TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T17036	Lysine-specific demethylase 4E	B0HR8M	2-[1-(1-Butanoylpyrrolidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191473	C16H19N5O3	329.35	CCCC(=O)N1CCC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B0UTG1	4-((Dimethylamino)oxy)-4-oxobutanoic acid	Investigative	71449736	C6H11NO4	161.16	CN(C)OC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B2ODI9	2-[1-[(3S)-1-Benzoylpiperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	101882872	C20H19N5O3	377.4	C1C[C@@H](CN(C1)C(=O)C2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B4PDR6	2-[1-(1-Acetylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191477	C15H17N5O3	315.33	CC(=O)N1CCCC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B5MF0W	2-[1-(2-Phenylethyl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191459	C16H14N4O2	294.31	C1=CC=C(C=C1)CCN2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B5WC8Q	Potassium;2-(1-benzyltriazol-4-yl)pyridine-4-carboxylate	Investigative	122191457	C15H11KN4O2	318.37	C1=CC=C(C=C1)CN2C=C(N=N2)C3=NC=CC(=C3)C(=O)[O-].[K+]	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B6FWZ9	2-[1-[1-(3-Phenylpropanoyl)piperidin-4-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191466	C22H23N5O3	405.4	C1CN(CCC1N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O)C(=O)CCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B6TEQ4	2-[1-(1-Benzoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191480	C20H19N5O3	377.4	C1CC(CN(C1)C(=O)C2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B70ITZ	2-[1-(1-Ethoxycarbonylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191461	C16H19N5O4	345.35	CCOC(=O)N1CCC(CC1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B74FJW	2-[1-(1-Benzoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191470	C18H15N5O3	349.3	C1C(CN1C(=O)C2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 = 50118.72 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B7RPS8	2-[1-[1-(2-Phenylacetyl)pyrrolidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191475	C20H19N5O3	377.4	C1CN(CC1N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O)C(=O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B8MFB0	2-[1-(1-Butanoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191463	C17H21N5O3	343.4	CCCC(=O)N1CCC(CC1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B9PNO0	4-(Isopropylamino)-4-oxobutanoic acid	Investigative	245007	C7H13NO3	159.18	CC(C)NC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	B9UVL8	2-[(2-Furylmethyl)amino]nicotinic acid	Investigative	28330466	C11H10N2O3	218.21	C1=CC(=C(N=C1)NCC2=CC=CO2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BAT6I0	2-[1-(1-Propanoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191468	C14H15N5O3	301.3	CCC(=O)N1CC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BBE53M	Potassium;2-(1-ethyltriazol-4-yl)pyridine-4-carboxylate	Investigative	122191453	C10H9KN4O2	256.3	CCN1C=C(N=N1)C2=NC=CC(=C2)C(=O)[O-].[K+]	IC50 = 79432.82 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BBL71C	(2S)-3-Benzylsulfanyl-2-(oxaloamino)propanoic acid	Investigative	45104128	C12H13NO5S	283.3	C1=CC=C(C=C1)CSC[C@H](C(=O)O)NC(=O)C(=O)O	IC50 = 200000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BDI7W1	2-(1-Benzylpyrazol-4-yl)oxy-3H-pyrido[2,3-d]pyrimidin-4-one	Investigative	136644692	C17H13N5O2	319.32	C1=CC=C(C=C1)CN2C=C(C=N2)OC3=NC4=C(C=CC=N4)C(=O)N3	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BIXF84	(3-Carboxypropanoylamino)-trimethylazanium	Investigative	71453382	C7H15N2O3+	175.21	C[N+](C)(C)NC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BK2VT0	2-[1-[1-(2-Phenylacetyl)piperidin-4-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191465	C21H21N5O3	391.4	C1CN(CCC1N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O)C(=O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BKD2M4	2-[1-[1-(3-Phenylpropanoyl)piperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191482	C22H23N5O3	405.4	C1CC(CN(C1)C(=O)CCC2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BL1D0W	2-[1-[(3R)-1-Benzoylpiperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	101882871	C20H19N5O3	377.4	C1C[C@H](CN(C1)C(=O)C2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BLR79X	2-[1-(1-Propanoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191462	C16H19N5O3	329.35	CCC(=O)N1CCC(CC1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BN86AV	N'1,N'1,N'4,N'4-Tetramethylsuccinohydrazide	Investigative	2238068	C8H18N4O2	202.25	CN(C)NC(=O)CCC(=O)NN(C)C	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BOE1M8	2-[1-(1-Butanoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191469	C15H17N5O3	315.33	CCCC(=O)N1CC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 79432.82 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BOQ2S3	2-[1-[1-(2-Phenylacetyl)azetidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191471	C19H17N5O3	363.4	C1C(CN1C(=O)CC2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BPE68K	2-[1-[1-(2-Phenylacetyl)piperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191481	C21H21N5O3	391.4	C1CC(CN(C1)C(=O)CC2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BQ6XN3	2-[1-[1-(3-Phenylpropanoyl)pyrrolidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191476	C21H21N5O3	391.4	C1CN(CC1N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O)C(=O)CCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BQW5X1	2-[1-(1-Butanoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191479	C17H21N5O3	343.4	CCCC(=O)N1CCCC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BT3E7X	2-[(3-Methylthiophen-2-yl)methylamino]pyridine-3-carboxylic acid	Investigative	112726150	C12H12N2O2S	248.3	CC1=C(SC=C1)CNC2=C(C=CC=N2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BTC9Q4	2-[1-(1-Propanoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191478	C16H19N5O3	329.35	CCC(=O)N1CCCC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BV2PG8	Potassium;2-[1-(3-methylphenyl)triazol-4-yl]pyridine-4-carboxylate	Investigative	122191455	C15H11KN4O2	318.37	CC1=CC(=CC=C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)[O-].[K+]	IC50 = 50118.72 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BV7X1A	(2S)-3-[(2-Methoxyphenyl)methylsulfanyl]-2-(oxaloamino)propanoic acid	Investigative	56663048	C13H15NO6S	313.33	COC1=CC=CC=C1CSC[C@H](C(=O)O)NC(=O)C(=O)O	IC50 = 200000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BVE23M	4-[Dimethylamino(methyl)amino]-4-oxobutanoic acid	Investigative	71451542	C7H14N2O3	174.2	CN(C)N(C)C(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BVUL43	2-[1-(1-Benzoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191464	C20H19N5O3	377.4	C1CN(CCC1N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O)C(=O)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BW3UN6	Tranylcypromine hydrochloride	Investigative	2723716	C9H12ClN	169.65	C1[C@H]([C@@H]1N)C2=CC=CC=C2.Cl	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BWF9L0	Potassium;2-(1-methyltriazol-4-yl)pyridine-4-carboxylate	Investigative	122191451	C9H7KN4O2	242.28	CN1C=C(N=N1)C2=NC=CC(=C2)C(=O)[O-].[K+]	IC50 = 79432.82 nM	Poor binder
T17036	Lysine-specific demethylase 4E	BX63EH	2-[1-(2-Phenoxyethyl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191460	C16H14N4O3	310.31	C1=CC=C(C=C1)OCCN2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	D08IZY	2-(carboxymethylamino)-2-oxoacetic acid	Investigative	3080614	C4H5NO5	147.09	C(C(=O)O)NC(=O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T17036	Lysine-specific demethylase 4E	D0B2WZ	daminozide	Investigative	15331	C6H12N2O3	160.17	CN(C)NC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder