TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T09572	Melanin-concentrating hormone receptor 1	B1R6CL	N-[2-(Diethylamino)ethyl]-2-methoxy-4-[2-oxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]benzamide	Investigative	44395013	C29H34N4O4	502.6	CCN(CC)CCNC(=O)C1=C(C=C(C=C1)N2CCN(C2=O)C3=CC=C(C=C3)OC4=CC=CC=C4)OC	IC50 ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	B3JK9M	N-(2-Diethylamino-ethyl)-2-methoxy-4-(3-phenyl-ureido)-benzamide	Investigative	44395008	C21H28N4O3	384.5	CCN(CC)CCNC(=O)C1=C(C=C(C=C1)NC(=O)NC2=CC=CC=C2)OC	IC50 ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	B56YFM	N-(2-Diethylamino-ethyl)-2-methoxy-N-methyl-4-[3-(4-phenoxy-phenyl)-ureido]-benzamide	Investigative	44395000	C28H34N4O4	490.6	CCN(CC)CCN(C)C(=O)C1=C(C=C(C=C1)NC(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	B9PXZ5	3,5-Dimethoxy-N-(2,2,6,6-tetramethyl-1-(naphthalen-2-ylmethyl)piperidin-4-yl)benzamide	Investigative	44417834	C29H36N2O3	460.6	CC1(CC(CC(N1CC2=CC3=CC=CC=C3C=C2)(C)C)NC(=O)C4=CC(=CC(=C4)OC)OC)C	Ki ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BF2CR7	(1R,5S,6r)-N-(3,4-Difluorobenzyl)-3-(naphthalen-2-ylmethyl)-3-azabicyclo[3.1.0]hexane-6-carboxamide	Investigative	44417840	C24H22F2N2O	392.4	C1[C@@H]2[C@@H](C2C(=O)NCC3=CC(=C(C=C3)F)F)CN1CC4=CC5=CC=CC=C5C=C4	Ki ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BG02FN	2-(4-Benzyloxy-benzylamino)-N-[3-(2-pyrrolidin-1-yl-ethyl)-3H-benzoimidazol-5-yl]-acetamide	Investigative	11259560	C28H30N4O2	454.6	C1CCN(C1)CCN2C=NC3=C2C=C(C=C3)NC(=O)CC4=CC=C(C=C4)OCC5=CC=CC=C5	IC50 = 161000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BI92ZF	N-[4-[2-(Dimethylamino)ethylcarbamoyl]phenyl]-4-phenylbenzamide	Investigative	10385550	C24H25N3O2	387.5	CN(C)CCNC(=O)C1=CC=C(C=C1)NC(=O)C2=CC=C(C=C2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BIP0Q9	3,5-Dimethoxy-N-(1-(3-phenylpropyl)piperidin-4-yl)benzamide	Investigative	44417882	C23H30N2O3	382.5	COC1=CC(=CC(=C1)C(=O)NC2CCN(CC2)CCCC3=CC=CC=C3)OC	Ki ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BJS91Z	4-(4-(3-Bromophenylamino)phthalazin-1-yl)benzamide	Investigative	44402861	C21H15BrN4O	419.3	C1=CC=C2C(=C1)C(=NN=C2NC3=CC(=CC=C3)Br)C4=CC=C(C=C4)C(=O)N	Ki ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BO7EX5	(S)-1-(6-((1H-Imidazol-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4-(4-fluorophenethyl)piperazin-2-one	Investigative	44417893	C26H29FN4O	432.5	C1CC2=C(C[C@H]1N3CCN(CC3=O)CCC4=CC=C(C=C4)F)C=CC(=C2)CN5C=CN=C5	Ki = 52000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BP0R9W	3,5-Dimethoxy-N-(3-(naphthalen-2-ylmethylamino)propyl)benzamide	Investigative	44417851	C23H26N2O3	378.5	COC1=CC(=CC(=C1)C(=O)NCCCNCC2=CC3=CC=CC=C3C=C2)OC	Ki ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BQV50E	N-[2-(Diethylamino)ethyl]-2-methoxy-4-[methyl-[methyl-(4-phenoxyphenyl)carbamoyl]amino]benzamide	Investigative	44394978	C29H36N4O4	504.6	CCN(CC)CCNC(=O)C1=C(C=C(C=C1)N(C)C(=O)N(C)C2=CC=C(C=C2)OC3=CC=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BU46YA	(S)-4-(4-Fluorophenethyl)-1-(6-((2,2,2-trifluoroethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one	Investigative	44417918	C25H29F4N3O	463.5	C1CC2=C(C[C@H]1N3CCN(CC3=O)CCC4=CC=C(C=C4)F)C=CC(=C2)CNCC(F)(F)F	Ki = 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BV5G9O	5-Chloro-N-(2-diethylamino-ethyl)-2-methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-benzamide	Investigative	44394977	C27H31ClN4O4	511	CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)NC(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BYCR64	1-[(2S)-6-[(1,1-Dioxo-1,4-thiazinan-4-yl)methyl]-1,2,3,4-tetrahydronaphthalen-2-yl]-4-[2-(4-fluorophenyl)ethyl]piperazin-2-one	Investigative	44417908	C27H34FN3O3S	499.6	C1CC2=C(C[C@H]1N3CCN(CC3=O)CCC4=CC=C(C=C4)F)C=CC(=C2)CN5CCS(=O)(=O)CC5	Ki = 94000 nM	Poor binder
T09572	Melanin-concentrating hormone receptor 1	BZYJ51	1-((S)-6-(((2R,6S)-2,6-Dimethylpiperidin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4-(4-fluorophenethyl)piperazin-2-one	Investigative	44417920	C30H40FN3O	477.7	C[C@@H]1CCC[C@@H](N1CC2=CC3=C(C[C@H](CC3)N4CCN(CC4=O)CCC5=CC=C(C=C5)F)C=C2)C	Ki = 62000 nM	Poor binder