TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T00663	Stress-activated protein kinase JNK3	B19QVJ	4-(5-(Naphthalen-2-yl)-1H-tetrazol-1-yl)pyridine	Investigative	54581363	C16H11N5	273.29	C1=CC=C2C=C(C=CC2=C1)C3=NN=NN3C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	B2QYF7	Methyl 5-(2-(naphthalen-1-yl)acetamido)-1,2,3-thiadiazole-4-carboxylate	Investigative	52947399	C16H13N3O3S	327.4	COC(=O)C1=C(SN=N1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	B4TK6V	N-(4-Methylpyridin-3-yl)-2-(naphthalen-1-yl)acetamide	Investigative	52944962	C18H16N2O	276.3	CC1=C(C=NC=C1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	B4ZA2H	3-(2-Methylpyridin-4-yl)-4-(quinolin-3-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54585286	C17H13N5S	319.4	CC1=NC=CC(=C1)C2=NNC(=S)N2C3=CC4=CC=CC=C4N=C3	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	B69XRH	Methyl 4-(2-(naphthalen-1-yl)acetamido)thiazole-5-carboxylate	Investigative	52947421	C17H14N2O3S	326.4	COC(=O)C1=C(N=CS1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	B7MO4E	4-[6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl]-N-[2-(dimethylamino)ethyl]benzamide	Investigative	24959046	C21H26N6O	378.5	CN(C)CCNC(=O)C1=CC=C(C=C1)C2=CN=C3N2N=C(C=C3)NCC4CC4	IC50 ~ 100000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	B7O8WI	Ethyl 3-methyl-5-(2-(naphthalen-1-yl)acetamido)isothiazole-4-carboxylate	Investigative	52946172	C19H18N2O3S	354.4	CCOC(=O)C1=C(SN=C1C)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BCZ2E3	3-(Pyridin-4-yl)-4-(quinolin-3-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54581359	C16H11N5S	305.4	C1=CC=C2C(=C1)C=C(C=N2)N3C(=NNC3=S)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BD3C7X	N-(3-Methylpyrazin-2-yl)-2-(naphthalen-1-yl)acetamide	Investigative	52949737	C17H15N3O	277.32	CC1=NC=CN=C1NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BI91UH	4-(4-(Naphthalen-2-yl)-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl)pyridine	Investigative	54585289	C18H11F3N4	340.3	C1=CC=C2C=C(C=CC2=C1)N3C(=NN=C3C(F)(F)F)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BP3CX9	Methyl 2-(2-(naphthalen-1-yl)acetamido)nicotinate	Investigative	52947422	C19H16N2O3	320.3	COC(=O)C1=C(N=CC=C1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BPO9D8	4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-(2-pyrrolidin-1-ylethyl)benzamide	Investigative	49864785	C26H26Cl2N6O	509.4	C1CCN(C1)CCNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5=CC(=C(C=C5)Cl)Cl	IC50 = 90000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BQ50VT	N-(2-(Hydroxymethyl)thiophen-3-yl)-2-phenylacetamide	Investigative	52943427	C13H13NO2S	247.31	C1=CC=C(C=C1)CC(=O)NC2=C(SC=C2)CO	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BQUZ09	4-[6-[(3-Chlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[[(2S)-pyrrolidin-2-yl]methyl]benzamide	Investigative	49865153	C25H25ClN6O	461	C1C[C@H](NC1)CNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5=CC(=CC=C5)Cl	IC50 = 78000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BRDF65	Methyl 4-(2-(naphthalen-1-yl)acetamido)-1,2,5-oxadiazole-3-carboxylate	Investigative	52942532	C16H13N3O4	311.29	COC(=O)C1=NON=C1NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BRJ6O8	2-Phenyl-N-(2-(prop-1-en-2-yl)thiophen-3-yl)acetamide	Investigative	52942227	C15H15NOS	257.399	CC(=C)C1=C(C=CS1)NC(=O)CC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BVDF78	(S)-4-(6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(pyrrolidin-2-ylmethyl)benzamide	Investigative	46933384	C22H26N6O	390.5	C1C[C@H](NC1)CNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5CC5	IC50 ~ 100000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BWY3P1	4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[[(2S)-pyrrolidin-2-yl]methyl]benzamide	Investigative	49864850	C25H24Cl2N6O	495.4	C1C[C@H](NC1)CNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5=CC(=C(C=C5)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BX68VA	N-(2-Methoxyethyl)-N-methyl-3-(2-phenylacetamido)thiophene-2-carboxamide	Investigative	52948602	C17H20N2O3S	332.4	CN(CCOC)C(=O)C1=C(C=CS1)NC(=O)CC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T00663	Stress-activated protein kinase JNK3	BZ21PQ	3-(2-Bromopyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54585287	C17H11BrN4S	383.3	C1=CC=C2C=C(C=CC2=C1)N3C(=NNC3=S)C4=CC(=NC=C4)Br	IC50 ~ 50000 nM	Poor binder