TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T13127	Farnesyl protein transferase	D01GBY	Desloratadine	Approved	124087	C19H19ClN2	310.8	C1CC2=C(C=CC(=C2)Cl)C(=C3CCNCC3)C4=C1C=CC=N4	IC50 ~ 65000 nM	Poor binder
T13127	Farnesyl protein transferase	D03GQH	B-581	Terminated	132887	C22H38N4O3S2	470.7	CC(C)[C@@H](CN[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCSC)C(=O)O)NC[C@H](CS)N	IC50 = 50000 nM	Poor binder
T13127	Farnesyl protein transferase	D0N1XD	Gliotoxin	Terminated	6223	C13H14N2O4S2	326.4	CN1C(=O)[C@]23CC4=CC=C[C@@H]([C@H]4N2C(=O)[C@]1(SS3)CO)O	IC50 = 80000 nM	Poor binder
T13127	Farnesyl protein transferase	B0I6QB	2-Methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dione	Investigative	300707	C12H10N2O2	214.22	CN1CC(=O)N2C3=CC=CC=C3C=C2C1=O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B0ZH8A	3-Benzoyl-7-methylindolizine-1-carboxylic acid	Investigative	118724660	C17H13NO3	279.29	CC1=CC2=C(C=C(N2C=C1)C(=O)C3=CC=CC=C3)C(=O)O	IC50 = 72300 nM	Poor binder
T13127	Farnesyl protein transferase	B14BAN	6-Hydroxy-8-methyl-3-[2-[(1S,6S)-2,2,6-trimethylcyclohexyl]ethyl]-2,5-dihydro-1-benzoxepine-9-carbaldehyde	Investigative	53321567	C23H32O3	356.5	C[C@H]1CCCC([C@H]1CCC2=CCC3=C(C=C(C(=C3OC2)C=O)C)O)(C)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B1LQ2K	2-Ethyl-butyric acid 2-((10R,11S,13S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester	Investigative	44359694	C27H40O6	460.6	CCC(CC)C(=O)OCC(=O)[C@]1(CCC2[C@@]1(C[C@@H](C3C2CCC4=CC(=O)CC[C@]34C)O)C)O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B1MV0A	(S)-2-[((S)-2-{2-[Tert-Butoxycarbonyl-(2-mercapto-ethyl)-amino]-acetyl}-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl)-amino]-4-methylsulfanyl-butyric acid methyl ester	Investigative	44323761	C25H37N3O6S2	539.7	CC(C)(C)OC(=O)N(CCS)CC(=O)N1CC2=CC=CC=C2C[C@H]1C(=O)N[C@@H](CCSC)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B1REK7	[(3Z)-4-[4-(Dimethylamino)pyridin-1-ium-1-yl]-2-ethoxycarbonyl-5-(4-fluorophenyl)-5-oxopenta-1,3-dienylidene]azanide	Investigative	136244597	C21H20FN3O3	381.4	CCOC(=O)C(=C=[N-])/C=C(/C(=O)C1=CC=C(C=C1)F)\\[N+]2=CC=C(C=C2)N(C)C	IC50 = 62300 nM	Poor binder
T13127	Farnesyl protein transferase	B24UTY	(S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-2-ylmethyl)-amino]-benzoylamino}-pentanoic acid	Investigative	10552209	C29H29N3O3	467.6	CC(C)C[C@@H](C(=O)O)NC(=O)C1=C(C=C(C=C1)NCC2=CC=CC=N2)C3=CC=CC4=CC=CC=C43	IC50 = 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B29CKW	2-[3-[5-[[[(2S)-1-[[(2S)-1-[[(1S)-1-Carboxy-3-methylsulfanylpropyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]methyl]-1-methylimidazol-2-yl]propyl]butanedioic acid	Investigative	23643650	C31H45N5O8S	647.8	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCSC)C(=O)O)NCC2=CN=C(N2C)CCCC(CC(=O)O)C(=O)O	IC50 = 60000 nM	Poor binder
T13127	Farnesyl protein transferase	B2AU7C	4-Oxo-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoxy]butanoic acid	Investigative	10403878	C19H30O4	322.4	CC(=CCC/C(=C/CC/C(=C/COC(=O)CCC(=O)O)/C)/C)C	IC50 = 130000 nM	Poor binder
T13127	Farnesyl protein transferase	B2CR6A	1-[1-(4-Cyanobenzyl)-1H-imidazole-5-ylmethyl]-4-(3-chlorophenyl)piperazine-2-one	Investigative	9866014	C22H20ClN5O	405.9	C1CN(C(=O)CN1C2=CC(=CC=C2)Cl)CC3=CN=CN3CC4=CC=C(C=C4)C#N	IC50 = 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B2I3CB	[(2S,10R,13R)-17-(1,5-Dimethyl-hexyl)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-2-yl]-acetic acid ethyl ester	Investigative	44359440	C31H50O3	470.7	CCOC(=O)C[C@@H]1C[C@@]2(C3CC[C@]4(C(C3CCC2=CC1=O)CCC4C(C)CCCC(C)C)C)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B2YMP7	(2S)-2-[3-(Dibenzofuran-4-yl)-4-cyano-5-(isopropylthio)thiophene-2-ylcarbonylamino]-4-(methylthio)butanoic acid methyl ester	Investigative	76336564	C27H26N2O4S3	538.7	CC(C)SC1=C(C(=C(S1)C(=O)N[C@@H](CCSC)C(=O)OC)C2=CC=CC3=C2OC4=CC=CC=C34)C#N	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B30HIE	(2S,3S)-2-Imidazol-1-ylmethyl-2,3,5,6,7,8-hexahydro-naphtho[2,3-b]thiophen-3-ol	Investigative	10803148	C16H18N2OS	286.4	C1CCC2=CC3=C(C=C2C1)[C@@H]([C@@H](S3)CN4C=CN=C4)O	IC50 ~ 70000 nM	Poor binder
T13127	Farnesyl protein transferase	B31HEX	1-[1-(3H-Imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-2-(4-methoxy-phenyl)-ethane-1,2-dione	Investigative	10837934	C28H26N4O3	466.5	COC1=CC=C(C=C1)C(=O)C(=O)N2CCN(C3=C(C2)C=C(C=C3)C4=CC=CC=C4)CC5=CN=CN5	IC50 = 91000 nM	Poor binder
T13127	Farnesyl protein transferase	B32ZPA	N'-[2-(Methylthio)ethyl]-N'-(ethoxycarbonylmethyl)-3-(4-chlorophenyl)-4-cyano-5-(isopropylthio)-2-thiophenecarbohydrazide	Investigative	76311227	C22H26ClN3O3S3	512.1	CCOC(=O)CN(CCSC)NC(=O)C1=C(C(=C(S1)SC(C)C)C#N)C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B36YLM	1-(1H-Imidazole-5-ylmethyl)-4-(1-naphthylcarbonyl)-7-phenyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine	Investigative	10253637	C30H26N4O	458.6	C1CN(C2=C(CN1C(=O)C3=CC=CC4=CC=CC=C43)C=C(C=C2)C5=CC=CC=C5)CC6=CN=CN6	IC50 = 95000 nM	Poor binder
T13127	Farnesyl protein transferase	B39VXO	4-Cyano-3-(2,4-dimethoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylic acid	Investigative	90667636	C17H17NO4S2	363.5	CC(C)SC1=C(C(=C(S1)C(=O)O)C2=C(C=C(C=C2)OC)OC)C#N	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B3G1TI	Methyl (2R)-2-[[3-(4-chlorophenyl)-4-cyano-5-propan-2-ylsulfanylthiophene-2-carbonyl]amino]-4-methylsulfanylbutanoate	Investigative	45484000	C21H23ClN2O3S3	483.1	CC(C)SC1=C(C(=C(S1)C(=O)N[C@H](CCSC)C(=O)OC)C2=CC=C(C=C2)Cl)C#N	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B3NZ8C	3'-[[[(R)-2-Amino-3-mercaptopropionyl]amino]methyl]-1,1'-biphenyl-3-carboxylic acid	Investigative	10496660	C17H18N2O3S	330.4	C1=CC(=CC(=C1)C2=CC(=CC=C2)C(=O)O)CNC(=O)[C@H](CS)N	IC50 = 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B3V9GD	3-Benzoyl-5-methyl-N-prop-2-ynylindolizine-1-carboxamide	Investigative	118724666	C20H16N2O2	316.4	CC1=CC=CC2=C(C=C(N12)C(=O)C3=CC=CC=C3)C(=O)NCC#C	IC50 = 57800 nM	Poor binder
T13127	Farnesyl protein transferase	B4FO3Q	Ethyl 4-cyano-3-(2,4-dimethoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylate	Investigative	90667635	C19H21NO4S2	391.5	CCOC(=O)C1=C(C(=C(S1)SC(C)C)C#N)C2=C(C=C(C=C2)OC)OC	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B4MNJ8	Kurasoin A	Investigative	4476323	C16H14O3	254.28	C1=CC=C(C=C1)CC(=O)C(=O)CC2=CC=C(C=C2)O	IC50 = 59000 nM	Poor binder
T13127	Farnesyl protein transferase	B4TJ7V	Methyl (2S)-2-[[(2S,3S)-2-[(4-cyano-3-phenyl-5-propan-2-ylsulfanylthiophene-2-carbonyl)amino]-3-methylpentanoyl]amino]-4-methylsulfanylbutanoate	Investigative	76318444	C27H35N3O4S3	561.8	CC[C@H](C)[C@@H](C(=O)N[C@@H](CCSC)C(=O)OC)NC(=O)C1=C(C(=C(S1)SC(C)C)C#N)C2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B5EYQ3	5-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3a,4,7,7a-tetrahydro-isobenzofuran-1,3-dione	Investigative	13137195	C19H26O3	302.4	CC(=CCC/C(=C/CCC1=CCC2C(C1)C(=O)OC2=O)/C)C	IC50 = 190000 nM	Poor binder
T13127	Farnesyl protein transferase	B5IC2S	2-[(2-Methoxyphenyl)acetyl]-4alpha,9alpha-ethano-5-hydroxy-9-phenyl-2,3,4,9-tetrahydro-1H-benzo[f]isoindole-3abeta(9abetaH)-carboxylic acid	Investigative	44296782	C30H29NO5	483.6	COC1=CC=CC=C1CC(=O)N2C[C@H]3[C@]4(CC[C@@H]([C@]3(C2)C(=O)O)C5=C4C=CC=C5O)C6=CC=CC=C6	Ki = 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B5Q0WM	CID 44359605	Investigative	44359605	C20H26O8	394.4	C[C@]12CC(=O)C3C(C1CC[C@]24C5(COCO5)OCO4)CCC(=O)[C@]3(C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B5QNY2	[1-(3H-Imidazol-4-ylmethyl)-7-pyridin-2-yl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone	Investigative	10647606	C29H25N5O	459.5	C1CN(C2=C(CN1C(=O)C3=CC=CC4=CC=CC=C43)C=C(C=C2)C5=CC=CC=N5)CC6=CN=CN6	IC50 = 177000 nM	Poor binder
T13127	Farnesyl protein transferase	B64BTI	(2S)-4-Methyl-2-[[2-naphthalen-1-yl-4-(pyridin-4-ylmethylamino)benzoyl]amino]pentanoic Acid	Investigative	10600336	C29H29N3O3	467.6	CC(C)C[C@@H](C(=O)O)NC(=O)C1=C(C=C(C=C1)NCC2=CC=NC=C2)C3=CC=CC4=CC=CC=C43	IC50 = 58000 nM	Poor binder
T13127	Farnesyl protein transferase	B6EWJ9	4-Cyano-5-propan-2-ylsulfanyl-3-(3,4,5-trimethoxyphenyl)thiophene-2-carboxylic acid	Investigative	90667624	C18H19NO5S2	393.5	CC(C)SC1=C(C(=C(S1)C(=O)O)C2=CC(=C(C(=C2)OC)OC)OC)C#N	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B6GD1L	3-[(3Ar,6R,9S)-3-(1,5-Dimethyl-hexyl)-3a,6,9-trimethyl-7-oxo-dodecahydro-cyclopenta[a]naphthalen-6-yl]-propionic acid methyl ester	Investigative	44359483	C28H48O3	432.7	C[C@H]1CC(=O)[C@](C2C1C3CCC([C@]3(CC2)C)C(C)CCCC(C)C)(C)CCC(=O)OC	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B6PI3A	2-(Benzoyl-piperidin-4-yl-amino)-4-methylsulfanyl-butyric acid methyl ester	Investigative	11121668	C18H26N2O3S	350.5	COC(=O)[C@H](CCSC)N(C1CCNCC1)C(=O)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B6XB1U	2,4-Dihydroxy-3-[2-hydroxy-3-methyl-5-[(1S,6S)-2,2,6-trimethylcyclohexyl]pentyl]-6-methylbenzaldehyde	Investigative	53320241	C23H36O4	376.5	C[C@H]1CCCC([C@H]1CCC(C)C(CC2=C(C=C(C(=C2O)C=O)C)O)O)(C)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B75CLN	(5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trienoic acid	Investigative	11076782	C18H30O2	278.4	CC(=CCC/C(=C/CC/C(=C/CCCC(=O)O)/C)/C)C	IC50 = 170000 nM	Poor binder
T13127	Farnesyl protein transferase	B7KX4E	3-[(3Ar,6R,9S)-3-(1,5-Dimethyl-hexyl)-9-ethyl-3a,6-dimethyl-7-oxo-dodecahydro-cyclopenta[a]naphthalen-6-yl]-propionic acid	Investigative	44359434	C28H48O3	432.7	CC[C@H]1CC(=O)[C@](C2C1C3CCC([C@]3(CC2)C)C(C)CCCC(C)C)(C)CCC(=O)O	IC50 = 60000 nM	Poor binder
T13127	Farnesyl protein transferase	B7L6UQ	(2R)-2-(3-Carbazol-9-ylpropanoylamino)-3-sulfanylpropanoic acid	Investigative	122192720	C18H18N2O3S	342.4	C1=CC=C2C(=C1)C3=CC=CC=C3N2CCC(=O)N[C@@H](CS)C(=O)O	IC50 = 65400 nM	Poor binder
T13127	Farnesyl protein transferase	B84EZS	(10R,13S)-17-(2-Hydroxy-acetyl)-10,13-dimethyl-1,6,7,8,9,10,12,13,14,15,16,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,11-dione	Investigative	44359721	C21H28O4	344.4	C[C@]12CCC(=O)C=C1CCC3C2C(=O)C[C@]4(C3CCC4C(=O)CO)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B85LUM	(S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}-benzoylamino)-4-methylsulfanyl-butyric acid	Investigative	15834370	C17H22N4O3S	362.4	CSCC[C@@H](C(=O)O)NC(=O)C1=CC=CC(=C1)CNCC2=CN=CN2	IC50 = 57600 nM	Poor binder
T13127	Farnesyl protein transferase	B85XCQ	4-Cyano-3-(3,5-dimethoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylic acid	Investigative	90667632	C17H17NO4S2	363.5	CC(C)SC1=C(C(=C(S1)C(=O)O)C2=CC(=CC(=C2)OC)OC)C#N	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B8B7AQ	2,4-Dihydroxy-6-methyl-3-[3-methylidene-2-oxo-5-[(1S,6S)-2,2,6-trimethylcyclohexyl]pentyl]benzaldehyde	Investigative	53326789	C23H32O4	372.5	C[C@H]1CCCC([C@H]1CCC(=C)C(=O)CC2=C(C=C(C(=C2O)C=O)C)O)(C)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B8F6QV	Ethyl 4-cyano-3-(3-methoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylate	Investigative	90667615	C18H19NO3S2	361.5	CCOC(=O)C1=C(C(=C(S1)SC(C)C)C#N)C2=CC(=CC=C2)OC	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B8MCV2	Methyl (2S)-2-[(2R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-methylbutanamido]-3-(4-hydroxy-2,3-dimethylphenyl)propanamido]-4-(methylsulfanyl)butanoate	Investigative	23646370	C25H40N4O6S2	556.7	CC1=C(C=CC(=C1C)O)C[C@H](C(=O)N[C@@H](CCSC)C(=O)OC)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CS)N	IC50 = 70500 nM	Poor binder
T13127	Farnesyl protein transferase	B8T0AM	2-[[(4E,8E)-5,9,13-Trimethyltetradeca-4,8,12-trienoyl]amino]propanedioic acid	Investigative	46230681	C20H31NO5	365.5	CC(=CCC/C(=C/CC/C(=C/CCC(=O)NC(C(=O)O)C(=O)O)/C)/C)C	IC50 = 60000 nM	Poor binder
T13127	Farnesyl protein transferase	B91FJU	Methyl (2S)-2-[benzoyl-[1-(1,3-thiazole-4-carbonyl)piperidin-4-yl]amino]-4-methylsulfanylbutanoate;hydrochloride	Investigative	45262448	C22H28ClN3O4S2	498.1	COC(=O)[C@H](CCSC)N(C1CCN(CC1)C(=O)C2=CSC=N2)C(=O)C3=CC=CC=C3.Cl	IC50 = 52500 nM	Poor binder
T13127	Farnesyl protein transferase	B92OAR	3-(2-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiophene-2-carboxylic acid (1l)	Investigative	90667620	C16H15NO3S2	333.4	CC(C)SC1=C(C(=C(S1)C(=O)O)C2=CC=CC=C2OC)C#N	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	B9KJT0	2-Methyl-2,3,10,10a-tetrahydro-pyrazino[1,2-a]indole-1,4-dione	Investigative	300704	C12H12N2O2	216.24	CN1CC(=O)N2C(C1=O)CC3=CC=CC=C32	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B9VSD4	(S)-2-{3-[((R)-2-Acetylamino-3-mercapto-propionylamino)-methyl]-benzoylamino}-4-methylsulfanyl-butyric acid methyl ester	Investigative	44320314	C19H27N3O5S2	441.6	CC(=O)N[C@@H](CS)C(=O)NCC1=CC(=CC=C1)C(=O)N[C@@H](CCSC)C(=O)OC	IC50 = 100000 nM	Poor binder
T13127	Farnesyl protein transferase	B9Y8QL	(2S)-2-[[(3S)-2-[2-[2-[2-[[2-[(3S)-3-[[(1S)-1-Carboxy-3-methylsulfanylpropyl]carbamoyl]-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-[(2-methylpropan-2-yl)oxycarbonyl]amino]ethyldisulfanyl]ethyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]-4-methylsulfanylbutanoic acid	Investigative	44323677	C48H68N6O12S4	1049.4	CC(C)(C)OC(=O)N(CCSSCCN(CC(=O)N1CC2=CC=CC=C2C[C@H]1C(=O)N[C@@H](CCSC)C(=O)O)C(=O)OC(C)(C)C)CC(=O)N3CC4=CC=CC=C4C[C@H]3C(=O)N[C@@H](CCSC)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BADZ70	CID 11603180	Investigative	11603180	C23H32O4	372.5	CC1=CC(=C(C(=C1C=O)O)CC(C(=C)CC/C=C(\\C)/CCC=C(C)C)O)O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BAQ03X	Methyl (2S)-2-[[5-butan-2-ylsulfanyl-3-(4-chlorophenyl)-4-cyanothiophene-2-carbonyl]amino]-4-methylsulfanylbutanoate	Investigative	76329307	C22H25ClN2O3S3	497.1	CCC(C)SC1=C(C(=C(S1)C(=O)N[C@@H](CCSC)C(=O)OC)C2=CC=C(C=C2)Cl)C#N	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BB7IC5	(2E,5E,9E)-6,10,14-Trimethylpentadeca-2,5,9,13-tetraenoic acid	Investigative	46230597	C18H28O2	276.4	CC(=CCC/C(=C/CC/C(=C/C/C=C/C(=O)O)/C)/C)C	IC50 = 130000 nM	Poor binder
T13127	Farnesyl protein transferase	BBG23Y	(7S,10R,13R)-17-(1,5-Dimethyl-hexyl)-7-ethyl-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one	Investigative	44359391	C29H48O	412.7	CC[C@H]1CC2=CC(=O)CC[C@@]2(C3C1C4CCC([C@]4(CC3)C)C(C)CCCC(C)C)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BBKU17	1-(1H-Indol-3-yl)-4-phenylbutane-2,3-dione	Investigative	4476324	C18H15NO2	277.3	C1=CC=C(C=C1)CC(=O)C(=O)CC2=CNC3=CC=CC=C32	IC50 = 59000 nM	Poor binder
T13127	Farnesyl protein transferase	BBLS93	Methyl (2S)-2-[benzoyl-[1-[(4S)-1,3-thiazolidine-4-carbonyl]piperidin-4-yl]amino]-4-methylsulfanylbutanoate;hydrochloride	Investigative	70697542	C22H32ClN3O4S2	502.1	COC(=O)[C@H](CCSC)N(C1CCN(CC1)C(=O)[C@H]2CSCN2)C(=O)C3=CC=CC=C3.Cl	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BBW9G8	Malonic acid 1-(3,7,11-trimethyl-2,6,10-dodecatrienyl) ester	Investigative	46230598	C18H28O4	308.4	CC(=CCC/C(=C/CC/C(=C/COC(=O)CC(=O)O)/C)/C)C	IC50 = 160000 nM	Poor binder
T13127	Farnesyl protein transferase	BC03RW	2-(1H-Indol-3-yl)-N-isopropyl-N-pyridin-4-ylmethyl-acetamide	Investigative	44382032	C19H21N3O	307.4	CC(C)N(CC1=CC=NC=C1)C(=O)CC2=CNC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BCNO97	N-[1-(3H-Imidazol-4-ylmethyl)-4-(naphthalene-1-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-8-yl]-acetamide	Investigative	10789192	C26H25N5O2	439.5	CC(=O)NC1=CC2=C(CN(CCN2CC3=CN=CN3)C(=O)C4=CC=CC5=CC=CC=C54)C=C1	IC50 = 168000 nM	Poor binder
T13127	Farnesyl protein transferase	BD87FW	2,4-Dihydroxy-3-[2-hydroxy-3-methylidene-5-[(1S,6S)-2,2,6-trimethylcyclohexyl]pentyl]-6-methylbenzaldehyde	Investigative	53322894	C23H34O4	374.5	C[C@H]1CCCC([C@H]1CCC(=C)C(CC2=C(C=C(C(=C2O)C=O)C)O)O)(C)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BDPO42	[(3Z)-4-[4-(Dimethylamino)pyridin-1-ium-1-yl]-2-ethoxycarbonyl-5-(4-methoxyphenyl)-5-oxopenta-1,3-dienylidene]azanide	Investigative	136260539	C22H23N3O4	393.4	CCOC(=O)C(=C=[N-])/C=C(/C(=O)C1=CC=C(C=C1)OC)\\[N+]2=CC=C(C=C2)N(C)C	IC50 = 62670 nM	Poor binder
T13127	Farnesyl protein transferase	BDV81Z	(S)-2-[((S)-2-{2-[Tert-Butoxycarbonyl-(2-mercapto-ethyl)-amino]-acetyl}-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl)-amino]-4-methylsulfanyl-butyric acid	Investigative	44323963	C24H35N3O6S2	525.7	CC(C)(C)OC(=O)N(CCS)CC(=O)N1CC2=CC=CC=C2C[C@H]1C(=O)N[C@@H](CCSC)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BE5JL3	(2S)-3-Hydroxy-2-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-[(2-phenylmethoxybenzoyl)amino]butanoyl]amino]pentanoyl]amino]propanoic acid	Investigative	44298944	C28H37N3O7	527.6	CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)C1=CC=CC=C1OCC2=CC=CC=C2	IC50 = 63000 nM	Poor binder
T13127	Farnesyl protein transferase	BE98IG	(2S)-2-[(2R)-3-(4-Hydroxy-2,3-dimethylphenyl)-2-[(2S)-2-[(2R)-2-formamido-3-sulfanylpropanamido]-3-methylbutanamido]propanamido]-4-(methylsulfanyl)butanoic acid	Investigative	11613911	C25H38N4O7S2	570.7	CC1=C(C=CC(=C1C)O)C[C@H](C(=O)N[C@@H](CCSC)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CS)NC=O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BFJ32H	N-(1-Adamantyl)-3-(4-chlorophenyl)-4-cyano-5-(isopropylthio)-2-thiophenecarboxamide	Investigative	76329304	C25H27ClN2OS2	471.1	CC(C)SC1=C(C(=C(S1)C(=O)NC23CC4CC(C2)CC(C4)C3)C5=CC=C(C=C5)Cl)C#N	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BFS1L8	(2S)-3-Hydroxy-2-[[(2S)-2-[[(2S)-2-[(5-hydroxy-2-phenylmethoxybenzoyl)amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]propanoic acid	Investigative	44298991	C28H37N3O8	543.6	CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)C1=C(C=CC(=C1)O)OCC2=CC=CC=C2	IC50 = 137000 nM	Poor binder
T13127	Farnesyl protein transferase	BGO03Z	(E)-4-[4-(Dimethylamino)pyridin-1-ium-1-yl]-5-oxo-5-phenothiazin-10-ylpent-2-enoic acid	Investigative	71718546	C24H22N3O3S+	432.5	CN(C)C1=CC=[N+](C=C1)C(/C=C/C(=O)O)C(=O)N2C3=CC=CC=C3SC4=CC=CC=C42	IC50 = 86490 nM	Poor binder
T13127	Farnesyl protein transferase	BGR78P	CID 11710728	Investigative	11710728	C24H32O4	384.5	CC1=CC(=C(C(=C1C=O)O)CC(C(=C)CCC23CC4CC(C2)CC(C4)C3)O)O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BGWN52	(2S)-2-[[(2S,3S,6S)-6-[[[(2R)-2-Amino-3-(tert-butyldisulfanyl)propanoyl]amino]methyl]-3-phenylmethoxyoxane-2-carbonyl]amino]-4-methylsulfinylbutanoic acid	Investigative	11261954	C26H41N3O7S3	603.8	CC(C)(C)SSC[C@@H](C(=O)NC[C@@H]1CC[C@@H]([C@H](O1)C(=O)N[C@@H](CCS(=O)C)C(=O)O)OCC2=CC=CC=C2)N	IC50 = 91000 nM	Poor binder
T13127	Farnesyl protein transferase	BHEN63	3-Benzyldisulfanyl-2-methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dione	Investigative	44346734	C19H16N2O2S2	368.5	CN1C(C(=O)N2C3=CC=CC=C3C=C2C1=O)SSCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BI9BR4	1-[4-(8-Methoxy-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidin-1-yl]ethanone	Investigative	14885632	C22H24N2O2	348.4	CC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)OC)CC1	IC50 = 56000 nM	Poor binder
T13127	Farnesyl protein transferase	BIF08L	CID 46230685	Investigative	46230685	C17H29NO4S	343.5	CC(=CCC/C(=C/CC/C(=C/CCC(=O)NS(=O)(=O)O)/C)/C)C	IC50 = 85000 nM	Poor binder
T13127	Farnesyl protein transferase	BIWL92	(2S)-3-Hydroxy-2-[[(2S)-2-[[(2S)-2-[(3-hydroxy-2-phenylmethoxybenzoyl)amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]propanoic acid	Investigative	44298963	C28H37N3O8	543.6	CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)C1=C(C(=CC=C1)O)OCC2=CC=CC=C2	IC50 = 157000 nM	Poor binder
T13127	Farnesyl protein transferase	BJ0U8P	3-Oxo-2-(phosphonomethyl)-3-[[(6E)-3,3,7,11-tetramethyldodeca-6,10-dienyl]amino]propanoic acid	Investigative	10387250	C20H36NO6P	417.5	CC(=CCC/C(=C/CCC(C)(C)CCNC(=O)C(CP(=O)(O)O)C(=O)O)/C)C	IC50 = 55000 nM	Poor binder
T13127	Farnesyl protein transferase	BKBG38	3-(5-Cyclohexyl-2-hydroxy-3-methylidenepentyl)-2,4-dihydroxy-6-methylbenzaldehyde	Investigative	11530057	C20H28O4	332.4	CC1=CC(=C(C(=C1C=O)O)CC(C(=C)CCC2CCCCC2)O)O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BKSM14	CID 11501268	Investigative	11501268	C22H26O4	354.4	CC1=C(C(=CC=C1)C)CCC(=C)C(CC2=C(C=C(C(=C2O)C=O)C)O)O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BKY83H	Ethyl 3-(4-chlorophenyl)-4-cyano-5-propan-2-ylsulfanylthiophene-2-carboxylate	Investigative	2819763	C17H16ClNO2S2	365.9	CCOC(=O)C1=C(C(=C(S1)SC(C)C)C#N)C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BL0S5J	(7E,11E)-8,12,16-Trimethyl-5-oxoheptadeca-7,11,15-trienoic acid	Investigative	46230599	C20H32O3	320.5	CC(=CCC/C(=C/CC/C(=C/CC(=O)CCCC(=O)O)/C)/C)C	IC50 = 60000 nM	Poor binder
T13127	Farnesyl protein transferase	BL53JR	2-(1-Butyl-2-phenyl-1H-indol-3-yl)-N-isopropyl-N-pyridin-4-ylmethyl-acetamide	Investigative	44381762	C29H33N3O	439.6	CCCCN1C2=CC=CC=C2C(=C1C3=CC=CC=C3)CC(=O)N(CC4=CC=NC=C4)C(C)C	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BLB0P1	9-Methoxy-2-methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dione	Investigative	44346895	C13H12N2O3	244.25	CN1CC(=O)N2C3=C(C=C2C1=O)C(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BLD06P	(2R,3R,5S)-5-Tert-butyl-2-(4-chlorophenyl)-1-(2-methylphenyl)sulfonylpyrrolidine-3-carboxylic acid	Investigative	90665659	C22H26ClNO4S	436	CC1=CC=CC=C1S(=O)(=O)N2[C@@H](C[C@H]([C@@H]2C3=CC=C(C=C3)Cl)C(=O)O)C(C)(C)C	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BLSN10	2-(Dimethylamino)ethyl 4-(4-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-ylidene)piperidine-1-carboxylate	Investigative	13661020	C24H29N3O2	391.5	CN(C)CCOC(=O)N1CCC(=C2C3=CC=CC=C3CCC4=C2N=CC=C4)CC1	IC50 = 79000 nM	Poor binder
T13127	Farnesyl protein transferase	BM13BL	5-Chloro-2-imidazol-1-ylmethyl-2,3-dihydro-benzo[b]thiophen-3-ol	Investigative	10730506	C12H11ClN2OS	266.75	C1=CC2=C(C=C1Cl)C(C(S2)CN3C=CN=C3)O	IC50 ~ 75000 nM	Poor binder
T13127	Farnesyl protein transferase	BM1DJ6	[2-(2-Hydroxy-ethylsulfanyl)-phenyl]-[1-(3H-imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-methanone	Investigative	10552882	C28H28N4O2S	484.6	C1CN(C2=C(CN1C(=O)C3=CC=CC=C3SCCO)C=C(C=C2)C4=CC=CC=C4)CC5=CN=CN5	IC50 = 124000 nM	Poor binder
T13127	Farnesyl protein transferase	BN23BR	CID 44359346	Investigative	44359346	C24H30O6	414.5	C[C@H]1CC2C3CCC4=CC(=O)C=C[C@@]4(C3C(=O)C[C@@]2([C@@]15C6(COCO6)OCO5)C)C	IC50 = 96000 nM	Poor binder
T13127	Farnesyl protein transferase	BNK61T	(S)-2-[(3Ar,6R)-3-(1,5-Dimethyl-hexyl)-3a,6-dimethyl-7-oxo-dodecahydro-cyclopenta[a]naphthalen-6-ylmethyl]-succinic acid 4-ethyl ester	Investigative	44359406	C30H50O5	490.7	CCOC(=O)C[C@H](C[C@@]1(C2CC[C@]3(C(C2CCC1=O)CCC3C(C)CCCC(C)C)C)C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BNXH37	Ggti-2418	Investigative	11539477	C23H31N5O4	441.5	CC1=C(N=CN1)CN2CCN([C@H](C2=O)CC3=CC=CC=C3)C(=O)N[C@@H](CC(C)C)C(=O)O	IC50 = 53000 nM	Poor binder
T13127	Farnesyl protein transferase	BO2TQ0	[7-Cyclohexyl-1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone	Investigative	10624014	C30H32N4O	464.6	C1CCC(CC1)C2=CC3=C(C=C2)N(CCN(C3)C(=O)C4=CC=CC5=CC=CC=C54)CC6=CN=CN6	IC50 = 186000 nM	Poor binder
T13127	Farnesyl protein transferase	BO3D1Z	3-((3As,6R)-3-Acetyl-3a,6-dimethyl-5,7-dioxo-dodecahydro-cyclopenta[a]naphthalen-6-yl)-propionic acid	Investigative	44359604	C20H28O5	348.4	CC(=O)C1CCC2[C@@]1(CC(=O)C3C2CCC(=O)[C@]3(C)CCC(=O)O)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BOI52U	[1-(3H-Imidazol-4-ylmethyl)-7-pyridin-3-yl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone	Investigative	10742589	C29H25N5O	459.5	C1CN(C2=C(CN1C(=O)C3=CC=CC4=CC=CC=C43)C=C(C=C2)C5=CN=CC=C5)CC6=CN=CN6	IC50 = 145000 nM	Poor binder
T13127	Farnesyl protein transferase	BP13SG	2-[2-Hydroxy-3-methylidene-5-[(1S,6S)-2,2,6-trimethylcyclohexyl]pentyl]-5-methylbenzene-1,3-diol	Investigative	53324228	C22H34O3	346.5	C[C@H]1CCCC([C@H]1CCC(=C)C(CC2=C(C=C(C=C2O)C)O)O)(C)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BPD32U	Ethyl 3-(4-chlorophenyl)-4-cyano-5-[[2-(1H-imidazol-5-yl)acetyl]amino]thiophene-2-carboxylate	Investigative	127040863	C19H15ClN4O3S	414.9	CCOC(=O)C1=C(C(=C(S1)NC(=O)CC2=CN=CN2)C#N)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BPIH31	4-Cyano-3-(3,4-dimethoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylic acid	Investigative	90667628	C17H17NO4S2	363.5	CC(C)SC1=C(C(=C(S1)C(=O)O)C2=CC(=C(C=C2)OC)OC)C#N	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BPL81R	(S)-4-Methylsulfanyl-2-{3-[(4-nitro-benzylamino)-methyl]-benzoylamino}-butyric acid	Investigative	44302675	C20H23N3O5S	417.5	CSCC[C@@H](C(=O)O)NC(=O)C1=CC=CC(=C1)CNCC2=CC=C(C=C2)[N+](=O)[O-]	IC50 = 80000 nM	Poor binder
T13127	Farnesyl protein transferase	BPO3B9	9-Methoxy-2-methyl-2,3,10,10a-tetrahydro-pyrazino[1,2-a]indole-1,4-dione	Investigative	44347007	C13H14N2O3	246.26	CN1CC(=O)N2C(C1=O)CC3=C2C=CC=C3OC	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BQ1A6F	CID 23633300	Investigative	23633300	C22H32O4	360.5	C[C@@H]1CCC(=O)[C@@H]([C@@]1(C)CCC(=C)C(CC2=C(C=C(C=C2O)C)O)O)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BQC38A	(S)-2-{3-[((R)-2-Benzyloxycarbonylamino-3-benzyloxycarbonylsulfanyl-propionylamino)-methyl]-benzoylamino}-4-methylsulfanyl-butyric acid methyl ester	Investigative	44320337	C33H37N3O8S2	667.8	COC(=O)[C@H](CCSC)NC(=O)C1=CC=CC(=C1)CNC(=O)[C@H](CSC(=O)OCC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BQH38D	Ethyl 4-cyano-3-phenoxy-5-propan-2-ylsulfanylthiophene-2-carboxylate	Investigative	90667645	C17H17NO3S2	347.5	CCOC(=O)C1=C(C(=C(S1)SC(C)C)C#N)OC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BR56ZU	[(2S,10R,13R)-17-(1,5-Dimethyl-hexyl)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-2-yl]-acetic acid	Investigative	44359642	C29H46O3	442.7	CC(C)CCCC(C)C1CCC2[C@@]1(CCC3C2CCC4=CC(=O)[C@@H](C[C@]34C)CC(=O)O)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BS15EP	(S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldisulfanyl-propionylamino)-methyl]-3-benzyloxy-tetrahydro-pyran-2-carbonyl}-amino)-4-methyl-pentanoic acid	Investigative	11261604	C27H43N3O6S2	569.8	CC(C)C[C@@H](C(=O)O)NC(=O)[C@@H]1[C@H](CC[C@@H](O1)CNC(=O)[C@H](CSSC(C)(C)C)N)OCC2=CC=CC=C2	IC50 = 57000 nM	Poor binder
T13127	Farnesyl protein transferase	BTD8V6	3-Benzyldisulfanyl-9-methoxy-2-methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dione	Investigative	44346735	C20H18N2O3S2	398.5	CN1C(C(=O)N2C3=C(C=C2C1=O)C(=CC=C3)OC)SSCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BTL7E2	Methyl (2S)-2-[[(2S,3R)-3-methyl-2-[[(2S)-3-methyl-2-[[(2R)-2-(phenylmethoxycarbonylamino)-3-phenylmethoxycarbonylsulfanylpropanoyl]amino]butanoyl]amino]pentanoyl]amino]-4-methylsulfanylbutanoate	Investigative	56675646	C36H50N4O9S2	746.9	CC[C@@H](C)[C@@H](C(=O)N[C@@H](CCSC)C(=O)OC)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CSC(=O)OCC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2	IC50 = 90000 nM	Poor binder
T13127	Farnesyl protein transferase	BTQ6E0	4-{[(4-Cyanophenyl)(1-methyl-1H-imidazol-5-yl)methoxy]methyl}-3-(3-methoxyphenyl)benzoic acid	Investigative	11775366	C27H23N3O4	453.5	CN1C=NC=C1C(C2=CC=C(C=C2)C#N)OCC3=C(C=C(C=C3)C(=O)O)C4=CC(=CC=C4)OC	IC50 = 83176.38 nM	Poor binder
T13127	Farnesyl protein transferase	BU5FB1	CID 44359351	Investigative	44359351	C24H30O6	414.5	C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@@]4(C3C(=O)C[C@@]2([C@@]15C6(COCO6)OCO5)C)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BU9Z7N	3-[(E,E)-3,7,11-Trimethyl-2,6,10-dodecatrienylamino]-3-oxo-propionic acid	Investigative	10402973	C18H29NO3	307.4	CC(=CCC/C(=C/CC/C(=C/CNC(=O)CC(=O)O)/C)/C)C	IC50 = 115000 nM	Poor binder
T13127	Farnesyl protein transferase	BUB40W	2,4-Dihydroxy-3-(2-hydroxy-3-methylbut-3-enyl)-6-methylbenzaldehyde	Investigative	53322673	C13H16O4	236.26	CC1=CC(=C(C(=C1C=O)O)CC(C(=C)C)O)O	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BUHX62	2-Hydroxy-3-[2-hydroxy-3-methylidene-5-[(1S,6S)-2,2,6-trimethylcyclohexyl]pentyl]-4-methoxy-6-methylbenzaldehyde	Investigative	53317633	C24H36O4	388.5	C[C@H]1CCCC([C@H]1CCC(=C)C(CC2=C(C=C(C(=C2O)C=O)C)OC)O)(C)C	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BW0DR9	Methyl (2S)-2-[[(3S)-2-[2-[2-[2-[[2-[(3S)-3-[[(2S)-1-methoxy-4-methylsulfanyl-1-oxobutan-2-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-[(2-methylpropan-2-yl)oxycarbonyl]amino]ethyldisulfanyl]ethyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]-4-methylsulfanylbutanoate	Investigative	44323747	C50H72N6O12S4	1077.4	CC(C)(C)OC(=O)N(CCSSCCN(CC(=O)N1CC2=CC=CC=C2C[C@H]1C(=O)N[C@@H](CCSC)C(=O)OC)C(=O)OC(C)(C)C)CC(=O)N3CC4=CC=CC=C4C[C@H]3C(=O)N[C@@H](CCSC)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T13127	Farnesyl protein transferase	BW5EO9	(8E,12E)-9,13,17-Trimethyl-5-oxooctadeca-8,12,16-trienoic acid	Investigative	46230631	C21H34O3	334.5	CC(=CCC/C(=C/CC/C(=C/CCC(=O)CCCC(=O)O)/C)/C)C	IC50 = 60000 nM	Poor binder
T13127	Farnesyl protein transferase	BX8MN4	2-[2-[2-[(10R,13S,17R)-17-Hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-2-oxoethyl]butanedioic acid	Investigative	44359339	C27H34O10	518.6	C[C@]12CCC(=O)C=C1CCC3C2C(=O)C[C@]4(C3CC[C@@]4(C(=O)COC(=O)CC(CC(=O)O)C(=O)O)O)C	IC50 = 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BXD0T3	[(3Z)-4-[4-(Dimethylamino)pyridin-1-ium-1-yl]-2-ethoxycarbonyl-5-oxo-5-(3-oxo-4H-1,4-benzoxazin-6-yl)penta-1,3-dienylidene]azanide	Investigative	136254456	C23H22N4O5	434.4	CCOC(=O)C(=C=[N-])/C=C(/C(=O)C1=CC2=C(C=C1)OCC(=O)N2)\\[N+]3=CC=C(C=C3)N(C)C	IC50 = 55220 nM	Poor binder
T13127	Farnesyl protein transferase	BXY80I	(S)-4-Methyl-2-({4-[(pyridin-4-ylmethyl)-amino]-biphenyl-2-carbonyl}-amino)-pentanoic acid	Investigative	11796226	C25H27N3O3	417.5	CC(C)C[C@@H](C(=O)O)NC(=O)C1=C(C=CC(=C1)NCC2=CC=NC=C2)C3=CC=CC=C3	IC50 = 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BXZ3S6	(2S)-3-Hydroxy-2-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-[(4-phenylmethoxybenzoyl)amino]butanoyl]amino]pentanoyl]amino]propanoic acid	Investigative	44298943	C28H37N3O7	527.6	CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)C1=CC=C(C=C1)OCC2=CC=CC=C2	IC50 = 166000 nM	Poor binder
T13127	Farnesyl protein transferase	BY08NK	2-Ethyl-butyric acid 2-((10R,13S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester	Investigative	44359702	C27H38O6	458.6	CCC(CC)C(=O)OCC(=O)[C@]1(CCC2[C@@]1(CC(=O)C3C2CCC4=CC(=O)CC[C@]34C)C)O	IC50 = 56000 nM	Poor binder
T13127	Farnesyl protein transferase	BY9U7K	Ethyl 4-cyano-3-(2-hydroxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylate	Investigative	90667621	C17H17NO3S2	347.5	CCOC(=O)C1=C(C(=C(S1)SC(C)C)C#N)C2=CC=CC=C2O	IC50 ~ 50000 nM	Poor binder
T13127	Farnesyl protein transferase	BZB9I1	[1-(3H-Imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-(2-methoxy-naphthalen-1-yl)-methanone	Investigative	10719802	C31H28N4O2	488.6	COC1=C(C2=CC=CC=C2C=C1)C(=O)N3CCN(C4=C(C3)C=C(C=C4)C5=CC=CC=C5)CC6=CN=CN6	IC50 = 58000 nM	Poor binder
T13127	Farnesyl protein transferase	BZX81E	Ethyl 4-cyano-3-(4-methoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylate	Investigative	90667612	C18H19NO3S2	361.5	CCOC(=O)C1=C(C(=C(S1)SC(C)C)C#N)C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder