TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T12059	Lysosomal alpha-mannosidase	B07VDO	(3S,5R)-1-Decyl-4-(2-hydroxyethyl)piperidine-3,4,5-triol	Investigative	118717612	C17H35NO4	317.5	CCCCCCCCCCN1C[C@H](C([C@H](C1)O)(CCO)O)O	IC50 = 112000 nM	Poor binder
T12059	Lysosomal alpha-mannosidase	B16POU	(R)-2-(((2R,3R,4S)-3,4-Dihydroxypyrrolidin-2-yl)methylamino)-2-phenylethyl 4-bromobenzoate	Investigative	11441920	C20H23BrN2O4	435.3	C1[C@@H]([C@@H]([C@H](N1)CN[C@@H](COC(=O)C2=CC=C(C=C2)Br)C3=CC=CC=C3)O)O	IC50 = 75000 nM	Poor binder
T12059	Lysosomal alpha-mannosidase	B1BED6	(3r,4r,5r)-3,4-Dihydroxy-5-({[(1r)-2-Hydroxy-1-Phenylethyl]amino}methyl)pyrrolidin-2-One	Investigative	24832045	C13H18N2O4	266.29	C1=CC=C(C=C1)[C@H](CO)NC[C@@H]2[C@H]([C@H](C(=O)N2)O)O	IC50 = 50000 nM	Poor binder
T12059	Lysosomal alpha-mannosidase	B3J8AY	(R)-2-(((2R,3R,4R)-3,4-Dihydroxy-1-methyl-5-oxopyrrolidin-2-yl)methylamino)-2-phenylethyl 4-bromobenzoate	Investigative	25147648	C21H23BrN2O5	463.3	CN1[C@@H]([C@H]([C@H](C1=O)O)O)CN[C@@H](COC(=O)C2=CC=C(C=C2)Br)C3=CC=CC=C3	IC50 = 75000 nM	Poor binder
T12059	Lysosomal alpha-mannosidase	B5GOT0	(3R,5S)-4-(2-Hydroxyethyl)-1-octylpiperidine-3,4,5-triol	Investigative	118717611	C15H31NO4	289.41	CCCCCCCCN1C[C@H](C([C@H](C1)O)(CCO)O)O	IC50 = 143000 nM	Poor binder
T12059	Lysosomal alpha-mannosidase	BH81KU	(3R,5S)-1-Hexyl-4-(2-hydroxyethyl)piperidine-3,4,5-triol	Investigative	118717610	C13H27NO4	261.36	CCCCCCN1C[C@H](C([C@H](C1)O)(CCO)O)O	IC50 = 183000 nM	Poor binder
T12059	Epididymis-specific alpha-mannosidase	BICY89	3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3S,4R,5R)-	Investigative	6603829	C6H13NO4	163.17	C1[C@H]([C@H]([C@H]([C@@H](N1)CO)O)O)O	IC50 = 59000 nM	Poor binder
T12059	Lysosomal alpha-mannosidase	BICY89	3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3S,4R,5R)-	Investigative	6603829	C6H13NO4	163.17	C1[C@H]([C@H]([C@H]([C@@H](N1)CO)O)O)O	IC50 = 64000 nM	Poor binder
T12059	Lysosomal alpha-mannosidase	BJ5TF2	(R)-2-(((2R,3R,4R)-3,4-Dihydroxy-5-oxopyrrolidin-2-yl)methylamino)-2-phenylethyl 4-bromobenzoate	Investigative	44578591	C20H21BrN2O5	449.3	C1=CC=C(C=C1)[C@H](COC(=O)C2=CC=C(C=C2)Br)NC[C@@H]3[C@H]([C@H](C(=O)N3)O)O	IC50 = 75000 nM	Poor binder
T12059	Lysosomal alpha-mannosidase	BSH9E4	(2R,3R,4S)-2-({[(1R)-2-Hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diol	Investigative	11425273	C13H20N2O3	252.31	C1[C@@H]([C@@H]([C@H](N1)CN[C@@H](CO)C2=CC=CC=C2)O)O	IC50 = 50000 nM	Poor binder