-(Dimethylamino)ethyl]-2-(1H-indazol-5-ylcarbamoylamino)-5-phenylthiophene-3-carboxamide	Investigative	53320540	C23H24N6O2S	448.5	CN(C)CCNC(=O)C1=C(SC(=C1)C2=CC=CC=C2)NC(=O)NC3=CC4=C(C=C3)NN=C4	IC50 = 1900000 nM	Non binder