TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T17687 Fibroblast growth factor receptor B19WYH PD158780 Analog 5h Investigative 5328354 C17H19BrN6 387.3 CN(C)CCNC1=NC=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor B1KOX8 PD158780 Analog 5k Investigative 5328357 C20H25BrN6O 445.4 CCN(CC)CC(CNC1=NC=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)O IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor B1U8YE 6-(2,6-Dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one Investigative 44294903 C14H9Cl2N3O 306.1 CN1C2=NC=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor B7J1GF 7-((4-Methylpiperazin-1-yl)methyl)-3-(thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole Investigative 44414347 C20H22N4S 350.5 CN1CCN(CC1)CC2=CC3=C(CC4=C3NN=C4C5=CSC=C5)C=C2 IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor B86RXE N-[4-[(3-Chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-5-(4-methyl-1-piperazinyl)-2-pentynamide Investigative 11518389 C23H23ClFN7O 467.9 CN1CCN(CC1)CCC#CC(=O)NC2=NC=C3C(=C2)C(=NC=N3)NC4=CC(=C(C=C4)F)Cl IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor BA62KJ N-(3-Bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-amine Investigative 2428 C15H10BrN5 340.18 C1=CC(=CC(=C1)Br)NC2=NC=NC3=CC4=C(C=C32)NC=N4 IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor BEID83 6-(2,6-Dichlorophenyl)-2-(dimethylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one Investigative 5327875 C16H14Cl2N4O 349.2 CN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl)N(C)C IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor BL98OJ 2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 19 Investigative 5327866 C15H11Cl2N3O 320.2 CC1=NC=C2C=C(C(=O)N(C2=N1)C)C3=C(C=CC=C3Cl)Cl IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor BN3Y0E 3-[[5-Cyano-6-(cyclopentylamino)pyrimidin-4-yl]amino]-4-methyl-N-(1,2-oxazol-3-yl)benzamide Investigative 11235063 C21H21N7O2 403.4 CC1=C(C=C(C=C1)C(=O)NC2=NOC=C2)NC3=C(C(=NC=N3)NC4CCCC4)C#N IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor BQTA68 PD158780 Analog 5n Investigative 5328360 C19H21BrN6O 429.3 C1COCCN1CCNC2=NC=C3C(=C2)C(=NC=N3)NC4=CC(=CC=C4)Br IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor BR1F3E Canertinib dihydrochloride Investigative 156413 C24H27Cl3FN5O3 558.9 C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl.Cl IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor BRCV74 PD089828 analog 12 Investigative 5329117 C20H18F6N6O 472.4 CC(C)(C)NC(=O)NC1=C(C=C2C=NC(=NC2=N1)N)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F IC50 ~ 50000 nM Poor binder T17687 Fibroblast growth factor receptor BW3AR5 4-(6,7-Dimethoxy-4-quinazolinyl)-N-(3,4-methylenedioxybenzyl)-1-piperazinethiocarboxamide Investigative 9890746 C23H25N5O4S 467.5 COC1=C(C=C2C(=C1)C(=NC=N2)N3CCN(CC3)C(=S)NCC4=CC5=C(C=C4)OCO5)OC IC50 = 160000 nM Poor binder T17687 Fibroblast growth factor receptor BWYG21 9-Hydroxy-4-phenylpyrrolo[3,4-C]carbazole-1,3(2H,6H)-dione Investigative 4369491 C20H12N2O3 328.3 C1=CC=C(C=C1)C2=CC3=C(C4=C(N3)C=CC(=C4)O)C5=C2C(=O)NC5=O IC50 ~ 50000 nM Poor binder