TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T10877 Cyclic ADP-ribose hydrolase 1 D0U3EP Resveratrol Phase 3 445154 C14H12O3 228.24 C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O IC50 ~ 100000 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 D0E3LP SEN-196 Phase 2 5113032 C13H13ClN2O 248.71 C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N IC50 ~ 100000 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 B4WY9T 2-Methyl-furan-3-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide Investigative 136124133 C13H12N2O4 260.24 CC1=C(C=CO1)C(=O)N/N=C\\C2=CC(=C(C=C2)O)O IC50 = 109000 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 B67LDC N'-(2-Hydroxybenzoyl)-2-methylfuran-3-carbohydrazide Investigative 24285123 C13H12N2O4 260.24 CC1=C(C=CO1)C(=O)NNC(=O)C2=CC=CC=C2O IC50 = 120000 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 B90BWX Epicatechin Investigative 1203 C15H14O6 290.27 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O IC50 ~ 100000 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 B96BLI N'-[(1Z)-(4-Hydroxy-3-methoxyphenyl)methylene]-2-methyl-3-furohydrazide Investigative 135949782 C14H14N2O4 274.27 CC1=C(C=CO1)C(=O)N/N=C\\C2=CC(=C(C=C2)O)OC IC50 = 103000 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 B9L1KI 2-Chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide Investigative 3612016 C14H15ClN2O 262.73 C1CCC2=C(C(C1)C(=O)N)NC3=C2C=C(C=C3)Cl IC50 ~ 100000 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 BPEM34 Fisetinidin Investigative 12309895 C15H11O5+ 271.24 C1=CC(=CC2=[O+]C(=C(C=C21)O)C3=CC(=C(C=C3)O)O)O IC50 = 70300 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 BRG48W 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Investigative 661302 C14H16N2O 228.29 CC1=CC2=C(C=C1)NC3=C2CCCC3C(=O)N IC50 ~ 100000 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 BWQX15 (2R,3R,4S,5R,13R,14S,15R,16R)-18-Bromo-3,4,8,10,14,15-hexahydroxy-8,10-dioxo-7,9,11,25,26-pentaoxa-1,17,19,22-tetraza-8lambda5,10lambda5-diphosphapentacyclo[18.3.1.12,5.113,16.017,21]hexacosa-18,20,22-trien-24-one Investigative 11170346 C15H19BrN4O14P2 621.18 C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(C3=O)N=C(N4[C@H]5[C@@H]([C@@H]([C@H](O5)COP(=O)(OP(=O)(O1)O)O)O)O)Br)O)O IC50 = 158000 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 D0E1QP 2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Investigative 4262314 C13H14N2O 214.26 C1CC(C2=C(C1)C3=CC=CC=C3N2)C(=O)N IC50 ~ 100000 nM Poor binder T10877 Cyclic ADP-ribose hydrolase 1 D0O0VZ Piceatannol Investigative 667639 C14H12O4 244.24 C1=CC(=C(C=C1/C=C/C2=CC(=CC(=C2)O)O)O)O IC50 ~ 100000 nM Poor binder