TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T17758	Urokinase-type plasminogen activator	D0I0RJ	Amiloride	Approved	16231	C6H8ClN7O	229.63	C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N	IC50 = 107000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B09IUL	2-Naphthalenecarboxamide,6-bromo-N-phenyl-	Investigative	57393288	C17H12BrNO	326.2	C1=CC=C(C=C1)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)Br	IC50 ~ 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B0CO7M	N-(5-Phenyl-isoquinolin-1-yl)-guanidine	Investigative	44339192	C16H14N4	262.31	C1=CC=C(C=C1)C2=CC=CC3=C2C=CN=C3N=C(N)N	Ki ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B0KBN8	4-(Aminomethyl)-N-[(2S)-3-[4-(naphthalen-2-ylmethoxy)phenyl]-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide	Investigative	127036847	C36H49N3O3	571.8	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC3=CC=CC=C3C=C2)NC(=O)C4CCC(CC4)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B0L8VD	N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide	Investigative	127045985	C32H33N7O4	579.6	C[C@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)N[C@@H](CCCCN)C#N)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 160000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B0NKA9	4-(Aminomethyl)-N-[(2S)-3-[4-[(3-aminophenyl)methoxy]phenyl]-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide	Investigative	127036644	C32H48N4O3	536.7	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC(=CC=C2)N)NC(=O)C3CCC(CC3)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B0VA5K	2-Aminoquinolin-8-ol	Investigative	4653788	C9H8N2O	160.17	C1=CC2=C(C(=C1)O)N=C(C=C2)N	Ki = 56000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B12FJL	4-[4-(Phenoxymethyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537342	C16H15N3OS3	361.5	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)COC3=CC=CC=C3	Ki = 178000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B14UPZ	1H-Indole-5-carboximidamide	Investigative	122670	C9H9N3	159.19	C1=CC2=C(C=CN2)C=C1C(=N)N	Ki = 131000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B1Y2TO	3-[(R)-3-(4-Methanesulfonyl-piperazin-1-yl)-3-oxo-2-(2,2,5,7,8-pentamethyl-chroman-6-sulfonylamino)-propyl]-benzamidine	Investigative	44335624	C29H41N5O6S2	619.8	CC1=C(C(=C(C2=C1OC(CC2)(C)C)C)S(=O)(=O)N[C@H](CC3=CC(=CC=C3)C(=N)N)C(=O)N4CCN(CC4)S(=O)(=O)C)C	Ki = 58000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B2E8DM	1-(4-Fluorophenyl)guanidine	Investigative	1549311	C7H8FN3	153.16	C1=CC(=CC=C1N=C(N)N)F	Ki = 72400 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B2H8JQ	1-Phenyl-2-(5-carboxybenzoxazole-2-ylthiomethyl)-5-(pivaloyloxy)-1,4-dihydropyridine-4-one	Investigative	72793778	C25H22N2O6S	478.5	CC(C)(C)C(=O)OC1=CN(C(=CC1=O)CSC2=NC3=C(O2)C=CC(=C3)C(=O)O)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B2HX6Q	Methyl (2S)-1-[(2S)-2-[[3-(3-aminopropanoylamino)phenyl]sulfonylamino]-3-(3-carbamimidoylphenyl)propanoyl]piperidine-2-carboxylate	Investigative	44573380	C26H34N6O6S	558.7	COC(=O)[C@@H]1CCCCN1C(=O)[C@H](CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)C3=CC=CC(=C3)NC(=O)CCN	Ki = 126000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B2LFH8	3-[4-[(6-Methoxynaphthalen-2-yl)sulfonylamino]phenyl]benzamide	Investigative	57399538	C24H20N2O4S	432.5	COC1=CC2=C(C=C1)C=C(C=C2)S(=O)(=O)NC3=CC=C(C=C3)C4=CC(=CC=C4)C(=O)N	IC50 ~ 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B2NLP9	4-[4-(4-Chloro-3-pyridinyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537006	C14H11ClN4S3	366.9	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=C(C=CN=C3)Cl	Ki = 164000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B2QD1M	N-[4-(3-Fluorophenyl)phenyl]-6-methoxynaphthalene-2-sulfonamide	Investigative	57399539	C23H18FNO3S	407.5	COC1=CC2=C(C=C1)C=C(C=C2)S(=O)(=O)NC3=CC=C(C=C3)C4=CC(=CC=C4)F	IC50 ~ 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B2R6WK	3-[(R)-3-[4-(2-Hydroxy-ethyl)-piperazin-1-yl]-2-(naphthalene-2-sulfonylamino)-3-oxo-propyl]-benzamidine	Investigative	10815545	C26H31N5O4S	509.6	C1CN(CCN1CCO)C(=O)[C@@H](CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)C3=CC4=CC=CC=C4C=C3	Ki = 140000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B2V1RO	Chembl4126905	Investigative	145960856	C21H26N4O3S	414.5	CC1=CC=C(C=C1)S(=O)(=O)NC(C2CCCC2)C(=O)NC3=CC=C(C=C3)C(=N)N	IC50 = 64000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B3R4VN	N-[4-(3-Aminophenyl)phenyl]-6-methoxynaphthalene-2-sulfonamide	Investigative	57403048	C23H20N2O3S	404.5	COC1=CC2=C(C=C1)C=C(C=C2)S(=O)(=O)NC3=CC=C(C=C3)C4=CC(=CC=C4)N	IC50 = 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B3SQ6U	4-(Aminomethyl)-N-[(2S)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide	Investigative	127035809	C29H49N3O3	487.7	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OC(C)(C)C)NC(=O)C2CCC(CC2)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B3Y0XA	2-[4-[2-[(2-Ethylimidazo[1,2-a]pyridin-3-yl)amino]ethyl]phenyl]guanidine	Investigative	127039699	C18H22N6	322.4	CCC1=C(N2C=CC=CC2=N1)NCCC3=CC=C(C=C3)N=C(N)N	IC50 = 150000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B43NBS	4-[4-(2-Chloro-4-pyridinyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537117	C14H11ClN4S3	366.9	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC(=NC=C3)Cl	Ki = 120000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B45APO	4-[4-(2-Naphthyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537298	C19H15N3S3	381.5	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC4=CC=CC=C4C=C3	Ki = 138000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B4D1IW	(2S)-1-[(2S)-2-[[3-(3-Aminopropanoylamino)phenyl]sulfonylamino]-3-(3-carbamimidoylphenyl)propanoyl]piperidine-2-carboxylic acid	Investigative	44573428	C25H32N6O6S	544.6	C1CCN([C@@H](C1)C(=O)O)C(=O)[C@H](CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)C3=CC=CC(=C3)NC(=O)CCN	Ki = 193000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B4FW2D	[1-(3-Carbamimidoyl-benzyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester	Investigative	4713404	C21H32N4O3	388.5	CC1CCN(CC1)C(=O)C(CC2=CC(=CC=C2)C(=N)N)NC(=O)OC(C)(C)C	Ki = 56000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B4IZ1Y	4-(4-Benzo[b]thiophen-3-yl-thiazol-2-yl)-5-methylsulfanyl-thiophene-2-carboxamidine	Investigative	44278581	C17H13N3S4	387.6	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CSC4=CC=CC=C43	Ki = 141000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B4K5PV	6-Methoxy-N-phenylnaphthalene-2-carboxamide	Investigative	28082833	C18H15NO2	277.3	COC1=CC2=C(C=C1)C=C(C=C2)C(=O)NC3=CC=CC=C3	IC50 ~ 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B4N2CO	Ethyl 3-[[4-[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-(octylamino)-3-oxopropyl]phenoxy]methyl]benzoate	Investigative	127035843	C35H51N3O5	593.8	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC(=CC=C2)C(=O)OCC)NC(=O)C3CCC(CC3)CN	IC50 ~ 50000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B4PEL0	1-[3-(3-Carbamimidoyl-phenyl)-2-(2,4,6-triisopropyl-benzenesulfonylamino)-propionyl]-piperidine-4-carboxylic acid	Investigative	44337001	C31H44N4O5S	584.8	CC(C)C1=CC(=C(C(=C1)C(C)C)S(=O)(=O)NC(CC2=CC(=CC=C2)C(=N)N)C(=O)N3CCC(CC3)C(=O)O)C(C)C	Ki = 52000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B53WTM	4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-[[3-(pyridin-4-ylmethoxy)phenyl]methoxy]phenyl]propan-2-yl]cyclohexane-1-carboxamide	Investigative	127035151	C38H52N4O4	628.8	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC(=CC=C2)OCC3=CC=NC=C3)NC(=O)C4CCC(CC4)CN	IC50 ~ 50000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B54PRQ	Benzyl 2-[[6-amino-3-chloro-5-[(Z)-N'-hydroxycarbamimidoyl]pyrazin-2-yl]amino]acetate	Investigative	136266885	C14H15ClN6O3	350.76	C1=CC=C(C=C1)COC(=O)CNC2=NC(=C(N=C2Cl)/C(=N/O)/N)N	IC50 = 74000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B5F9LD	Benzyl 2-[(6-amino-5-carbamoyl-3-chloropyrazin-2-yl)amino]acetate	Investigative	70689516	C14H14ClN5O3	335.74	C1=CC=C(C=C1)COC(=O)CNC2=NC(=C(N=C2Cl)C(=O)N)N	IC50 = 69000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B5JE7T	N-(4-Guanidino-phenyl)-2-hydroxy-3-methyl-benzamide	Investigative	44304353	C15H16N4O2	284.31	CC1=C(C(=CC=C1)C(=O)NC2=CC=C(C=C2)N=C(N)N)O	Ki = 60000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B5MTX3	Nalpha-[trans-4-(Aminomethyl)cyclohexane-1-Carbonyl]-N-Octyl-O-[(Quinolin-2-Yl)methyl]-L-Tyrosinamide	Investigative	127021019	C35H48N4O3	572.8	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=NC3=CC=CC=C3C=C2)NC(=O)C4CCC(CC4)CN	IC50 = 77000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B5S3JN	(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-Amino-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-11-(carboxymethyl)-23-(hydroxymethyl)-17,26-bis[(4-hydroxyphenyl)methyl]-29-methyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid	Investigative	127037469	C54H77N13O16S2	1228.4	C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N1)N)C(=O)O)CC(=O)O)CC(C)C)CC3=CC=C(C=C3)O)CC4CCN(CC4)C(=N)N)CO)CC5=CC=C(C=C5)O	Ki = 93000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B5YJU9	4-[4-(3-Nitro-4-chlorophenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537287	C15H11ClN4O2S3	410.9	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]	Ki = 161000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B61RCQ	[4-[3-(Diaminomethylideneamino)propyl]-3,6,9-trioxo-2,5,8-triazabicyclo[8.3.1]tetradeca-1(14),10,12-trien-11-yl]methyl-methyl-phenylsulfanium;bromide	Investigative	45266266	C23H29BrN6O3S	549.5	C[S+](CC1=C2C=C(C=C1)NC(=O)C(NC(=O)CNC2=O)CCCN=C(N)N)C3=CC=CC=C3.[Br-]	Ki = 90000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B63RZJ	US8569313, Inhibitor 35	Investigative	44569359	C30H38N4O4S	550.7	COC1=CC=C(C=C1)C2=CC(=CC=C2)S(=O)(=O)NC(CC3=CC(=CC=C3)CN)C(=O)N4CCC(CC4)CCN	Ki = 129000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B6ENJ9	Chembl4128355	Investigative	145960913	C22H22N4O3S	422.5	CC1=CC=C(C=C1)S(=O)(=O)NC(C2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)C(=N)N	IC50 = 60000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B6J4HU	3-Amino-N-(diaminomethylidene)-5-(2-phenylethylamino)pyrazine-2-carboxamide;hydrochloride	Investigative	57394515	C14H18ClN7O	335.79	C1=CC=C(C=C1)CCNC2=CN=C(C(=N2)N)C(=O)N=C(N)N.Cl	IC50 = 120000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B6SHC7	(R)-N-[(5-Chloro-2-ethyl-benzylcarbamoyl)-methyl]-4-(1-oxy-pyridin-2-yl)-2-phenylmethanesulfonylamino-butyramide	Investigative	44426219	C26H30ClN5O5S	560.1	C1=CC=C(C=C1)CS(=O)(=O)N[C@H](CCC2=CC=CC=[N+]2[O-])C(=O)NCC(=O)NCC3=C(C=CC(=C3)Cl)CN	Ki = 150000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B6WB1G	1-Methyl-1h-indole-5-carboximidamide	Investigative	18545754	C10H11N3	173.21	CN1C=CC2=C1C=CC(=C2)C(=N)N	Ki = 196000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B70AVX	4-Tert-Butoxycarbonylamino-4-{[(4-carbamimidoyl-benzylcarbamoyl)-methyl]-carbamoyl}-butyric acid	Investigative	44372724	C20H29N5O6	435.5	CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)NCC(=O)NCC1=CC=C(C=C1)C(=N)N	Ki = 82000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B7E4IQ	Methyl 6-(phenylcarbamoyl)naphthalene-2-carboxylate	Investigative	57400206	C19H15NO3	305.3	COC(=O)C1=CC2=C(C=C1)C=C(C=C2)C(=O)NC3=CC=CC=C3	IC50 ~ 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B80IOT	3-[[12-(Azepan-1-yl)-8-oxo-15-oxa-14-azatetracyclo[7.6.1.02,7.013,16]hexadeca-1(16),2,4,6,9,11,13-heptaen-10-yl]amino]benzoic acid	Investigative	3675673	C27H23N3O4	453.5	C1CCCN(CC1)C2=CC(=C3C4=C(C5=CC=CC=C5C3=O)ON=C24)NC6=CC=CC(=C6)C(=O)O	IC50 = 50000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B82ALP	4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537190	C17H15N3O2S3	389.5	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC4=C(C=C3)OCCO4	Ki = 108000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B87OAE	Diphenyl N-(benzyloxycarbonyl)amino(4-amidinophenyl)methanephosphonate	Investigative	9827867	C28H26N3O5P	515.5	C1=CC=C(C=C1)COC(=O)NC(C2=CC=C(C=C2)C(=N)N)P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4	IC50 = 60000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B8MF4U	3-Hydroxy-N-{[4-(N-hydroxycarbamimidoyl)-benzylcarbamoyl]-methyl}-2-phenylmethanesulfonylamino-propionamide	Investigative	44372840	C20H25N5O6S	463.5	C1=CC=C(C=C1)CS(=O)(=O)N[C@H](CO)C(=O)NCC(=O)NCC2=CC=C(C=C2)/C(=N/O)/N	Ki = 61000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B8RO5E	4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-[[2-(trifluoromethyl)phenyl]methoxy]phenyl]propan-2-yl]cyclohexane-1-carboxamide	Investigative	127036645	C33H46F3N3O3	589.7	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=CC=C2C(F)(F)F)NC(=O)C3CCC(CC3)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B96CHF	4-[4-(2-Methoxyphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537198	C16H15N3OS3	361.5	COC1=CC=CC=C1C2=CSC(=N2)C3=C(SC(=C3)C(=N)N)SC	Ki = 130000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B9OBX0	2-Phenyl-1H-benzimidazole-5-carboxamidine	Investigative	11009950	C14H12N4	236.27	C1=CC=C(C=C1)C2=NC3=C(N2)C=C(C=C3)C(=N)N	Ki = 55000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B9QO4W	2-(3-Methoxy-2-pyridinyl)guanidine	Investigative	44297867	C7H10N4O	166.18	COC1=C(N=CC=C1)N=C(N)N	Ki = 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	B9QT5V	2-[4-[[[2-(4-Fluorophenyl)imidazo[1,2-a]pyridin-3-yl]amino]methyl]phenyl]guanidine	Investigative	127041161	C21H19FN6	374.4	C1=CC2=NC(=C(N2C=C1)NCC3=CC=C(C=C3)N=C(N)N)C4=CC=C(C=C4)F	IC50 = 125000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BA67KJ	3-Amino-6-chloro-N-(diaminomethylidene)-5-[2-(2H-tetrazol-5-yl)ethylamino]pyrazine-2-carboxamide;hydrochloride	Investigative	57392706	C9H13Cl2N11O	362.18	C(CNC1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N)C2=NNN=N2.Cl	IC50 = 61000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BAF07G	UCD74A HCl	Investigative	57392795	C8H11Cl2N7O3	324.12	C(C(=O)O)NC1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N.Cl	IC50 = 110000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BAUK64	(S)-Ethyl 1-(5-(4-phenethoxybenzyl)-1,2,4-oxadiazol-3-yl)-6-amino-1-oxohexan-2-ylcarbamate	Investigative	15984063	C26H32N4O5	480.6	CCOC(=O)N[C@@H](CCCCN)C(=O)C1=NOC(=N1)CC2=CC=C(C=C2)OCCC3=CC=CC=C3	Ki ~ 150000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BB07ES	N-(2-Methoxy-phenyl)-guanidine	Investigative	12336481	C8H11N3O	165.19	COC1=CC=CC=C1N=C(N)N	Ki = 136000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BB0MR4	8-Furan-3-yl-7-methoxy-naphthalene-2-carboxamidine	Investigative	21707001	C16H14N2O2	266.29	COC1=C(C2=C(C=CC(=C2)C(=N)N)C=C1)C3=COC=C3	Ki = 82000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BB7C6R	(S)-1-(9-Hydroxy-9H-3-aza-fluorene-9-carbonyl)-pyrrolidine-2-carboxylic acid 2-aminomethyl-5-chloro-benzylamide	Investigative	11317532	C26H25ClN4O3	477	C1C[C@H](N(C1)C(=O)C2(C3=C(C=NC=C3)C4=CC=CC=C42)O)C(=O)NCC5=C(C=CC(=C5)Cl)CN	Ki ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BBW5P4	4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-(quinolin-8-ylmethoxy)phenyl]propan-2-yl]cyclohexane-1-carboxamide	Investigative	127036848	C35H48N4O3	572.8	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=CC3=C2N=CC=C3)NC(=O)C4CCC(CC4)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BC86XE	4-(Aminomethyl)-N-[(2S)-3-[4-(naphthalen-1-ylmethoxy)phenyl]-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide	Investigative	127036012	C36H49N3O3	571.8	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=CC3=CC=CC=C32)NC(=O)C4CCC(CC4)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BCE1G5	5-Methylsulfanyl-4-(4-p-tolyl-thiazol-2-yl)-thiophene-2-carboxamidine	Investigative	18536880	C16H15N3S3	345.5	CC1=CC=C(C=C1)C2=CSC(=N2)C3=C(SC(=C3)C(=N)N)SC	Ki = 94000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BCJ24N	N-[4-(3-Chlorophenyl)phenyl]-6-methoxynaphthalene-2-sulfonamide	Investigative	57396080	C23H18ClNO3S	423.9	COC1=CC2=C(C=C1)C=C(C=C2)S(=O)(=O)NC3=CC=C(C=C3)C4=CC(=CC=C4)Cl	IC50 ~ 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BCOL14	4-[4-(2-Chloro-3-pyridinyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537047	C14H11ClN4S3	366.9	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=C(N=CC=C3)Cl	Ki = 154000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BCW1U3	2-Aminobenzimidazole	Investigative	13624	C7H7N3	133.15	C1=CC=C2C(=C1)NC(=N2)N	IC50 = 200000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BD5E2V	(2-Nitro-phenyl)-guanidine	Investigative	3580940	C7H8N4O2	180.16	C1=CC=C(C(=C1)N=C(N)N)[N+](=O)[O-]	Ki = 54300 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BE1HI9	2-(6-Methyl-2-pyridinyl)guanidine	Investigative	44297837	C7H10N4	150.18	CC1=NC(=CC=C1)N=C(N)N	Ki = 173000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BE4T9P	Chembl4127304	Investigative	145962360	C23H30N4O3S	442.6	CC1=CC=C(C=C1)S(=O)(=O)NC(CC(=O)NC2=CC=C(C=C2)C(=N)N)C3CCCCC3	IC50 = 68000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BF81LX	4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-(4-phenylmethoxyphenyl)propan-2-yl]cyclohexane-1-carboxamide	Investigative	127035810	C32H47N3O3	521.7	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=CC=C2)NC(=O)C3CCC(CC3)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BF9E1H	2-[4-[[[2-Pyridin-3-yl-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]amino]methyl]phenyl]guanidine	Investigative	127041468	C21H18F3N7	425.4	C1=CC(=CN=C1)C2=C(N3C=C(C=CC3=N2)C(F)(F)F)NCC4=CC=C(C=C4)N=C(N)N	IC50 = 200000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BG5A6N	2-[4-[[[2-(3,5-Dichlorophenyl)imidazo[1,2-a]pyridin-3-yl]amino]methyl]phenyl]guanidine	Investigative	127040837	C21H18Cl2N6	425.3	C1=CC2=NC(=C(N2C=C1)NCC3=CC=C(C=C3)N=C(N)N)C4=CC(=CC(=C4)Cl)Cl	IC50 = 99160 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BG7PE2	2-[[[[(4-Methylphenyl)sulfonyl]amino]acetyl]amino]-3-[3-(diaminomethyl)phenyl]propanoic acid methyl ester	Investigative	44367430	C20H26N4O5S	434.5	CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)NC(CC2=CC(=CC=C2)C(N)N)C(=O)OC	Ki = 78000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BH6VG8	N-Phenylnaphthalene-2-carboxamide	Investigative	7038665	C17H13NO	247.29	C1=CC=C(C=C1)NC(=O)C2=CC3=CC=CC=C3C=C2	IC50 ~ 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BH8B0C	4-[4-(2-Thienyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18536775	C13H11N3S4	337.5	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC=CS3	Ki = 89000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BHLG83	4-(Aminomethyl)-N-[(2S)-3-[4-[(3-nitrophenyl)methoxy]phenyl]-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide	Investigative	127036643	C32H46N4O5	566.7	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC(=CC=C2)[N+](=O)[O-])NC(=O)C3CCC(CC3)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BI97QF	Chembl2332610	Investigative	71716976	C64H93N17O16S3	1452.7	C[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CSCC2=CC3=CC(=C2)CSC[C@@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N4CCC[C@H]4C(=O)N[C@@H](CSC3)C(=O)N5CCC[C@H]5C(=O)N6CCC[C@H]6C(=O)N1)CCCN=C(N)N)NC(=O)[C@H](CO)N)C(=O)N[C@@H](CCCCN)C(=O)O)CC7=CC=C(C=C7)O	Ki ~ 120000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BIL7W2	N-(2-Chloro-phenyl)-guanidine	Investigative	12253678	C7H8ClN3	169.61	C1=CC=C(C(=C1)N=C(N)N)Cl	Ki = 103000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BIR2K1	3-[(R)-3-(4-Methyl-piperazin-1-yl)-2-(naphthalene-2-sulfonylamino)-3-oxo-propyl]-benzamidine	Investigative	10648370	C25H29N5O3S	479.6	CN1CCN(CC1)C(=O)[C@@H](CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)C3=CC4=CC=CC=C4C=C3	Ki = 110000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BJ40SQ	4-[4-(3,4-Dihydro-2H-1,5-benzodioxepin-7-yl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	44278529	C18H17N3O2S3	403.5	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC4=C(C=C3)OCCCO4	Ki = 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BJ7VD0	2-(4-Methyl-2-pyridinyl)guanidine	Investigative	44297819	C7H10N4	150.18	CC1=CC(=NC=C1)N=C(N)N	Ki = 83800 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BJ98LI	N-[(2S)-6-Amino-1-[5-[[4-[2-(3,4-dichlorophenyl)ethoxy]phenyl]methyl]-1,2,4-oxadiazol-3-yl]-1-oxohexan-2-yl]-3,4-difluorobenzamide;hydrochloride	Investigative	45263389	C30H29Cl3F2N4O4	653.9	C1=CC(=CC=C1CC2=NC(=NO2)C(=O)[C@H](CCCCN)NC(=O)C3=CC(=C(C=C3)F)F)OCCC4=CC(=C(C=C4)Cl)Cl.Cl	Ki ~ 150000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BK52NL	6-(Phenylcarbamoyl)naphthalene-2-carboxylic acid	Investigative	57390877	C18H13NO3	291.3	C1=CC=C(C=C1)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O	IC50 ~ 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BKCY57	1H-Indole-6-carboximidamide, 3-(2,2,2-trifluoroacetyl)-	Investigative	44331988	C11H8F3N3O	255.2	C1=CC2=C(C=C1C(=N)N)NC=C2C(=O)C(F)(F)F	Ki ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BKR8B7	3-Amidinophenylalanine deriv., 28	Investigative	11570759	C30H38N8O4S	606.7	C1CN(CCN1C(=O)CCN=C(N)N)C(=O)[C@H](CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)CCC3=CC=CC4=CC=CC=C43	Ki = 56000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BKY1W5	4-[4-(4-Chlorophenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	9929077	C15H12ClN3S3	365.9	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC=C(C=C3)Cl	Ki = 99000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BL05NK	4-[4-(1,3-Benzodioxole-5-yl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	10248900	C16H13N3O2S3	375.5	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC4=C(C=C3)OCO4	Ki = 91000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BL1K2D	2-[4-[2-[[2-(3-Chlorophenyl)imidazo[1,2-a]pyrazin-3-yl]amino]ethyl]phenyl]guanidine	Investigative	127041162	C21H20ClN7	405.9	C1=CC(=CC(=C1)Cl)C2=C(N3C=CN=CC3=N2)NCCC4=CC=C(C=C4)N=C(N)N	IC50 = 53780 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BL4F1V	2-[4-[[(6-Fluoro-2-pyridin-3-ylimidazo[1,2-a]pyridin-3-yl)amino]methyl]phenyl]guanidine	Investigative	127041469	C20H18FN7	375.4	C1=CC(=CN=C1)C2=C(N3C=C(C=CC3=N2)F)NCC4=CC=C(C=C4)N=C(N)N	IC50 = 57550 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BL5BC6	4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]propan-2-yl]cyclohexane-1-carboxamide	Investigative	127035840	C33H46F3N3O3	589.7	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC(=CC=C2)C(F)(F)F)NC(=O)C3CCC(CC3)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BLE4Q6	(5-Chloro-2-guanidino-pyridin-3-yloxy)-acetic acid	Investigative	44298458	C8H9ClN4O3	244.63	C1=C(C=NC(=C1OCC(=O)O)N=C(N)N)Cl	Ki = 90200 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BLQ95X	3-[[6-Amino-3-chloro-5-(diaminomethylidenecarbamoyl)pyrazin-2-yl]amino]propanoic acid;hydrochloride	Investigative	57396266	C9H13Cl2N7O3	338.15	C(CNC1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N)C(=O)O.Cl	IC50 = 102000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BLZX12	2-(Benzothiazole-2-ylthiomethyl)-5-(pivaloyloxy)-4H-pyran-4-one	Investigative	72793747	C18H17NO4S2	375.5	CC(C)(C)C(=O)OC1=COC(=CC1=O)CSC2=NC3=CC=CC=C3S2	IC50 ~ 50000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BM0XI7	2-(5-Carboxybenzoxazole-2-ylthiomethyl)-5-(pivaloyloxy)-4H-pyran-4-one	Investigative	72793776	C19H17NO7S	403.4	CC(C)(C)C(=O)OC1=COC(=CC1=O)CSC2=NC3=C(O2)C=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BM4V5Y	Chembl4126725	Investigative	145960395	C19H23BrN2O3S	439.4	CCCCC(C(=O)NC1=CC=C(C=C1)Br)NS(=O)(=O)C2=CC=C(C=C2)C	IC50 = 58000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BM6ND8	Chembl2332604	Investigative	71716975	C59H82N16O15S3	1351.6	C[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CSCC2=CC3=CC(=C2)CSC[C@@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N4CCC[C@H]4C(=O)N[C@@H](CSC3)C(=O)N5CCC[C@H]5C(=O)N6CCC[C@H]6C(=O)N1)CCCN=C(N)N)NC(=O)CN)C(=O)NCC(=O)O)CC7=CC=C(C=C7)O	Ki ~ 120000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BM6PX2	4-(Aminomethyl)-N-[(2S)-3-(4-hydroxyphenyl)-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide	Investigative	127037562	C25H41N3O3	431.6	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C2CCC(CC2)CN	IC50 = 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BM8R3S	N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-3-methylbutyl]-3-methylbenzimidazole-5-carboxamide	Investigative	127046792	C35H39N7O4	621.7	CC(C)C[C@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)N[C@@H](CCCCN)C#N)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 150000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BN37PT	Quinoline-2,6-diamine	Investigative	22018948	C9H9N3	159.19	C1=CC2=C(C=CC(=N2)N)C=C1N	Ki = 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BN6MG1	4-[4-(3-Hydroxyphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	10472893	C15H13N3OS3	347.5	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC(=CC=C3)O	Ki = 86000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BNF7Y6	2-[4-[[[2-(4-Ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]methyl]phenyl]guanidine	Investigative	127040833	C23H24N6	384.5	CCC1=CC=C(C=C1)C2=C(N3C=CC=CC3=N2)NCC4=CC=C(C=C4)N=C(N)N	IC50 = 63920 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BNPV54	3-[3-(4-Methyl-piperazin-1-yl)-3-oxo-2-(2,4,6-triisopropyl-benzenesulfonylamino)-propyl]-benzamidine	Investigative	44336995	C30H45N5O3S	555.8	CC(C)C1=CC(=C(C(=C1)C(C)C)S(=O)(=O)NC(CC2=CC(=CC=C2)C(=N)N)C(=O)N3CCN(CC3)C)C(C)C	Ki = 52000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BO0W9Y	4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-[(3-phenylphenyl)methoxy]phenyl]propan-2-yl]cyclohexane-1-carboxamide	Investigative	127025119	C38H51N3O3	597.8	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=CC=C3)NC(=O)C4CCC(CC4)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BOAL61	1-(3-Chlorophenyl)guanidine	Investigative	10374840	C7H8ClN3	169.61	C1=CC(=CC(=C1)Cl)N=C(N)N	Ki = 61659.5 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BOP61V	N-(4-Ethylphenyl)guanidine	Investigative	3631189	C9H13N3	163.22	CCC1=CC=C(C=C1)N=C(N)N	Ki = 90700 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BOUZ73	2-(3-Phenyl-5-chloro-2-pyridinyl)guanidine	Investigative	44298526	C12H11ClN4	246.69	C1=CC=C(C=C1)C2=C(N=CC(=C2)Cl)N=C(N)N	Ki = 166300 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BQ4GE2	Guanidine, N-(4-methoxy-2-pyridinyl)-	Investigative	44297835	C7H10N4O	166.18	COC1=CC(=NC=C1)N=C(N)N	Ki = 53300 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BR1ZG9	2-Hydroxy-biphenyl-3-carboxylic acid (4-guanidino-phenyl)-amide	Investigative	44304105	C20H18N4O2	346.4	C1=CC=C(C=C1)C2=C(C(=CC=C2)C(=O)NC3=CC=C(C=C3)N=C(N)N)O	Ki ~ 75000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BR56DV	N-[1-(3-Diaminomethyl-benzyl)-2-oxo-2-piperidin-1-yl-ethyl]-4-methyl-benzenesulfonamide	Investigative	44367444	C22H30N4O3S	430.6	CC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CC(=CC=C2)C(N)N)C(=O)N3CCCCC3	Ki = 55000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BR5L2F	4-[4-(2,4-Dimethoxyphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537468	C17H17N3O2S3	391.5	COC1=CC(=C(C=C1)C2=CSC(=N2)C3=C(SC(=C3)C(=N)N)SC)OC	Ki = 152000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BRI4B7	3-Amino-6-chloro-5-(cyanomethylamino)-N-(diaminomethylidene)pyrazine-2-carboxamide;hydrochloride	Investigative	57397994	C8H10Cl2N8O	305.12	C(C#N)NC1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N.Cl	IC50 = 50000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BS24WO	3-[3-Morpholin-4-yl-2-(naphthalene-2-sulfonylamino)-3-oxo-propyl]-benzamidine	Investigative	4713353	C24H26N4O4S	466.6	C1COCCN1C(=O)C(CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)C3=CC4=CC=CC=C4C=C3	Ki = 58000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BS90DU	Chembl4129836	Investigative	145960760	C22H22N4O3S	422.5	CC1=CC=C(C=C1)S(=O)(=O)N[C@H](C2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)C(=N)N	IC50 = 140000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BSD78V	2-(3-Hydroxy-2-pyridinyl)guanidine	Investigative	44297834	C6H8N4O	152.15	C1=CC(=C(N=C1)N=C(N)N)O	Ki = 147000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BSW06M	3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-pyrrolidin-1-yl-propyl]-benzamidine	Investigative	4713323	C24H26N4O3S	450.6	C1CCN(C1)C(=O)C(CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)C3=CC4=CC=CC=C4C=C3	Ki = 73000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BTKF70	2-[4-(Imidazo[1,2-a]pyridin-3-ylamino)butyl]guanidine	Investigative	127041381	C12H18N6	246.31	C1=CC2=NC=C(N2C=C1)NCCCCN=C(N)N	IC50 = 200000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BU3N5E	4-[[4-[(2S)-2-[[4-(Aminomethyl)cyclohexanecarbonyl]amino]-3-(octylamino)-3-oxopropyl]phenoxy]methyl]benzoic acid	Investigative	127036011	C33H47N3O5	565.7	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=C(C=C2)C(=O)O)NC(=O)C3CCC(CC3)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BUD87Q	Methyl (2R)-1-[(2S)-2-[[3-(3-aminopropanoylamino)phenyl]sulfonylamino]-3-(3-carbamimidoylphenyl)propanoyl]piperidine-2-carboxylate	Investigative	44573379	C26H34N6O6S	558.7	COC(=O)[C@H]1CCCCN1C(=O)[C@H](CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)C3=CC=CC(=C3)NC(=O)CCN	Ki = 76000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BUW65F	6-Cyano-N-phenylnaphthalene-2-carboxamide	Investigative	11254287	C18H12N2O	272.3	C1=CC=C(C=C1)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)C#N	IC50 ~ 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BV4FC0	N-Butyl-3-[[4-(diaminomethylideneamino)phenyl]methylamino]-2-pyridin-3-ylimidazo[1,2-a]pyridine-6-carboxamide	Investigative	127041470	C25H28N8O	456.5	CCCCNC(=O)C1=CN2C(=NC(=C2NCC3=CC=C(C=C3)N=C(N)N)C4=CN=CC=C4)C=C1	IC50 = 60840 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BVF27P	4-[4-(3-Methoxyphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	9822176	C16H15N3OS3	361.5	COC1=CC=CC(=C1)C2=CSC(=N2)C3=C(SC(=C3)C(=N)N)SC	Ki = 115000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BVK6B1	4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]propan-2-yl]cyclohexane-1-carboxamide	Investigative	127035841	C33H46F3N3O3	589.7	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=C(C=C2)C(F)(F)F)NC(=O)C3CCC(CC3)CN	IC50 ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BW25QT	4-[4-[4-(Mesylamino)phenyl]-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537001	C16H16N4O2S4	424.6	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC=C(C=C3)NS(=O)(=O)C	Ki = 94000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BW68IR	3-Amino-6-chloro-N-(diaminomethylidene)-5-(2H-tetrazol-5-ylmethylamino)pyrazine-2-carboxamide;hydrochloride	Investigative	57401402	C8H11Cl2N11O	348.15	C(C1=NNN=N1)NC2=NC(=C(N=C2Cl)C(=O)N=C(N)N)N.Cl	IC50 = 177000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BW95UA	N-[3-(11-Bromomethyl-3,6,9-trioxo-2,5,8-triaza-bicyclo[8.3.1]tetradeca-1(13),10(14),11-trien-4-yl)-propyl]-guanidine	Investigative	44285724	C16H21BrN6O3	425.28	C1C(=O)NC(C(=O)NC2=CC(=C(C=C2)CBr)C(=O)N1)CCCN=C(N)N	Ki = 92000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BY4NC2	4-[4-(5,6,7,8-Tetrahydronaphthalene-2-yl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	44278565	C19H19N3S3	385.6	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC4=C(CCCC4)C=C3	Ki = 145000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BY7Z4D	1H-Indole-6-carboximidamide, 3-acetyl-	Investigative	44331989	C11H11N3O	201.22	CC(=O)C1=CNC2=C1C=CC(=C2)C(=N)N	Ki ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BY9HA0	3,4-Dihydroquinazoline	Investigative	583065	C8H8N2	132.16	C1C2=CC=CC=C2NC=N1	Ki = 50118.72 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BYA8T6	2-[4-[[[2-(3-Fluorophenyl)imidazo[1,2-a]pyridin-3-yl]amino]methyl]phenyl]guanidine	Investigative	127041160	C21H19FN6	374.4	C1=CC2=NC(=C(N2C=C1)NCC3=CC=C(C=C3)N=C(N)N)C4=CC(=CC=C4)F	IC50 = 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BYJ5K3	6-Amino-N-phenylnaphthalene-2-carboxamide	Investigative	57402007	C17H14N2O	262.3	C1=CC=C(C=C1)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)N	IC50 ~ 62000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BYQT65	6-Amino-1-naphthol	Investigative	90295	C10H9NO	159.18	C1=CC2=C(C=CC(=C2)N)C(=C1)O	Ki = 50118.72 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BZ4N7V	1-Aminoisoquinoline	Investigative	73742	C9H8N2	144.17	C1=CC=C2C(=C1)C=CN=C2N	Ki = 50118.72 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BZ86CF	3-[[4-[(2S)-2-[[4-(Aminomethyl)cyclohexanecarbonyl]amino]-3-(octylamino)-3-oxopropyl]phenoxy]methyl]benzoic acid	Investigative	127035844	C33H47N3O5	565.7	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC(=CC=C2)C(=O)O)NC(=O)C3CCC(CC3)CN	IC50 ~ 50000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	BZSH38	N-(4-Guanidino-phenyl)-2-hydroxy-5-nitro-benzamide	Investigative	44303721	C14H13N5O4	315.28	C1=CC(=CC=C1NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])O)N=C(N)N	Ki ~ 75000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	D02NRY	(4-bromo-1H-pyrazol-1-yl)(o-tolyl)methanone	Investigative	674650	C11H9BrN2O	265.11	CC1=CC=CC=C1C(=O)N2C=C(C=N2)Br	IC50 = 51200 nM	Poor binder
T17758	Urokinase-type plasminogen activator	D0EH1F	1-(3-Nitro-benzyl)-1H-indole-5-carboxamidine	Investigative	44332057	C16H14N4O2	294.31	C1=CC(=CC(=C1)[N+](=O)[O-])CN2C=CC3=C2C=CC(=C3)C(=N)N	Ki ~ 100000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	D0M2PE	1-Benzyl-1H-indole-5-carboxamidine	Investigative	29012033	C16H15N3	249.31	C1=CC=C(C=C1)CN2C=CC3=C2C=CC(=C3)C(=N)N	Ki = 191000 nM	Poor binder
T17758	Urokinase-type plasminogen activator	D0P7NY	PF-429242	Investigative	23661637	C25H35N3O2	409.6	CCN(CC)CC1=CC=C(C=C1)C(=O)N(CCC2=CC=CC=C2OC)[C@@H]3CCNC3	IC50 = 50000 nM	Poor binder