TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T11241	Sphingosine-1-phosphate receptor 3	B1UHN2	3-[3,5-Bis(trifluoromethyl)phenyl]-5-[2-(1-phenylcyclohexyl)ethyl]-1,2,4-oxadiazole	Investigative	56948656	C24H22F6N2O	468.4	C1CCC(CC1)(CCC2=NC(=NO2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C4=CC=CC=C4	EC50 ~ 62000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	B25YGV	5-[3-[7-(1,3-Dihydroxypropan-2-yl)-4-methyl-6,8-dihydro-5H-1,7-naphthyridin-3-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile	Investigative	54756907	C24H27N5O4	449.5	CC1=C2CCN(CC2=NC=C1C3=NOC(=N3)C4=CC(=C(C=C4)OC(C)C)C#N)C(CO)CO	EC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	B27HCT	N-Cyclohexyl-5-cyclopropylisoxazole-3-carboxamide	Investigative	16188020	C13H18N2O2	234.29	C1CCC(CC1)NC(=O)C2=NOC(=C2)C3CC3	EC50 ~ 50000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	B3D7XF	2-(7-(5-(3-Cyano-5-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-3-yl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic Acid	Investigative	42630194	C23H15F3N4O4	468.4	C1CC2=C(C1CC(=O)O)NC3=C2C=C(C=C3)C4=NOC(=N4)C5=CC(=CC(=C5)C#N)OC(F)(F)F	EC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	B43SDT	2-Amino-2-methyl-4-(3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydronaphtho[1,2-c]isoxazol-7-yl)butan-1-ol	Investigative	67171863	C26H24F3N3O3	483.5	CC(CCC1=CC2=C(C=C1)C3=NOC(=C3CC2)C4=NOC(=C4C(F)(F)F)C5=CC=CC=C5)(CO)N	EC50 ~ 63000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	B53RMO	C1=CC(CC(C)C)=CC=C1C1=C(Ccc=2C3=CC=C(O)C=2)C3=NO1	Investigative	136374642	C21H21NO2	319.4	CC(C)CC1=CC=C(C=C1)C2=C3CCC4=C(C3=NO2)C=CC(=C4)O	EC50 ~ 63000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	B5HMI7	5-[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]pentanoic acid	Investigative	134130884	C24H23NO2S	389.5	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCCCCC(=O)O	EC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	B62BZO	6-(Cyclohexyl(cyclopropylmethyl)amino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide	Investigative	25182769	C22H28N4O2	380.5	CC1=C(C=CC(=C1)O)NC(=O)C2=CC(=NC=N2)N(CC3CC3)C4CCCCC4	EC50 = 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	B8C2JN	1-[(5-Naphthalen-2-yl-1-benzothiophen-2-yl)methyl]azetidine-3-carboxylic acid	Investigative	134130169	C23H19NO2S	373.5	C1C(CN1CC2=CC3=C(S2)C=CC(=C3)C4=CC5=CC=CC=C5C=C4)C(=O)O	EC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	B95UVZ	[4-[[3-[5-Phenyl-4-(trifluoromethyl)-1,2-oxazol-3-yl]-4,5-dihydrobenzo[g][2,1]benzoxazol-7-yl]methyl]morpholin-3-yl]methanol	Investigative	68192027	C27H24F3N3O4	511.5	C1CC2=C(ON=C2C3=C1C=C(C=C3)CN4CCOCC4CO)C5=NOC(=C5C(F)(F)F)C6=CC=CC=C6	EC50 ~ 63000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	B9P8DB	2-[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]acetic acid	Investigative	134130695	C21H17NO2S	347.4	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCC(=O)O	EC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BBL4N5	C=12Ccc3=CC(O)=CC=C3C2=noc=1C(=NO1)C=C1C1=CC=CC=C1	Investigative	136374592	C20H14N2O3	330.3	C1CC2=C(ON=C2C3=C1C=C(C=C3)O)C4=NOC(=C4)C5=CC=CC=C5	EC50 ~ 63000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BE8PY2	4-[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]butanoic acid	Investigative	134131381	C23H21NO2S	375.5	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCCCC(=O)O	EC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BEHF32	5-[2-(1-Phenylcyclohexyl)ethyl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole	Investigative	56948896	C23H23F3N2O2	416.4	C1CCC(CC1)(CCC2=NC(=NO2)C3=CC=C(C=C3)OC(F)(F)F)C4=CC=CC=C4	EC50 ~ 62000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BK3M6F	1-((3-(3-Phenyl-4-(trifluoromethyl)isoxazol-5-yl)-4,5-dihydro-2H-benzo[g]indazol-7-yl)methyl)azetidine-3-carboxylic acid	Investigative	67169024	C26H21F3N4O3	494.5	C1CC2=C(NN=C2C3=C1C=C(C=C3)CN4CC(C4)C(=O)O)C5=C(C(=NO5)C6=CC=CC=C6)C(F)(F)F	EC50 ~ 63000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BKY20I	1-({4-[5-(4-Propylphenyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)azetidine-3-carboxylic acid	Investigative	10317453	C22H23N3O3	377.4	CCCC1=CC=C(C=C1)C2=NC(=NO2)C3=CC=C(C=C3)CN4CC(C4)C(=O)O	IC50 = 58000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BL08QC	N,N-Dicyclohexyl-1,2-benzoxazole-3-carboxamide	Investigative	25110524	C20H26N2O2	326.4	C1CCC(CC1)N(C2CCCCC2)C(=O)C3=NOC4=CC=CC=C43	EC50 ~ 50000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BN0T6U	CID 44517795	Investigative	44517795	C22H15F3N4O5	472.4	C1CN(C2=C1C=C(C=C2)C3=NOC(=N3)C4=CC(=CC(=C4)C#N)OC(F)(F)F)C(=O)CCC(=O)O	EC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BP6I0S	N,N-Dicyclohexyl-5-cyclopropylfuran-2-carboxamide	Investigative	25110522	C20H29NO2	315.4	C1CCC(CC1)N(C2CCCCC2)C(=O)C3=CC=C(O3)C4CC4	EC50 ~ 50000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BPH2S4	2-(7-(5-(3-Cyano-5-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acid	Investigative	44138103	C23H15F3N4O4	468.4	C1CN2C3=C(C=C(C=C3)C4=NOC(=N4)C5=CC(=CC(=C5)C#N)OC(F)(F)F)C=C2C1CC(=O)O	EC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BQ3H5B	N,N-Dicyclohexyl-2-cyclopropyl-1,3-oxazole-4-carboxamide	Investigative	25110521	C19H28N2O2	316.4	C1CCC(CC1)N(C2CCCCC2)C(=O)C3=COC(=N3)C4CC4	EC50 ~ 50000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BQ43ZB	3-[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]propanoic acid	Investigative	134130546	C22H19NO2S	361.5	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCCC(=O)O	EC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BRE9B3	(R)-2-Amino-2-(4-(4-(2-(biphenyl-4-yl)ethoxy)-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)propyl dihydrogen phosphate	Investigative	46885798	C27H27F3N3O5P	561.5	C[C@](COP(=O)(O)O)(C1=NC=C(N1)C2=CC(=C(C=C2)OCCC3=CC=C(C=C3)C4=CC=CC=C4)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BTP8G2	4-[[(4-Naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]methyl]benzoic acid	Investigative	134130548	C27H21NO2S	423.5	C1=CC=C2C=C(C=CC2=C1)C3=C4C=C(SC4=CC=C3)CNCC5=CC=C(C=C5)C(=O)O	EC50 ~ 100000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BVWK65	N-Cyclohexyl-5-propyl-3-isoxazolecarboxamide	Investigative	5307570	C13H20N2O2	236.31	CCCC1=CC(=NO1)C(=O)NC2CCCCC2	EC50 ~ 50000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BWHI48	N-Cyclohexyl-N-phenyl-5-propyl-1,2-oxazole-3-carboxamide	Investigative	25110105	C19H24N2O2	312.4	CCCC1=CC(=NO1)C(=O)N(C2CCCCC2)C3=CC=CC=C3	EC50 ~ 50000 nM	Poor binder
T11241	Sphingosine-1-phosphate receptor 3	BZ6EI1	4-({[7-(Naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	Investigative	124221654	C23H21NO2S	375.5	C1=CC=C2C=C(C=CC2=C1)C3=CC=CC4=C3SC(=C4)CNCCCC(=O)O	EC50 ~ 100000 nM	Poor binder