TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T15797 SET and MYND domain-containing protein 2 B1QW2K N-((1R,3r,5S)-8-((4-(Benzylamino)piperidin-1-yl)sulfonyl)-8-azabicyclo[3.2.1]octan-3-yl)-6-chloro-2-oxoindoline-5-carboxamide Investigative 118946368 C28H34ClN5O4S 572.1 C1C[C@H]2CC(C[C@@H]1N2S(=O)(=O)N3CCC(CC3)NCC4=CC=CC=C4)NC(=O)C5=C(C=C6C(=C5)CC(=O)N6)Cl IC50 ~ 50000 nM Poor binder T15797 SET and MYND domain-containing protein 2 B29ZVO 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine Investigative 78357767 C23H35N5O2 413.6 COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCCCCN4CCCC4)OC IC50 ~ 100000 nM Poor binder T15797 SET and MYND domain-containing protein 2 B8D9YH (2~{S})-5-[2-(3-Aminocarbonylphenyl)ethyl-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]amino]-2-azanyl-pentanoic acid Investigative 134159782 C24H32N8O6 528.6 C1=CC(=CC(=C1)C(=O)N)CCN(CCC[C@@H](C(=O)O)N)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O IC50 = 62000 nM Poor binder T15797 SET and MYND domain-containing protein 2 BRH94C 6-Chloro-2-oxo-N-((1R,3r,5S)-8-(((1-(4,4,4-trifluorobutyl)piperidin-4-yl)methyl)sulfonyl)-8-azabicyclo[3.2.1]octan-3-yl)indoline-5-carboxamide Investigative 118946372 C26H34ClF3N4O4S 591.1 C1C[C@H]2CC(C[C@@H]1N2S(=O)(=O)CC3CCN(CC3)CCCC(F)(F)F)NC(=O)C4=C(C=C5C(=C4)CC(=O)N5)Cl IC50 ~ 50000 nM Poor binder