TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T15068	Focal adhesion kinase 1	D0E6XR	Dasatinib	Approved	3062316	C22H26ClN7O2S	488	CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO	IC50 ~ 50000 nM	Poor binder
T15068	Focal adhesion kinase 1	B0WLH8	N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide	Investigative	58056356	C17H12N4O2S	336.4	COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43	IC50 ~ 50000 nM	Poor binder
T15068	Focal adhesion kinase 1	B1A4EI	(8S,16S)-3,16-Dihydroxy-9,10-seco-1,3,5(10)-cholestatrien-9-one	Investigative	9547398	C27H42O3	414.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3C[C@@H]([C@@H]([C@]3(CCC2=O)C)[C@H](C)CCCC(C)C)O	IC50 ~ 100000 nM	Poor binder
T15068	Focal adhesion kinase 1	B2EX3Y	4-(1-Methylbenzimidazol-2-yl)-N-(4-methylphenyl)pyrimidin-2-amine	Investigative	60165994	C19H17N5	315.4	CC1=CC=C(C=C1)NC2=NC=CC(=N2)C3=NC4=CC=CC=C4N3C	IC50 = 58000 nM	Poor binder
T15068	Focal adhesion kinase 1	B3QF8S	N-{5-[(3,4-Difluorophenyl)methyl]-1,3-thiazol-2-yl}-3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanamide	Investigative	135886762	C21H16F2N4O2S	426.4	C1=CC=C2C(=C1)C(=O)NC(=N2)CCC(=O)NC3=NC=C(S3)CC4=CC(=C(C=C4)F)F	IC50 ~ 50000 nM	Poor binder
T15068	Focal adhesion kinase 1	B43WPI	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325478	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T15068	Focal adhesion kinase 1	B58TMC	[6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate	Investigative	24753787	C21H22ClN3O6S	479.9	CC1=C(C(=O)OC2=CC(=C(C=C12)Cl)OC(=O)N(C)C)CC3=CC(=CC=C3)NS(=O)(=O)NC	IC50 ~ 50000 nM	Poor binder
T15068	Focal adhesion kinase 1	B5J9TO	N-[2-[[4-(Trifluoromethyl)-6-(3,4,5-trimethoxyanilino)-1,3,5-triazin-2-yl]amino]phenyl]acetamide	Investigative	71813495	C21H21F3N6O4	478.4	CC(=O)NC1=CC=CC=C1NC2=NC(=NC(=N2)C(F)(F)F)NC3=CC(=C(C(=C3)OC)OC)OC	IC50 = 125600 nM	Poor binder
T15068	Focal adhesion kinase 1	B5JKD1	N-(4-Chlorophenyl)-4-(1-methylbenzimidazol-2-yl)pyrimidin-2-amine	Investigative	60165995	C18H14ClN5	335.8	CN1C2=CC=CC=C2N=C1C3=NC(=NC=C3)NC4=CC=C(C=C4)Cl	IC50 = 69000 nM	Poor binder
T15068	Focal adhesion kinase 1	B7N1WR	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325479	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T15068	Focal adhesion kinase 1	B7NCE8	N-(5-(6,7-Dimethoxyquinolin-4-yloxy)pyridin-2-yl)-4-(4-methylpiperazin-1-yl)-2-oxo-1-phenyl-1,2-dihydropyridine-3-carboxamide	Investigative	45274824	C33H32N6O5	592.6	CN1CCN(CC1)C2=C(C(=O)N(C=C2)C3=CC=CC=C3)C(=O)NC4=NC=C(C=C4)OC5=C6C=C(C(=CC6=NC=C5)OC)OC	IC50 ~ 125000 nM	Poor binder
T15068	Focal adhesion kinase 1	B8H5BL	N-[2-[[4-Methyl-6-(3,4,5-trimethoxyanilino)-1,3,5-triazin-2-yl]amino]phenyl]acetamide	Investigative	71813332	C21H24N6O4	424.5	CC1=NC(=NC(=N1)NC2=CC(=C(C(=C2)OC)OC)OC)NC3=CC=CC=C3NC(=O)C	IC50 = 50800 nM	Poor binder
T15068	Focal adhesion kinase 1	B8UTR6	N-(5-(6,7-Dimethoxyquinolin-4-yloxy)pyridin-2-yl)-2-oxo-1-phenyl-5-(thiophen-2-yl)-1,2-dihydropyridine-3-carboxamide	Investigative	45275055	C32H24N4O5S	576.6	COC1=CC2=C(C=CN=C2C=C1OC)OC3=CN=C(C=C3)NC(=O)C4=CC(=CN(C4=O)C5=CC=CC=C5)C6=CC=CS6	IC50 ~ 125000 nM	Poor binder
T15068	Focal adhesion kinase 1	B9MUI8	N-(5-(6,7-Dimethoxyquinolin-4-yloxy)pyridin-2-yl)-4-(dimethylamino)-2-oxo-1-phenyl-1,2-dihydropyridine-3-carboxamide	Investigative	45274936	C30H27N5O5	537.6	CN(C)C1=C(C(=O)N(C=C1)C2=CC=CC=C2)C(=O)NC3=NC=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OC)OC	IC50 ~ 125000 nM	Poor binder
T15068	Focal adhesion kinase 1	B9OM7T	N-[2-[[4-(Methylamino)-6-(3,4,5-trimethoxyanilino)-1,3,5-triazin-2-yl]amino]phenyl]methanesulfonamide	Investigative	71813329	C20H25N7O5S	475.5	CNC1=NC(=NC(=N1)NC2=CC(=C(C(=C2)OC)OC)OC)NC3=CC=CC=C3NS(=O)(=O)C	IC50 = 65900 nM	Poor binder
T15068	Focal adhesion kinase 1	B9PUY2	N-[3-[[4-Chloro-6-(3,4,5-trimethoxyanilino)-1,3,5-triazin-2-yl]amino]phenyl]methanesulfonamide	Investigative	73350669	C19H21ClN6O5S	480.9	COC1=CC(=CC(=C1OC)OC)NC2=NC(=NC(=N2)NC3=CC(=CC=C3)NS(=O)(=O)C)Cl	IC50 = 57800 nM	Poor binder
T15068	Focal adhesion kinase 1	BCB0J7	N-(5-(6,7-Dimethoxyquinolin-4-yloxy)pyridin-2-yl)-2-oxo-1-phenyl-5-(pyridin-3-yl)-1,2-dihydropyridine-3-carboxamide	Investigative	45275165	C33H25N5O5	571.6	COC1=CC2=C(C=CN=C2C=C1OC)OC3=CN=C(C=C3)NC(=O)C4=CC(=CN(C4=O)C5=CC=CC=C5)C6=CN=CC=C6	IC50 ~ 125000 nM	Poor binder
T15068	Focal adhesion kinase 1	BDK9R0	Calicoferol C	Investigative	10024683	C28H44O2	412.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3CC[C@@H]([C@]3(CC[C@H]2O)C)[C@H](C)CCC(=C)C(C)C	IC50 ~ 100000 nM	Poor binder
T15068	Focal adhesion kinase 1	BDUX80	N-(5-(7-Methoxyquinolin-4-yloxy)pyridin-2-yl)-2-oxo-1-phenyl-5-(pyrazin-2-yl)-1,2-dihydropyridine-3-carboxamide	Investigative	45275166	C31H22N6O4	542.5	COC1=CC2=NC=CC(=C2C=C1)OC3=CN=C(C=C3)NC(=O)C4=CC(=CN(C4=O)C5=CC=CC=C5)C6=NC=CN=C6	IC50 ~ 125000 nM	Poor binder
T15068	Focal adhesion kinase 1	BF32AR	Calicoferol B	Investigative	10047545	C27H44O3	416.6	CC1=C(C=C(C=C1)O)CC[C@@H]2[C@@H](CC[C@]3([C@H]2C[C@@H]([C@@H]3[C@H](C)CCCC(C)C)O)C)O	IC50 ~ 100000 nM	Poor binder
T15068	Focal adhesion kinase 1	BF51YV	3,5-Dihydro[1,2,4]triazino[3,4-C][1,4]benzoxazin-2(1h)-One	Investigative	3071991	C10H9N3O2	203.2	C1C(=O)NN=C2N1C3=CC=CC=C3OC2	IC50 = 156000 nM	Poor binder
T15068	Focal adhesion kinase 1	BJ57YZ	N-(4-Methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine	Investigative	50908681	C19H16N2O2	304.3	COC1=CC=C(C=C1)CNC2=C3C4=CC=CC=C4OC3=NC=C2	IC50 = 194000 nM	Poor binder
T15068	Focal adhesion kinase 1	BNR17Z	3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one	Investigative	24894883	C22H22N2O4	378.4	CN1C=C(C2=CC=CC=C21)C3=C(CNC3=O)C4=CC(=C(C(=C4)OC)OC)OC	IC50 = 50000 nM	Poor binder
T15068	Focal adhesion kinase 1	BR0E6X	1,1-Dimethyl-3-[2-[[4-methyl-6-(3,4,5-trimethoxyanilino)-1,3,5-triazin-2-yl]amino]phenyl]urea	Investigative	71813494	C22H27N7O4	453.5	CC1=NC(=NC(=N1)NC2=CC(=C(C(=C2)OC)OC)OC)NC3=CC=CC=C3NC(=O)N(C)C	IC50 = 54300 nM	Poor binder
T15068	Focal adhesion kinase 1	BR43PL	4-(2-Methoxyethylamino)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-2-oxo-1-phenyl-1,2-dihydropyridine-3-carboxamide	Investigative	11963310	C30H27N5O5	537.6	COCCNC1=C(C(=O)N(C=C1)C2=CC=CC=C2)C(=O)NC3=NC=C(C=C3)OC4=C5C=CC(=CC5=NC=C4)OC	IC50 ~ 125000 nM	Poor binder
T15068	Focal adhesion kinase 1	BSI9C1	N-(5-(7-Methoxyquinolin-4-yloxy)pyridin-2-yl)-2-oxo-1-phenyl-5-(pyridin-3-yl)-1,2-dihydropyridine-3-carboxamide	Investigative	45275054	C32H23N5O4	541.6	COC1=CC2=NC=CC(=C2C=C1)OC3=CN=C(C=C3)NC(=O)C4=CC(=CN(C4=O)C5=CC=CC=C5)C6=CN=CC=C6	IC50 ~ 125000 nM	Poor binder
T15068	Focal adhesion kinase 1	BV9WQ8	N-(4-Ethoxyphenyl)-4-(1-methylbenzimidazol-2-yl)pyrimidin-2-amine	Investigative	60166136	C20H19N5O	345.4	CCOC1=CC=C(C=C1)NC2=NC=CC(=N2)C3=NC4=CC=CC=C4N3C	IC50 ~ 100000 nM	Poor binder
T15068	Focal adhesion kinase 1	BVRH01	1-Benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-4-(methylamino)-2-oxo-1,2-dihydropyridine-3-carboxamide	Investigative	45274615	C30H27N5O5	537.6	CNC1=C(C(=O)N(C=C1)CC2=CC=CC=C2)C(=O)NC3=NC=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OC)OC	IC50 ~ 125000 nM	Poor binder
T15068	Focal adhesion kinase 1	BVW47M	1,3-Dimethyl-7-(1-methylbenzimidazol-2-yl)pyrido[2,3-d]pyrimidine-2,4-dione	Investigative	60165992	C17H15N5O2	321.33	CN1C2=CC=CC=C2N=C1C3=NC4=C(C=C3)C(=O)N(C(=O)N4C)C	IC50 = 92000 nM	Poor binder
T15068	Focal adhesion kinase 1	BXU03W	2-{[(5-{[(Oxolan-2-yl)methyl]amino}-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-6-phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one	Investigative	17549086	C20H19N5O2S3	457.6	C1CC(OC1)CNC2=NN=C(S2)SCC3=NC4=C(C=C(S4)C5=CC=CC=C5)C(=O)N3	IC50 ~ 50000 nM	Poor binder
T15068	Focal adhesion kinase 1	BY7MP5	5-(1H-Indol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazin-2-one	Investigative	118723185	C21H19N3O4	377.4	COC1=CC(=CC(=C1OC)OC)C2=NC(=CNC2=O)C3=CNC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T15068	Focal adhesion kinase 1	BZR76B	Norlichexanthone	Investigative	5281657	C14H10O5	258.23	CC1=CC(=CC2=C1C(=O)C3=C(C=C(C=C3O2)O)O)O	IC50 ~ 100000 nM	Poor binder
T15068	Focal adhesion kinase 1	D0YZ7H	JNJ-10198409	Investigative	9797370	C18H16FN3O2	325.3	COC1=C(C=C2C(=C1)CC3=C2NN=C3NC4=CC(=CC=C4)F)OC	IC50 ~ 100000 nM	Poor binder