TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T16016	C-C chemokine receptor type 1	B0H2XD	2,2'-Bipyridine	Investigative	1474	C10H8N2	156.18	C1=CC=NC(=C1)C2=CC=CC=N2	IC50 = 125892.54 nM	Poor binder
T16016	C-C chemokine receptor type 1	B2FWC9	1-(4-Phenylbutyl)-4-benzylpiperidine	Investigative	11722772	C22H29N	307.5	C1CN(CCC1CC2=CC=CC=C2)CCCCC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B2GK3C	5-Methyl-1,10-phenanthroline	Investigative	72791	C13H10N2	194.23	CC1=CC2=C(C3=C1C=CC=N3)N=CC=C2	IC50 = 119000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B35PJC	1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(2,5-difluoro-phenyl)-urea	Investigative	10928228	C26H27F2N3O	435.5	C1CN(CCC1CC2=CC=CC=C2)CC3=CC=CC=C3NC(=O)NC4=C(C=CC(=C4)F)F	IC50 ~ 50000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B3ULC5	4,4'-Dimethyl-2,2'-bipyridine	Investigative	14338	C12H12N2	184.24	CC1=CC(=NC=C1)C2=NC=CC(=C2)C	IC50 = 100000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B3YW2H	5-(4-Benzyl-piperazin-1-yl)-2,2-diphenyl-pentanenitrile	Investigative	11729258	C28H31N3	409.6	C1CN(CCN1CCCC(C#N)(C2=CC=CC=C2)C3=CC=CC=C3)CC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B43QPN	(R)-N2-(4-Methoxybenzyl)-N1-(4-chlorophenyl)-N2-methylpyrrolidine-1,2-dicarboxamide	Investigative	25231478	C21H24ClN3O3	401.9	CN(CC1=CC=C(C=C1)OC)C(=O)[C@H]2CCCN2C(=O)NC3=CC=C(C=C3)Cl	IC50 ~ 77000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B5IW0Q	(R)-N2-[4-(Trifluoromethyl)benzyl]-N1-(4-chlorophenyl)-N2-methylpyrrolidine-1,2-dicarboxamide	Investigative	25231479	C21H21ClF3N3O2	439.9	CN(CC1=CC=C(C=C1)C(F)(F)F)C(=O)[C@H]2CCCN2C(=O)NC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B5PB8T	1,10-Phenanthroline-4,7-diol	Investigative	77524	C12H8N2O2	212.2	C1=CC2=C(C3=C1C(=O)C=CN3)NC=CC2=O	EC50 ~ 100000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B6MK0J	2,2':6',2''-Terpyridine	Investigative	70848	C15H11N3	233.27	C1=CC=NC(=C1)C2=NC(=CC=C2)C3=CC=CC=N3	EC50 = 63095.73 nM	Poor binder
T16016	C-C chemokine receptor type 1	B72PXT	(R)-N2-(4-Chloro-2-methylbenzyl)-N1-(4-chlorophenyl)-N2-methylpyrrolidine-1,2-dicarboxamide	Investigative	25231482	C21H23Cl2N3O2	420.3	CC1=C(C=CC(=C1)Cl)CN(C)C(=O)[C@H]2CCCN2C(=O)NC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B8DW7C	1,4-Dibenzylpiperidine	Investigative	10934382	C19H23N	265.4	C1CN(CCC1CC2=CC=CC=C2)CC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B91PLB	1,10-Phenanthroline	Investigative	1318	C12H8N2	180.2	C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1	IC50 = 74000 nM	Poor binder
T16016	C-C chemokine receptor type 1	B9L3XU	Abametapir	Investigative	15664	C12H12N2	184.24	CC1=CN=C(C=C1)C2=NC=C(C=C2)C	IC50 = 199526.23 nM	Poor binder
T16016	C-C chemokine receptor type 1	BG9DA1	(R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoromethyl)phenyl]azetidine-1,2-dicarboxamide	Investigative	25233758	C20H19ClF3N3O2	425.8	CN(CC1=CC=C(C=C1)Cl)C(=O)[C@H]2CCN2C(=O)NC3=CC=C(C=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T16016	C-C chemokine receptor type 1	BH95OT	4,7-Dimethyl-1,10-phenanthroline	Investigative	72792	C14H12N2	208.26	CC1=C2C=CC3=C(C=CN=C3C2=NC=C1)C	IC50 = 100000 nM	Poor binder
T16016	C-C chemokine receptor type 1	BI07YX	(R)-N2-(3-Chlorobenzyl)-N1-(4-chlorophenyl)-N2-(2-hydroxyethyl)pyrrolidine-1,2-dicarboxamide	Investigative	25231303	C21H23Cl2N3O3	436.3	C1C[C@@H](N(C1)C(=O)NC2=CC=C(C=C2)Cl)C(=O)N(CCO)CC3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T16016	C-C chemokine receptor type 1	BJ54HO	N-[(2S,3S,5R)-5-Carbamoyl-7-(dimethylamino)-3-hydroxy-1-phenylheptan-2-yl]quinoxaline-2-carboxamide	Investigative	44309061	C25H31N5O3	449.5	CN(C)CC[C@H](C[C@@H]([C@H](CC1=CC=CC=C1)NC(=O)C2=NC3=CC=CC=C3N=C2)O)C(=O)N	IC50 = 55100 nM	Poor binder
T16016	C-C chemokine receptor type 1	BK8V2F	11-Butyl-3-[1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methyl-4-piperidyl]-9-[(4-ethoxycyclohexyl)methyl]-3,9-diazaspiro[5.5]undecan-10-one	Investigative	25230828	C35H57N5O3	595.9	CCCCC1C(=O)N(CCC12CCN(CC2)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C)CC5CCC(CC5)OCC	IC50 ~ 50000 nM	Poor binder
T16016	C-C chemokine receptor type 1	BL41TN	4-Benzyl-1-phenethyl-piperidine	Investigative	10591473	C20H25N	279.4	C1CN(CCC1CC2=CC=CC=C2)CCC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T16016	C-C chemokine receptor type 1	BM93CS	1-(1-Benzyl-piperidin-4-yl)-3-[2-(4-benzyl-piperidin-1-ylmethyl)-phenyl]-urea	Investigative	9935588	C32H40N4O	496.7	C1CN(CCC1CC2=CC=CC=C2)CC3=CC=CC=C3NC(=O)NC4CCN(CC4)CC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T16016	C-C chemokine receptor type 1	BN4YF8	PharmaGSID_48521	Investigative	44555481	C31H49N5O4	555.8	CCCC[C@H]1CN(C(=O)OC12CCN(CC2)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C)CC5CCOCC5	IC50 ~ 50000 nM	Poor binder
T16016	C-C chemokine receptor type 1	BU7Z9G	4,4'-Dimethoxy-2,2'-bipyridine	Investigative	2733927	C12H12N2O2	216.24	COC1=CC(=NC=C1)C2=NC=CC(=C2)OC	IC50 = 179000 nM	Poor binder
T16016	C-C chemokine receptor type 1	BV2FP5	(R)-N2-(4-Chlorobenzyl)-N1-(4-chlorophenyl)pyrrolidine-1,2-dicarboxamide	Investigative	25231298	C19H19Cl2N3O2	392.3	C1C[C@@H](N(C1)C(=O)NC2=CC=C(C=C2)Cl)C(=O)NCC3=CC=C(C=C3)Cl	IC50 ~ 75000 nM	Poor binder
T16016	C-C chemokine receptor type 1	BVE2J4	3,4,7,8-Tetramethyl-1,10-phenanthroline	Investigative	74265	C16H16N2	236.31	CC1=CN=C2C(=C1C)C=CC3=C(C(=CN=C32)C)C	IC50 = 158489.32 nM	Poor binder
T16016	C-C chemokine receptor type 1	BWN6X2	5-(4-Benzyl-piperidin-1-yl)-2,2-diphenyl-pentanenitrile	Investigative	10916572	C29H32N2	408.6	C1CN(CCC1CC2=CC=CC=C2)CCCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T16016	C-C chemokine receptor type 1	BXL70U	1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(2-piperidin-1-yl-ethyl)-urea	Investigative	11026461	C27H38N4O	434.6	C1CCN(CC1)CCNC(=O)NC2=CC=CC=C2CN3CCC(CC3)CC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder