TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T97071	Glutamate carboxypeptidase II	D00ENY	L-Glutamic Acid	Approved	33032	C5H9NO4	147.13	C(CC(=O)O)[C@@H](C(=O)O)N	IC50 = 428000 nM	Non binder
T97071	Glutamate carboxypeptidase II	B06JBR	(S)-3-(2-Carboxy-2-(3-(1-methoxy-4-methyl-1-oxopentan-2-yl)ureido)ethyl)benzoic acid	Investigative	46227570	C18H24N2O7	380.4	CC(C)C[C@@H](C(=O)OC)NC(=O)N[C@@H](CC1=CC(=CC=C1)C(=O)O)C(=O)O	Ki > 1000000 nM	Non binder
T97071	Glutamate carboxypeptidase II	B0RP8W	(S)-2-(3-((S)-1-Methoxy-4-methyl-1-oxopentan-2-yl)ureido)-4-(methylthio)butanoic acid	Investigative	46227590	C14H26N2O5S	334.43	CC(C)C[C@@H](C(=O)OC)NC(=O)N[C@@H](CCCSC)C(=O)O	Ki > 1000000 nM	Non binder
T97071	Glutamate carboxypeptidase II	B2VSX4	(S)-3-(3-Hydroxyphenyl)-2-(3-(1-methoxy-4-methyl-1-oxopentan-2-yl)ureido)propanoic acid	Investigative	46227560	C17H24N2O6	352.4	CC(C)C[C@@H](C(=O)OC)NC(=O)N[C@@H](CC1=CC(=CC=C1)O)C(=O)O	Ki > 1000000 nM	Non binder
T97071	Glutamate carboxypeptidase II	B3ADQ6	L-Serine O-sulfate	Investigative	164701	C3H7NO6S	185.16	C([C@@H](C(=O)O)N)OS(=O)(=O)O	IC50 = 438000 nM	Non binder
T97071	Glutamate carboxypeptidase II	B5A1LZ	(S)-2-(3-((S)-1-Carboxy-2-(1H-indol-3-yl)ethyl)ureido)-4-methylpentanoic acid	Investigative	46227602	C20H27N3O5	389.4	CC(C)C[C@@H](C(=O)OC)NC(=O)N[C@@H](CCC1=CNC2=CC=CC=C21)C(=O)O	Ki > 1000000 nM	Non binder
T97071	Glutamate carboxypeptidase II	B5JM4O	(2S)-2-[[[(3S,5R)-1-[(4S)-4-Amino-4-carboxybutanoyl]-5-carboxypyrrolidin-3-yl]oxy-hydroxyphosphoryl]amino]pentanedioic acid	Investigative	118737811	C15H24N3O12P	469.34	C1[C@@H](CN([C@H]1C(=O)O)C(=O)CC[C@@H](C(=O)O)N)OP(=O)(N[C@@H](CCC(=O)O)C(=O)O)O	IC50 = 357000 nM	Non binder
T97071	Glutamate carboxypeptidase II	BJ0SN6	(S)-2-(3-Hydroxyphenyl)-2-(3-(1-methoxy-4-methyl-1-oxopentan-2-yl)ureido)acetic acid	Investigative	46227629	C16H22N2O6	338.36	CC(C)C[C@@H](C(=O)OC)NC(=O)NC(C1=CC(=CC=C1)O)C(=O)O	Ki > 1000000 nM	Non binder
T97071	Glutamate carboxypeptidase II	BXHE51	(S)-2-(3-(Carboxy(3-hydroxyphenyl)methyl)ureido)-4-methylpentanoic acid	Investigative	46227568	C15H20N2O6	324.33	CC(C)C[C@@H](C(=O)O)NC(=O)NC(C1=CC(=CC=C1)O)C(=O)O	Ki > 1000000 nM	Non binder
T97071	Glutamate carboxypeptidase II	BYC12S	(S)-2-(4-Fluoro-3-methoxyphenyl)-2-(3-(1-methoxy-4-methyl-1-oxopentan-2-yl)ureido)acetic acid	Investigative	46227618	C17H23FN2O6	370.4	CC(C)C[C@@H](C(=O)OC)NC(=O)NC(C1=CC(=C(C=C1)F)OC)C(=O)O	Ki > 1000000 nM	Non binder
T97071	Glutamate carboxypeptidase II	D07PZQ	L-serine-O-phosphate	Investigative	68841	C3H8NO6P	185.07	C([C@@H](C(=O)O)N)OP(=O)(O)O	IC50 = 523000 nM	Non binder