TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T09130	Muscarinic acetylcholine receptor	D0O2WB	Pyridostigmine	Approved	4991	C9H13N2O2+	181.21	C[N+]1=CC=CC(=C1)OC(=O)N(C)C	Ki ~ 100000 nM	Poor binder
T09130	Muscarinic acetylcholine receptor	B2ZV7A	3-[(E)-But-2-enoxy]-4,5,6,7-tetrahydro-[1,2]oxazolo[4,5-c]pyridine;hydrochloride	Investigative	13621558	C10H15ClN2O2	230.69	C/C=C/COC1=NOC2=C1CNCC2.Cl	IC50 ~ 50000 nM	Poor binder
T09130	Muscarinic acetylcholine receptor	B83CKS	2,2-Diphenylpropionic acid (3-hydroxy-2-pyridyl)methyl ester	Investigative	11034977	C21H19NO3	333.4	CC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)OCC3=C(C=CC=N3)O	Ki = 75000.1 nM	Poor binder
T09130	Muscarinic acetylcholine receptor	BBS6Q0	4,5,6,7-Tetrahydro-[1,2]oxazolo[4,5-c]pyridin-3-one;hydrobromide	Investigative	13621534	C6H9BrN2O2	221.05	C1CNCC2=C1ONC2=O.Br	IC50 ~ 50000 nM	Poor binder
T09130	Muscarinic acetylcholine receptor	BEHS61	5-Benzyl-3-methoxy-6,7-dihydro-4H-[1,2]oxazolo[4,5-c]pyridine;hydrochloride	Investigative	13621575	C14H17ClN2O2	280.75	COC1=NOC2=C1CN(CC2)CC3=CC=CC=C3.Cl	IC50 ~ 50000 nM	Poor binder
T09130	Muscarinic acetylcholine receptor	BS7A1R	3-(3-Furyl)quinuclidin-3-ol	Investigative	15196231	C11H15NO2	193.24	C1CN2CCC1C(C2)(C3=COC=C3)O	Ki ~ 58000 nM	Poor binder
T09130	Muscarinic acetylcholine receptor	BT27ZL	[2-(Hydroxymethyl)-1-methylpyridin-1-ium-3-yl] N,N-dimethylcarbamate;iodide	Investigative	10903857	C10H15IN2O3	338.14	C[N+]1=CC=CC(=C1CO)OC(=O)N(C)C.[I-]	Ki ~ 100000 nM	Poor binder
T09130	Muscarinic acetylcholine receptor	BTFJ39	3-Butoxy-4,5,6,7-tetrahydro-[1,2]oxazolo[4,5-c]pyridine;hydrochloride	Investigative	13621550	C10H17ClN2O2	232.71	CCCCOC1=NOC2=C1CNCC2.Cl	IC50 ~ 50000 nM	Poor binder