TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T11448	Adrenergic receptor alpha-2A	B0JVO6	1-Benzyl-4-(pentylamino)-6-methylpyridine-2(1H)-one	Investigative	127052992	C18H24N2O	284.4	CCCCCNC1=CC(=O)N(C(=C1)C)CC2=CC=CC=C2	Ki = 110000 nM	Poor binder
T11448	Adrenergic receptor alpha-2A	B6FR9Z	1-Benzyl-4-(isopentylamino)-6-methylpyridine-2(1H)-one	Investigative	127050218	C18H24N2O	284.4	CC1=CC(=CC(=O)N1CC2=CC=CC=C2)NCCC(C)C	Ki = 110000 nM	Poor binder
T11448	Adrenergic receptor alpha-2A	B7KW2M	1-Pentyl-4-[(4-chlorobenzyl)amino]-6-methylpyridine-2(1H)-one	Investigative	127048644	C18H23ClN2O	318.8	CCCCCN1C(=CC(=CC1=O)NCC2=CC=C(C=C2)Cl)C	Ki = 80000 nM	Poor binder
T11448	Adrenergic receptor alpha-2A	BCEZ28	1-Isopentyl-4-(4-chlorobenzylamino)-6-methylpyridine-2(1H)-one	Investigative	127051133	C18H23ClN2O	318.8	CC1=CC(=CC(=O)N1CCC(C)C)NCC2=CC=C(C=C2)Cl	Ki = 99000 nM	Poor binder
T11448	Adrenergic receptor alpha-2A	BFJ08I	1H-Imidazol-5-yl(naphthalen-1-yl)methanol;hydrochloride	Investigative	45260744	C14H13ClN2O	260.72	C1=CC=C2C(=C1)C=CC=C2C(C3=CN=CN3)O.Cl	IC50 = 61900 nM	Poor binder
T11448	Adrenergic receptor alpha-2A	BFQ59E	1-Pentyl-4-(pentylamino)-6-methylpyridine-2(1H)-one	Investigative	127048643	C16H28N2O	264.41	CCCCCNC1=CC(=O)N(C(=C1)C)CCCCC	Ki = 62000 nM	Poor binder
T11448	Adrenergic receptor alpha-2A	BTN06M	1-Isopentyl-4-(isopentylamino)-6-methylpyridine-2(1H)-one	Investigative	127048645	C16H28N2O	264.41	CC1=CC(=CC(=O)N1CCC(C)C)NCCC(C)C	Ki = 52000 nM	Poor binder
T11448	Adrenergic receptor alpha-2A	BXYW90	1-Isobutyl-4-[[4-(trifluoromethyl)benzyl]amino]-6-methylpyridine-2(1H)-one	Investigative	127048642	C18H21F3N2O	338.4	CC1=CC(=CC(=O)N1CC(C)C)NCC2=CC=C(C=C2)C(F)(F)F	Ki = 58000 nM	Poor binder