TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T07303	Vascular endothelial growth factor receptor 3	B0RC8P	2-(2-(2-(2-((4-(1-Methylpiperidin-4-yl)-2-(trifluoromethoxy)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)phenyl)acetamide	Investigative	60162249	C28H29F6N5O2	581.6	CN1CCC(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)CCC4=CC=CC=C4CC(=O)N)C(F)(F)F)OC(F)(F)F	IC50 = 59763 nM	Poor binder
T07303	Vascular endothelial growth factor receptor 3	B1CT9I	(4S,6R,12E)-6-Chloro-18-hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dione	Investigative	49842669	C19H23ClO5	366.8	C[C@H]1C[C@H](CC(=O)CCC/C=C/C2=C(C(=CC(=C2)OC)O)C(=O)O1)Cl	IC50 ~ 100000 nM	Poor binder
T07303	Vascular endothelial growth factor receptor 3	B57BWQ	4-(2-Methoxyethyl)phenol	Investigative	92516	C9H12O2	152.19	COCCC1=CC=C(C=C1)O	IC50 ~ 50000 nM	Poor binder
T07303	Vascular endothelial growth factor receptor 3	B5KD4L	(2S)-1-(1H-Indol-3-yl)-3-(5-isoquinolin-6-ylpyridin-3-yl)oxy-propan-2-amine	Investigative	6914611	C25H22N4O	394.5	C1=CC=C2C(=C1)C(=CN2)C[C@@H](COC3=CN=CC(=C3)C4=CC5=C(C=C4)C=NC=C5)N	IC50 ~ 50000 nM	Poor binder
T07303	Vascular endothelial growth factor receptor 3	B97RPS	Serotonin hydrochloride	Investigative	160436	C10H13ClN2O	212.67	C1=CC2=C(C=C1O)C(=CN2)CCN.Cl	IC50 ~ 50000 nM	Poor binder
T07303	Vascular endothelial growth factor receptor 3	BBT3H8	2-(2-(2-(2-((4-(Piperidin-4-yl)-2-(trifluoromethoxy)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)phenyl)acetamide	Investigative	86675848	C27H27F6N5O2	567.5	C1CNCCC1C2=CC(=C(C=C2)NC3=NC=C(C(=N3)CCC4=CC=CC=C4CC(=O)N)C(F)(F)F)OC(F)(F)F	IC50 ~ 66000 nM	Poor binder
T07303	Vascular endothelial growth factor receptor 3	BJ1HE9	(4S,6R,12Z)-6-Chloro-18-hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dione	Investigative	53324892	C19H23ClO5	366.8	C[C@H]1C[C@H](CC(=O)CCC/C=C\\C2=C(C(=CC(=C2)OC)O)C(=O)O1)Cl	IC50 ~ 100000 nM	Poor binder
T07303	Vascular endothelial growth factor receptor 3	BKSR53	(4S,6R,12Z)-6-Bromo-18-hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dione	Investigative	53320915	C19H23BrO5	411.3	C[C@H]1C[C@H](CC(=O)CCC/C=C\\C2=C(C(=CC(=C2)OC)O)C(=O)O1)Br	IC50 = 65000 nM	Poor binder
T07303	Vascular endothelial growth factor receptor 3	BU3CK2	Tert-Butyl-2-{5-(4-hydroxyphenethoxy)-1-{5-[4-(methylthio)phenyl]pentyl}-1H-indole-3-yl}ethyl carbamate	Investigative	46888666	C35H44N2O4S	588.8	CC(C)(C)OC(=O)NCCC1=CN(C2=C1C=C(C=C2)OCCC3=CC=C(C=C3)O)CCCCCC4=CC=C(C=C4)SC	IC50 ~ 50000 nM	Poor binder
T07303	Vascular endothelial growth factor receptor 3	BUBK49	(1S)-2-(1H-Indol-3-YL)-1-[({5-[(E)-2-pyridin-4-ylvinyl]pyridin-3-YL}oxy)methyl]ethylamine	Investigative	6914613	C23H22N4O	370.4	C1=CC=C2C(=C1)C(=CN2)C[C@@H](COC3=CN=CC(=C3)/C=C/C4=CC=NC=C4)N	IC50 ~ 50000 nM	Poor binder