TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T04689	Neuronal acetylcholine receptor alpha-1	D0T8GD	Nicotine	Approved	89594	C10H14N2	162.23	CN1CCC[C@H]1C2=CN=CC=C2	EC50 = 180000 nM	Poor binder
T04689	Neuronal acetylcholine receptor alpha-1	B5HFI2	2-((S)-1-Methyl-pyrrolidin-2-yl)-furo[3,2-b]pyridine	Investigative	9882021	C12H14N2O	202.25	CN1CCC[C@H]1C2=CC3=C(O2)C=CC=N3	EC50 ~ 100000 nM	Poor binder
T04689	Neuronal acetylcholine receptor alpha-1	BP10FV	Thiacloprid	Investigative	115224	C10H9ClN4S	252.72	C1CSC(=NC#N)N1CC2=CN=C(C=C2)Cl	IC50 = 120000 nM	Poor binder
T04689	Neuronal acetylcholine receptor alpha-1	BQ2JU3	Hexahydropyrimidine2nitromethylene16chloro3pyrid	Investigative	21290600	C11H13ClN4O2	268.7	C1CN/C(=C/[N+](=O)[O-])/N(C1)CC2=CN=C(C=C2)Cl	IC50 = 81000 nM	Poor binder