TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T04831	Tyrosine-protein kinase EIF2AK2	B5HV9E	4-(2-Phenyl-1H-indol-3-yl)-N-(pyridin-3-ylmethyl)pyrimidin-2-amine	Investigative	56679961	C24H19N5	377.4	C1=CC=C(C=C1)C2=C(C3=CC=CC=C3N2)C4=NC(=NC=C4)NCC5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	B5MJU8	4-(5-Methoxy-1H-indol-3-yl)-N-(2-morpholin-4-ylethyl)pyrimidin-2-amine	Investigative	56659462	C19H23N5O2	353.4	COC1=CC2=C(C=C1)NC=C2C3=NC(=NC=C3)NCCN4CCOCC4	IC50 ~ 100000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	B6R0UT	2-Methyl-3-[2-(4-pyridin-2-ylpiperazin-1-yl)pyrimidin-4-yl]-1H-indole	Investigative	56676675	C22H22N6	370.4	CC1=C(C2=CC=CC=C2N1)C3=NC(=NC=C3)N4CCN(CC4)C5=CC=CC=N5	IC50 ~ 100000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BA02JS	4-(5-Methoxy-2-methyl-1H-indol-3-yl)-N-(4-methoxyphenyl)pyrimidin-2-amine	Investigative	56673297	C21H20N4O2	360.4	CC1=C(C2=C(N1)C=CC(=C2)OC)C3=NC(=NC=C3)NC4=CC=C(C=C4)OC	IC50 = 55000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BBT7K3	N-Cyclopentyl-4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-amine	Investigative	56659460	C23H22N4	354.4	C1CCC(C1)NC2=NC=CC(=N2)C3=C(NC4=CC=CC=C43)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BC5S9G	3-Methyl-2-[[4-(2-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino]butan-1-ol	Investigative	56669853	C18H22N4O	310.4	CC1=C(C2=CC=CC=C2N1)C3=NC(=NC=C3)NC(CO)C(C)C	IC50 = 50000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BG23LO	3-[2-[4-(4-Fluorophenyl)piperazin-1-yl]pyrimidin-4-yl]-2-methyl-1H-indole	Investigative	56666438	C23H22FN5	387.5	CC1=C(C2=CC=CC=C2N1)C3=NC(=NC=C3)N4CCN(CC4)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BHU84C	N-[2-(1H-Indol-3-yl)ethyl]-4-(5-pyridin-4-yl-1H-pyrazol-4-yl)pyrimidin-2-amine	Investigative	56676624	C22H19N7	381.4	C1=CC=C2C(=C1)C(=CN2)CCNC3=NC=CC(=N3)C4=C(NN=C4)C5=CC=NC=C5	IC50 = 51000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BJ8K3U	3-[2-[4-(4-Fluorophenyl)piperazin-1-yl]pyrimidin-4-yl]-1H-indole	Investigative	56683289	C22H20FN5	373.4	C1CN(CCN1C2=CC=C(C=C2)F)C3=NC=CC(=N3)C4=CNC5=CC=CC=C54	IC50 ~ 100000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BKQ4J2	5-Chloro-2-methyl-3-(2-pyrrolidin-1-ylpyrimidin-4-yl)-1H-indole	Investigative	56683286	C17H17ClN4	312.8	CC1=C(C2=C(N1)C=CC(=C2)Cl)C3=NC(=NC=C3)N4CCCC4	IC50 ~ 100000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BM8FJ0	5-Chloro-3-[2-[4-(4-fluorophenyl)piperazin-1-yl]pyrimidin-4-yl]-2-methyl-1H-indole	Investigative	56662962	C23H21ClFN5	421.9	CC1=C(C2=C(N1)C=CC(=C2)Cl)C3=NC(=NC=C3)N4CCN(CC4)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BOJ20C	2-Methyl-3-(2-pyrrolidin-1-ylpyrimidin-4-yl)-1H-indole	Investigative	56683334	C17H18N4	278.35	CC1=C(C2=CC=CC=C2N1)C3=NC(=NC=C3)N4CCCC4	IC50 ~ 100000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BPRB18	N-(4-Chlorophenyl)-4-(5-methoxy-2-methyl-1H-indol-3-yl)pyrimidin-2-amine	Investigative	56683288	C20H17ClN4O	364.8	CC1=C(C2=C(N1)C=CC(=C2)OC)C3=NC(=NC=C3)NC4=CC=C(C=C4)Cl	IC50 = 50000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BX96OQ	4-[4-(2-Methyl-1H-indol-3-yl)pyrimidin-2-yl]morpholine	Investigative	56659514	C17H18N4O	294.35	CC1=C(C2=CC=CC=C2N1)C3=NC(=NC=C3)N4CCOCC4	IC50 = 90000 nM	Poor binder
T04831	Tyrosine-protein kinase EIF2AK2	BY86EO	Methyl 3-[2-[2-(dimethylamino)ethylsulfanyl]pyrimidin-4-yl]-1H-indole-6-carboxylate	Investigative	56659516	C18H20N4O2S	356.4	CN(C)CCSC1=NC=CC(=N1)C2=CNC3=C2C=CC(=C3)C(=O)OC	IC50 ~ 100000 nM	Poor binder