TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T18664	Monoglyceride lipase	B0T3NC	3-[(4S)-1-[2-(5-Fluoro-1H-indol-3-yl)ethyl]-2,5-dioxoimidazolidin-4-yl]-N-[(1S,2S)-2-methylcyclohexyl]propanamide	Investigative	41111610	C23H29FN4O3	428.5	C[C@H]1CCCC[C@@H]1NC(=O)CC[C@H]2C(=O)N(C(=O)N2)CCC3=CNC4=C3C=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T18664	Monoglyceride lipase	B0T7JH	(Z)-N-(2-Hydroxyethyl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide	Investigative	118727546	C25H35NO5	429.5	C1[C@H]([C@@H]([C@H](C1=O)C/C=C\\CCCC(=O)NCCO)/C=C/[C@@H](CCC2=CC=CC=C2)O)O	IC50 ~ 100000 nM	Poor binder
T18664	Monoglyceride lipase	B0TC6O	4-Bromo-N-(2-phenylethyl)benzenecarbothioamide	Investigative	20110407	C15H14BrNS	320.2	C1=CC=C(C=C1)CCNC(=S)C2=CC=C(C=C2)Br	IC50 = 97723.72 nM	Poor binder
T18664	Monoglyceride lipase	B17FUA	[5-(4-Hydroxyphenyl)-1-methylpyrazol-3-yl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	Investigative	137653907	C19H20N6O2	364.4	CN1C(=CC(=N1)C(=O)N2CCN(CC2)C3=NC=CC=N3)C4=CC=C(C=C4)O	IC50 = 132000 nM	Poor binder
T18664	Monoglyceride lipase	B1SH0Y	(4-Methylpiperazine-1-carbothioyl)sulfanylmethyl 4-methylpiperazine-1-carbodithioate	Investigative	44550864	C13H24N4S4	364.6	CN1CCN(CC1)C(=S)SCSC(=S)N2CCN(CC2)C	IC50 = 95499.26 nM	Poor binder
T18664	Monoglyceride lipase	B3LA9W	[(1R)-1-[(2R,3R)-2-Acetyloxy-4-oxo-1-pent-4-enoylazetidin-3-yl]ethyl] pent-4-enoate	Investigative	42631278	C17H23NO6	337.4	C[C@H]([C@@H]1[C@H](N(C1=O)C(=O)CCC=C)OC(=O)C)OC(=O)CCC=C	IC50 = 133000 nM	Poor binder
T18664	Monoglyceride lipase	B3U6QF	(Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]-N-(3-hydroxypropyl)hept-5-enamide	Investigative	118727550	C26H37NO5	443.6	C1[C@H]([C@@H]([C@H](C1=O)C/C=C\\CCCC(=O)NCCCO)/C=C/[C@H](CCC2=CC=CC=C2)O)O	IC50 ~ 100000 nM	Poor binder
T18664	Monoglyceride lipase	B4V7AC	[(1R)-1-[(3S)-2-Oxo-1-(prop-2-enylcarbamoyl)azetidin-3-yl]ethyl] 4-phenylbutanoate	Investigative	71575476	C19H24N2O4	344.4	C[C@H]([C@@H]1CN(C1=O)C(=O)NCC=C)OC(=O)CCCC2=CC=CC=C2	IC50 = 98410 nM	Poor binder
T18664	Monoglyceride lipase	B5RIM4	(Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]-N-[(2S)-1-hydroxypropan-2-yl]hept-5-enamide	Investigative	118727549	C26H37NO5	443.6	C[C@@H](CO)NC(=O)CCC/C=C\\C[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](CCC2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T18664	Monoglyceride lipase	B5U1TO	Psncbam-1	Investigative	11560249	C22H21ClN4O	392.9	C1CCN(C1)C2=CC=CC(=N2)C3=CC(=CC=C3)NC(=O)NC4=CC=C(C=C4)Cl	IC50 ~ 100000 nM	Poor binder
T18664	Monoglyceride lipase	B5WC2P	1-Chloro-3-[4-(2-methylpropyl)phenyl]butan-2-one	Investigative	46933427	C14H19ClO	238.75	CC(C)CC1=CC=C(C=C1)C(C)C(=O)CCl	IC50 = 199526.23 nM	Poor binder
T18664	Monoglyceride lipase	B6Y7OB	(4-Chlorophenyl)-morpholin-4-ylmethanethione	Investigative	684261	C11H12ClNOS	241.74	C1COCCN1C(=S)C2=CC=C(C=C2)Cl	IC50 = 77624.71 nM	Poor binder
T18664	Monoglyceride lipase	B6ZUN2	N-[5-(4-Fluorophenyl)-10-oxo-2,3,7,8,11-pentazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,12-pentaen-11-yl]-2-naphthalen-2-yloxyacetamide	Investigative	45591408	C26H17FN6O3	480.4	C1=CC=C2C=C(C=CC2=C1)OCC(=O)NN3C=CC4=C(C3=O)N=NC5=C(C=NN45)C6=CC=C(C=C6)F	IC50 ~ 100000 nM	Poor binder
T18664	Monoglyceride lipase	B79HSK	2-Chloro-N-(2-phenylethyl)benzenecarbothioamide	Investigative	76323091	C15H14ClNS	275.8	C1=CC=C(C=C1)CCNC(=S)C2=CC=CC=C2Cl	IC50 = 165958.69 nM	Poor binder
T18664	Monoglyceride lipase	B8CN1Q	[(1R)-1-[(3S)-2-Oxo-1-(prop-2-enylcarbamoyl)azetidin-3-yl]ethyl] 2-phenylmethoxyacetate	Investigative	71575575	C18H22N2O5	346.4	C[C@H]([C@@H]1CN(C1=O)C(=O)NCC=C)OC(=O)COCC2=CC=CC=C2	IC50 = 56850 nM	Poor binder
T18664	Monoglyceride lipase	B9YN1M	N-Morpholinylthiosalicylamide	Investigative	16245	C11H13NO2S	223.29	C1COCCN1C(=S)C2=CC=CC=C2O	IC50 = 60255.96 nM	Poor binder
T18664	Monoglyceride lipase	BALE68	Chembl4294988	Investigative	145993738	C25H34FNO3	415.5	CCCCCCCCCCC/C(=N\\O)/C1=C(C=CC(=C1)C2=CC(=C(C=C2)OC)F)O	IC50 = 53000 nM	Poor binder
T18664	Monoglyceride lipase	BAYH02	Chembl4280782	Investigative	145979233	C29H43NO3	453.7	CCCCCCCCCCCCCCC/C(=N\\O)/C1=C(C=CC(=C1)C2=CC=C(C=C2)OC)O	IC50 = 70000 nM	Poor binder
T18664	Monoglyceride lipase	BB32PW	[(1R)-1-[(3S)-2-Oxo-1-(prop-2-enylcarbamothioyl)azetidin-3-yl]ethyl] 2-phenylmethoxyacetate	Investigative	71575576	C18H22N2O4S	362.4	C[C@H]([C@@H]1CN(C1=O)C(=S)NCC=C)OC(=O)COCC2=CC=CC=C2	IC50 = 121700 nM	Poor binder
T18664	Monoglyceride lipase	BB9S6H	(Z)-N-(2-Hydroxyethyl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-(4-iodophenyl)pent-1-enyl]-5-oxocyclopentyl]hept-5-enamide	Investigative	118727547	C25H34INO5	555.4	C1[C@H]([C@@H]([C@H](C1=O)C/C=C\\CCCC(=O)NCCO)/C=C/[C@H](CCC2=CC=C(C=C2)I)O)O	IC50 ~ 100000 nM	Poor binder
T18664	Monoglyceride lipase	BEV35U	Morpholine-4-carbothioylsulfanylmethyl morpholine-4-carbodithioate	Investigative	15640477	C11H18N2O2S4	338.5	C1COCCN1C(=S)SCSC(=S)N2CCOCC2	IC50 = 102329.3 nM	Poor binder
T18664	Monoglyceride lipase	BGF08V	(3-Bromophenyl) 4-benzhydrylpiperazine-1-carbodithioate	Investigative	60166096	C24H23BrN2S2	483.5	C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=S)SC4=CC(=CC=C4)Br	IC50 = 95499.26 nM	Poor binder
T18664	Monoglyceride lipase	BHWU89	(3R)-1-(3,4-Dimethylphenyl)-5-oxo-N-[(4-oxo-3H-phthalazin-1-yl)methyl]pyrrolidine-3-carboxamide	Investigative	7626526	C22H22N4O3	390.4	CC1=C(C=C(C=C1)N2C[C@@H](CC2=O)C(=O)NCC3=NNC(=O)C4=CC=CC=C43)C	IC50 = 100000 nM	Poor binder
T18664	Monoglyceride lipase	BJB0W6	(Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]-N-[(2R)-1-hydroxypropan-2-yl]hept-5-enamide	Investigative	118727548	C26H37NO5	443.6	C[C@H](CO)NC(=O)CCC/C=C\\C[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](CCC2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T18664	Monoglyceride lipase	BK56JP	3,4-Dichloro-N-(2-phenylethyl)benzenecarbothioamide	Investigative	76333926	C15H13Cl2NS	310.2	C1=CC=C(C=C1)CCNC(=S)C2=CC(=C(C=C2)Cl)Cl	IC50 = 75857.76 nM	Poor binder
T18664	Monoglyceride lipase	BKF60J	[5-(4-Hydroxyphenyl)-1-phenylpyrazol-3-yl]-morpholin-4-ylmethanone	Investigative	137649377	C20H19N3O3	349.4	C1COCCN1C(=O)C2=NN(C(=C2)C3=CC=C(C=C3)O)C4=CC=CC=C4	IC50 = 61000 nM	Poor binder
T18664	Monoglyceride lipase	BKS3A8	1-(Benzotriazol-1-yl)-2-[4-(2-methylpropyl)phenyl]propan-1-one	Investigative	45784884	C19H21N3O	307.4	CC(C)CC1=CC=C(C=C1)C(C)C(=O)N2C3=CC=CC=C3N=N2	IC50 = 194984.46 nM	Poor binder
T18664	Monoglyceride lipase	BLU6C7	(Z)-N-(2-Hydroxyethyl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide	Investigative	118727545	C25H35NO5	429.5	C1[C@H]([C@@H]([C@H](C1=O)C/C=C\\CCCC(=O)NCCO)/C=C/[C@H](CCC2=CC=CC=C2)O)O	IC50 = 100000 nM	Poor binder
T18664	Monoglyceride lipase	BMG7P6	[5-(4-Hydroxyphenyl)-1-phenylpyrazol-3-yl]-(4-methylpiperazin-1-yl)methanone	Investigative	137637912	C21H22N4O2	362.4	CN1CCN(CC1)C(=O)C2=NN(C(=C2)C3=CC=C(C=C3)O)C4=CC=CC=C4	IC50 = 71000 nM	Poor binder
T18664	Monoglyceride lipase	BMZ19A	Ethyl 1-(4-chlorophenyl)-5-[3-(cyclohexylcarbamoyloxy)phenyl]pyrazole-3-carboxylate	Investigative	118736028	C25H26ClN3O4	467.9	CCOC(=O)C1=NN(C(=C1)C2=CC(=CC=C2)OC(=O)NC3CCCCC3)C4=CC=C(C=C4)Cl	IC50 = 83000 nM	Poor binder
T18664	Monoglyceride lipase	BN6T4H	[4-(Diethylcarbamoyl)phenyl] 4-benzhydrylpiperazine-1-carbodithioate	Investigative	60166099	C29H33N3OS2	503.7	CCN(CC)C(=O)C1=CC=C(C=C1)SC(=S)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4	IC50 = 69183.1 nM	Poor binder
T18664	Monoglyceride lipase	BNIO49	Chembl4277378	Investigative	145982453	C25H35NO3	397.5	CCCCCCCCCCC/C(=N\\O)/C1=C(C=CC(=C1)C2=CC=C(C=C2)OC)O	IC50 = 69000 nM	Poor binder
T18664	Monoglyceride lipase	BS91PC	(3R)-N-(1,3-Benzodioxol-5-ylmethyl)-1-[4-[(2-chlorophenyl)methoxy]phenyl]-5-oxopyrrolidine-3-carboxamide	Investigative	1532212	C26H23ClN2O5	478.9	C1[C@H](CN(C1=O)C2=CC=C(C=C2)OCC3=CC=CC=C3Cl)C(=O)NCC4=CC5=C(C=C4)OCO5	IC50 = 100000 nM	Poor binder
T18664	Monoglyceride lipase	BU9T1P	2,4-Dichloro-N-(2-phenylethyl)benzenecarbothioamide	Investigative	76319468	C15H13Cl2NS	310.2	C1=CC=C(C=C1)CCNC(=S)C2=C(C=C(C=C2)Cl)Cl	IC50 = 79432.82 nM	Poor binder
T18664	Monoglyceride lipase	BX0YR6	Chembl4289567	Investigative	145986609	C18H21NO3	299.4	CCCC/C(=N\\O)/C1=C(C=CC(=C1)C2=CC=C(C=C2)OC)O	IC50 = 119000 nM	Poor binder
T18664	Monoglyceride lipase	BYG7S5	3-(Octyloxy)Benzo[D]Isoxazole	Investigative	57400169	C15H21NO2	247.33	CCCCCCCCOC1=NOC2=CC=CC=C21	IC50 = 67900 nM	Poor binder
T18664	Monoglyceride lipase	D00NXA	Benzofuran-2-ylboronic acid	Investigative	2776266	C8H7BO3	161.95	B(C1=CC2=CC=CC=C2O1)(O)O	IC50 = 100000 nM	Poor binder
T18664	Monoglyceride lipase	D05GPK	Biphenyl-3-ylboronic acid	Investigative	2734315	C12H11BO2	198.03	B(C1=CC(=CC=C1)C2=CC=CC=C2)(O)O	IC50 = 71000 nM	Poor binder