TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T16808	Protein arginine methyltransferase 1	D05EAM	Pentamidine	Approved	4735	C19H24N4O2	340.4	C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N	IC50 = 81000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B01LJI	(2S)-2-Amino-5-[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]oxolan-2-yl]methyl-(2-iodoethyl)amino]pentanoic acid	Investigative	56642706	C18H28IN7O5	549.4	CNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CN(CCC[C@@H](C(=O)O)N)CCI)O)O	IC50 ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B0A4UL	N-(2-Methoxybenzyl)-1-(3-((2-(methylamino)ethylamino)methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide	Investigative	25216415	C23H26F3N5O2	461.5	CNCCNCC1=CC(=CC=C1)N2C(=CC(=N2)C(F)(F)F)C(=O)NCC3=CC=CC=C3OC	IC50 ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B1O0UE	2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid	Investigative	3383	C20H12O5	332.3	C1=CC=C(C(=C1)C2=C3C=CC(=O)C=C3OC4=C2C=CC(=C4)O)C(=O)O	IC50 = 75000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B29ZVO	6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine	Investigative	78357767	C23H35N5O2	413.6	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCCCCN4CCCC4)OC	IC50 ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B4RDW1	7-Hydroxy-8-((2-methoxy-5-(vinylsulfonyl)phenyl)diazenyl)naphthalene-1,3-disulfonate	Investigative	4392904	C19H16N2O10S3	528.5	COC1=C(C=C(C=C1)S(=O)(=O)C=C)N=NC2=C(C=CC3=CC(=CC(=C32)S(=O)(=O)O)S(=O)(=O)O)O	IC50 = 50500 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B4S1EU	Hexamidine	Investigative	65130	C20H26N4O2	354.4	C1=CC(=CC=C1C(=N)N)OCCCCCCOC2=CC=C(C=C2)C(=N)N	IC50 = 52000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B51HKY	4-Amino-N-(pyridin-2-ylmethyl)benzenesulfonamide	Investigative	3663787	C12H13N3O2S	263.32	C1=CC=NC(=C1)CNS(=O)(=O)C2=CC=C(C=C2)N	IC50 = 70700 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B5M6XV	N-[(4-Methylphenyl)methyl]-7H-purin-6-amine	Investigative	850964	C13H13N5	239.28	CC1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	IC50 = 89000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B5WOU4	Guanidine, 5-nitro-1H-benzimidazol-2-yl-	Investigative	3246448	C8H8N6O2	220.19	C1=CC2=C(C=C1[N+](=O)[O-])NC(=N2)N=C(N)N	IC50 = 76100 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B69BKW	N-[(3-Bromophenyl)methyl]-1-[2-(methylamino)ethyl]piperidin-4-amine	Investigative	137635057	C15H24BrN3	326.27	CNCCN1CCC(CC1)NCC2=CC(=CC=C2)Br	IC50 ~ 50000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B7XIV5	Stilbamidine	Investigative	5351747	C16H16N4	264.32	C1=CC(=CC=C1/C=C/C2=CC=C(C=C2)C(=N)N)C(=N)N	IC50 = 52000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B8IH2L	1-[3-[[(1S,2R,3S,4R)-4-(6-Aminopurin-9-yl)-2,3-dihydroxycyclopentyl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea	Investigative	76331683	C28H42N8O3	538.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2C[C@H]([C@@H]([C@@H]2O)O)N3C=NC4=C(N=CN=C43)N	Ki ~ 50000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B8VQ0F	(2S)-2-Amino-5-[[(2R,3S,4R,5R)-5-[6-(benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl-(2-iodoethyl)amino]pentanoic acid	Investigative	56642708	C24H32IN7O5	625.5	C1=CC=C(C=C1)CNC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CN(CCC[C@@H](C(=O)O)N)CCI)O)O	IC50 ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	B9SXW1	6-[(6-Carboxy-8-hydroxynaphthalen-2-yl)carbamoylamino]-4-hydroxynaphthalene-2-carboxylic acid	Investigative	46866514	C23H16N2O7	432.4	C1=CC(=CC2=C(C=C(C=C21)C(=O)O)O)NC(=O)NC3=CC4=C(C=C(C=C4C=C3)C(=O)O)O	IC50 = 95000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BC20HX	4,5-Dihydroxy-3-((8-hydroxy-3,6-disulfonatonaphthalen-1-yl)diazenyl)naphthalene-2,7-disulfonate	Investigative	103900	C20H14N2O15S4	650.6	C1=C2C=C(C=C(C2=C(C=C1S(=O)(=O)O)N=NC3=C(C4=C(C=C(C=C4C=C3S(=O)(=O)O)S(=O)(=O)O)O)O)O)S(=O)(=O)O	IC50 = 68200 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BD3X9I	N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indazole-4-carboxamide	Investigative	67466175	C29H35N7O2	513.6	CC1=CC(=C(C(=O)N1)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C)C(C)C)C	IC50 ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BE8I1R	C.I. Direct Red 23	Investigative	91330	C35H27N7O10S2	769.8	CC(=O)NC1=CC=C(C=C1)N=NC2=C(C=C3C=C(C=CC3=C2O)NC(=O)NC4=CC5=CC(=C(C(=C5C=C4)O)N=NC6=CC=CC=C6)S(=O)(=O)O)S(=O)(=O)O	IC50 = 176500 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BF1NH9	1-(4-Tert-butylphenyl)-3-[3-[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(prop-2-enylamino)purin-9-yl]oxolan-2-yl]methyl-propan-2-ylamino]propyl]urea	Investigative	70676141	C30H44N8O4	580.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)NCC=C)O)O	Ki ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BH63QB	1-[3-[[(2R,3S,4R,5R)-5-[6-(Benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea	Investigative	70676142	C34H46N8O4	630.8	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)NCC5=CC=CC=C5)O)O	Ki ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BIX2R1	Chembl4282866	Investigative	10451940	C19H20N2O2S2	372.5	CCN(CC)S(=O)(=O)C1=CC=C(C=C1)/C=C/C2=NC3=CC=CC=C3S2	IC50 ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BJ6XG7	3-Hydroxy-4-(naphthalen-1-yldiazenyl)-7-nitronaphthalene-1-sulfonic acid	Investigative	135967904	C20H13N3O6S	423.4	C1=CC=C2C(=C1)C=CC=C2N=NC3=C4C=CC(=CC4=C(C=C3O)S(=O)(=O)O)[N+](=O)[O-]	IC50 = 96000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BJM1F7	1-[3-[[(1R,2R,3S,4R)-4-(6-Aminopurin-9-yl)-2,3-dihydroxycyclopentyl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea	Investigative	76328022	C28H42N8O3	538.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@H]2C[C@H]([C@@H]([C@@H]2O)O)N3C=NC4=C(N=CN=C43)N	Ki ~ 50000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BK60CR	1-(4-Tert-butylphenyl)-3-[3-[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]oxolan-2-yl]methyl-propan-2-ylamino]propyl]urea	Investigative	70676140	C28H42N8O4	554.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)NC)O)O	Ki ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BLA4S9	N-[(6-Methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide	Investigative	54596764	C31H39N7O2	541.7	CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C)C(C)C	IC50 ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BLI48Y	2-Benzylsulfanyl-2-methylpropan-1-amine	Investigative	423583	C11H17NS	195.33	CC(C)(CN)SCC1=CC=CC=C1	IC50 = 56500 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BLOG15	4-Hydroxy-6-(phenylamino)naphthalene-2-sulfonic acid	Investigative	67062	C16H13NO4S	315.3	C1=CC=C(C=C1)NC2=CC3=C(C=C(C=C3C=C2)S(=O)(=O)O)O	IC50 = 104200 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BM54QI	2-Hydroxy-5-{[4-(4-methoxy-3-methylphenyl)-1,3-thiazol-2-yl]amino}benzoic acid	Investigative	1192043	C18H16N2O4S	356.4	CC1=C(C=CC(=C1)C2=CSC(=N2)NC3=CC(=C(C=C3)O)C(=O)O)OC	IC50 ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BM6B0V	(2E)-1-Butyl-2-[(E)-3-(1-butyl-3,3-dimethylindol-1-ium-2-yl)prop-2-enylidene]-3,3-dimethylindole;iodide	Investigative	16212292	C31H41IN2	568.6	CCCCN\\1C2=CC=CC=C2C(/C1=C\\C=C\\C3=[N+](C4=CC=CC=C4C3(C)C)CCCC)(C)C.[I-]	IC50 = 160800 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BNO96V	(S)-1-(5-((2-Aminopropanamido)methyl)thiophen-3-yl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide	Investigative	25218467	C21H22F3N5O3S	481.5	C[C@@H](C(=O)NCC1=CC(=CS1)N2C(=CC(=N2)C(F)(F)F)C(=O)NCC3=CC=CC=C3OC)N	IC50 ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BNY74G	N-Benzyl-1-[2-(methylamino)ethyl]piperidin-4-amine	Investigative	137661881	C15H25N3	247.38	CNCCN1CCC(CC1)NCC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BOWZ98	1-[3-[[(3R,4S,5R)-3-(6-Aminopurin-9-yl)-4,5-dihydroxycyclopenten-1-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea	Investigative	76328021	C28H40N8O3	536.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2=C[C@H]([C@@H]([C@@H]2O)O)N3C=NC4=C(N=CN=C43)N	Ki ~ 50000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BPT87C	Methyl 2-[[2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]acetyl]amino]benzoate	Investigative	1002773	C18H17N3O4S	371.4	COC1=CC2=C(C=C1)N=C(N2)SCC(=O)NC3=CC=CC=C3C(=O)OC	IC50 ~ 100000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BQ5ZB2	N-(3-(1H-Imidazol-4-yl)propyl)-9H-purin-6-amine	Investigative	44422923	C11H13N7	243.27	C1=C(NC=N1)CCCNC2=NC=NC3=C2NC=N3	IC50 = 54800 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BR9N7D	4-Iodo-N-[4-(2-phenylethylsulfamoyl)phenyl]benzamide	Investigative	56683405	C21H19IN2O3S	506.4	C1=CC=C(C=C1)CCNS(=O)(=O)C2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)I	IC50 = 68100 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BS18AG	Fluorone black	Investigative	70420	C19H12O5	320.3	C1=CC=C(C=C1)C2=C3C=C(C(=O)C=C3OC4=CC(=C(C=C42)O)O)O	IC50 = 126000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BSX9B5	4'-Sulfanilylbenzanilide	Investigative	208621	C19H16N2O3S	352.4	C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)N	IC50 = 65600 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BT01SJ	1-(2,4,6-Trioxo-tetrahydropyrimidin-5(6H)-ylideneamino)-1,3,5-triazinane-2,4,6-trione	Investigative	44420643	C7H4N6O6	268.14	C1(=NN2C(=O)NC(=O)NC2=O)C(=O)NC(=O)NC1=O	IC50 ~ 164000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	BW20ZO	5'-[(3-{[(4-Tert-Butylphenyl)carbamoyl]amino}propyl)(Propan-2-Yl)amino]-5'-Deoxyadenosine	Investigative	56951879	C27H40N8O4	540.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O	Ki ~ 50000 nM	Poor binder
T16808	Protein arginine methyltransferase 1	D02TVQ	GSK343	Investigative	71268957	C31H39N7O2	541.7	CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CC(=NC=C4)N5CCN(CC5)C)C(C)C	IC50 ~ 100000 nM	Poor binder