TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T15497	Prostaglandin E2 receptor EP1	B0CSQ4	4-(2-((R)-2-((S)-3-Hydroxyoct-1-enyl)-5-oxopyrrolidin-1-yl)ethyl)benzoate	Investigative	10291963	C21H29NO4	359.5	CCCCC[C@@H](/C=C/[C@H]1CCC(=O)N1CCC2=CC=C(C=C2)C(=O)O)O	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	B2L6AG	(E)-3-[2-(4-Methylsulfanyl-benzyl)-phenyl]-acrylic acid	Investigative	9817292	C17H16O2S	284.4	CSC1=CC=C(C=C1)CC2=CC=CC=C2/C=C/C(=O)O	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	B2PXE5	3-(2-((6-(Benzyloxy)naphthalen-2-yl)methyl)phenyl)acrylic acid	Investigative	21198692	C27H22O3	394.5	C1=CC=C(C=C1)COC2=CC3=C(C=C2)C=C(C=C3)CC4=CC=CC=C4/C=C/C(=O)O	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	B2VGU9	2-[1-[2-(N-Benzoyl-4-methylanilino)ethyl]piperidin-4-yl]oxyacetic acid	Investigative	127029417	C23H28N2O4	396.5	CC1=CC=C(C=C1)N(CCN2CCC(CC2)OCC(=O)O)C(=O)C3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	B5EGR7	(E)-3-(2-{3-[2-(Phenylmethoxy)phenyl]phenyl}phenyl)prop-2-enoic acid	Investigative	12112238	C28H22O3	406.5	C1=CC=C(C=C1)COC2=CC=CC=C2C3=CC=CC(=C3)C4=CC=CC=C4/C=C/C(=O)O	Ki = 72000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	B61TJN	N-(2-Thienylsulfonyl)-3'-(methylsulfonyl)biphenyl-2-propionamide	Investigative	21362869	C20H19NO5S3	449.6	CS(=O)(=O)C1=CC=CC(=C1)C2=CC=CC=C2CCC(=O)NS(=O)(=O)C3=CC=CS3	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	B9PW2J	(E)-3-[2-(3,4-Dichloro-benzyl)-phenyl]-acrylic acid	Investigative	10402929	C16H12Cl2O2	307.2	C1=CC=C(C(=C1)CC2=CC(=C(C=C2)Cl)Cl)/C=C/C(=O)O	Ki = 63000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BCHX02	{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenylamino}-acetic acid	Investigative	44349551	C25H21NO3S	415.5	C1=CC=C(C=C1)COC2=CC=CC=C2C3=CC(=CS3)C4=CC=CC=C4NCC(=O)O	Ki = 85000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BE1VH6	(E)-3-[2-[(E)-3-[4-[2-[4-[(1E,3E)-4-[4-(Dimethylamino)phenyl]buta-1,3-dienyl]-2,6-dimethylpyridin-1-ium-1-yl]ethoxy]-3-methoxyphenyl]prop-1-enyl]phenyl]prop-2-enoic acid;tetrafluoroborate	Investigative	71458757	C40H43BF4N2O4	702.6	[B-](F)(F)(F)F.CC1=CC(=CC(=[N+]1CCOC2=C(C=C(C=C2)C/C=C/C3=CC=CC=C3/C=C/C(=O)O)OC)C)/C=C/C=C/C4=CC=C(C=C4)N(C)C	Ki = 68625 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BEZV80	(E)-3-{2-[(E)-3-(2-Hydroxy-3-methyl-phenyl)-allyl]-phenyl}-acrylic acid	Investigative	9965922	C19H18O3	294.3	CC1=C(C(=CC=C1)/C=C/CC2=CC=CC=C2/C=C/C(=O)O)O	Ki = 68000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BI2PJ9	7-{(R)-2-[(E)-3-Hydroxy-3-(3-phenoxy-phenyl)-propenyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid	Investigative	44290494	C26H31NO5	437.5	C1CC(=O)N([C@H]1/C=C/C(C2=CC(=CC=C2)OC3=CC=CC=C3)O)CCCCCCC(=O)O	Ki = 50000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BI8TE2	3-(2-((E)-3-(4-(Benzyloxy)-3-methoxyphenyl)prop-1-enyl)phenyl)acrylic acid	Investigative	10157810	C26H24O4	400.5	COC1=C(C=CC(=C1)C/C=C/C2=CC=CC=C2/C=C/C(=O)O)OCC3=CC=CC=C3	Ki = 151350 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BK7LX0	7-{(R)-2-[(E)-3-Hydroxy-4-(3-trifluoromethyl-phenyl)-but-1-enyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid	Investigative	44289792	C22H28F3NO4	427.5	C1CC(=O)N([C@H]1/C=C/C(CC2=CC(=CC=C2)C(F)(F)F)O)CCCCCCC(=O)O	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BR0C6K	(E)-3-[2-(2,4-Dichloro-benzyl)-phenyl]-acrylic acid	Investigative	44377464	C16H12Cl2O2	307.2	C1=CC=C(C(=C1)CC2=C(C=C(C=C2)Cl)Cl)/C=C/C(=O)O	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BR8VW6	3-(2-((6-(Benzyloxy)naphthalen-2-yl)methyl)phenyl)-N-(5-bromo-2-methoxyphenylsulfonyl)acrylamide	Investigative	15551228	C34H28BrNO5S	642.6	COC1=C(C=C(C=C1)Br)S(=O)(=O)NC(=O)/C=C/C2=CC=CC=C2CC3=CC4=C(C=C3)C=C(C=C4)OCC5=CC=CC=C5	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BS5ZN1	7-{(R)-2-[(E)-(S)-3-Hydroxy-4-(3-trifluoromethyl-phenyl)-but-1-enyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid	Investigative	10202765	C22H28F3NO4	427.5	C1CC(=O)N([C@H]1/C=C/[C@H](CC2=CC(=CC=C2)C(F)(F)F)O)CCCCCCC(=O)O	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BSR43T	Schembl20719106	Investigative	49850345	C21H18N2O4	362.4	CC(C)C1(C(=O)NC(=O)O1)C2=CC=C(NC2=O)C3=CC4=CC=CC=C4C=C3	Ki ~ 50118.72 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BV9AM7	1-Benzyl-1-[2-[4-[(6-oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(2-phenylethyl)urea	Investigative	15491230	C44H39N3O4S	705.9	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)N(CC6=CC=CC=C6)C(=O)NCCC7=CC=CC=C7	Ki = 51000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	BWNO89	4''-(Benzyloxy)-1,1':3',1''-terbenzene-2-propionic acid	Investigative	21362863	C28H24O3	408.5	C1=CC=C(C=C1)COC2=CC=C(C=C2)C3=CC(=CC=C3)C4=CC=CC=C4CCC(=O)O	Ki ~ 97000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	D02LXJ	3-(2-cinnamylphenyl)acrylic acid	Investigative	9813912	C18H16O2	264.3	C1=CC=C(C=C1)/C=C/CC2=CC=CC=C2/C=C/C(=O)O	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	D02SAD	3-(2-(4-methoxycinnamyl)phenyl)acrylic acid	Investigative	44419388	C19H18O3	294.3	COC1=CC=C(C=C1)/C=C/CC2=CC=CC=C2/C=C/C(=O)O	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	D07JMB	8-aza-11-deoxyprostaglandin E1	Investigative	44289922	C19H33NO4	339.5	CCCCC[C@@H](/C=C/[C@H]1CCC(=O)N1CCCCCCC(=O)O)O	Ki ~ 100000 nM	Poor binder
T15497	Prostaglandin E2 receptor EP1	D0Z3XJ	3-(2-(naphthalen-2-ylmethyl)phenyl)acrylic acid	Investigative	9817405	C20H16O2	288.3	C1=CC=C2C=C(C=CC2=C1)CC3=CC=CC=C3/C=C/C(=O)O	Ki ~ 100000 nM	Poor binder