TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T18876	Prostaglandin E2 receptor EP4	B0KH7D	4''-(6-Oxo-11,12-dihydro-6H-dibenzo[b,f]azocin-5-ylmethyl)-biphenyl-2-sulfonic acid phenylacetyl-amide	Investigative	9808508	C36H30N2O4S	586.7	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)NC(=O)CC6=CC=CC=C6	Ki ~ 100000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	B2L6AG	(E)-3-[2-(4-Methylsulfanyl-benzyl)-phenyl]-acrylic acid	Investigative	9817292	C17H16O2S	284.4	CSC1=CC=C(C=C1)CC2=CC=CC=C2/C=C/C(=O)O	Ki ~ 50000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	B2VGU9	2-[1-[2-(N-Benzoyl-4-methylanilino)ethyl]piperidin-4-yl]oxyacetic acid	Investigative	127029417	C23H28N2O4	396.5	CC1=CC=C(C=C1)N(CCN2CCC(CC2)OCC(=O)O)C(=O)C3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	B61TJN	N-(2-Thienylsulfonyl)-3'-(methylsulfonyl)biphenyl-2-propionamide	Investigative	21362869	C20H19NO5S3	449.6	CS(=O)(=O)C1=CC=CC(=C1)C2=CC=CC=C2CCC(=O)NS(=O)(=O)C3=CC=CS3	Ki ~ 100000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	B92FAC	1-[2-[4-[(6-Oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(3-phenylpropyl)urea	Investigative	9960839	C38H35N3O4S	629.8	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)NC(=O)NCCCC6=CC=CC=C6	Ki ~ 100000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	B94KFB	7-[(S)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid	Investigative	44290245	C19H33NO4	339.5	CCCCC[C@@H](/C=C/[C@@H]1CCC(=O)N1CCCCCCC(=O)O)O	EC50 ~ 100000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	BA3LM8	4-(2-(2-(4-Hydroxy-4-(1-propylcyclobutyl)butyl)-5-oxopyrazolidin-1-yl)ethyl)benzoic acid	Investigative	44444722	C23H34N2O4	402.5	CCCC1(CCC1)C(CCCN2CCC(=O)N2CCC3=CC=C(C=C3)C(=O)O)O	Ki ~ 50000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	BOD8P4	2-[1-[2-[N-(1,3-Benzodioxole-5-carbonyl)-4-methylanilino]ethyl]piperidin-4-yl]oxyacetic acid;hydrate;hydrochloride	Investigative	127047381	C24H31ClN2O7	495	CC1=CC=C(C=C1)N(CCN2CCC(CC2)OCC(=O)O)C(=O)C3=CC4=C(C=C3)OCO4.O.Cl	Ki ~ 50000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	BQ4S1E	1-[2-[4-[(6-Oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(2-thiophen-2-ylethyl)urea	Investigative	9938995	C35H31N3O4S2	621.8	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)NC(=O)NCCC6=CC=CS6	Ki ~ 100000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	BSR43T	Schembl20719106	Investigative	49850345	C21H18N2O4	362.4	CC(C)C1(C(=O)NC(=O)O1)C2=CC=C(NC2=O)C3=CC4=CC=CC=C4C=C3	IC50 ~ 50118.72 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	BSY72X	1-Butyl-3-[2-[4-[(6-oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonylurea	Investigative	9872741	C33H33N3O4S	567.7	CCCCNC(=O)NS(=O)(=O)C1=CC=CC=C1C2=CC=C(C=C2)CN3C4=CC=CC=C4CCC5=CC=CC=C5C3=O	Ki ~ 100000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	BU1Y2G	7-[(2S)-2-[(E,3R)-3-Hydroxyoct-1-enyl]-5-oxopyrrolidin-1-yl]heptanoic acid	Investigative	6453527	C19H33NO4	339.5	CCCCC[C@H](/C=C/[C@@H]1CCC(=O)N1CCCCCCC(=O)O)O	EC50 = 200000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	BV9AM7	1-Benzyl-1-[2-[4-[(6-oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(2-phenylethyl)urea	Investigative	15491230	C44H39N3O4S	705.9	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)N(CC6=CC=CC=C6)C(=O)NCCC7=CC=CC=C7	Ki ~ 100000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	BWA0M2	1-Benzyl-3-[2-[4-[(6-oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonylurea	Investigative	9916766	C36H31N3O4S	601.7	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)NC(=O)NCC6=CC=CC=C6	Ki ~ 100000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	BWE7Q9	1-Methyl-1-[2-[4-[(6-oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(2-phenylethyl)urea	Investigative	15491229	C38H35N3O4S	629.8	CN(C(=O)NCCC1=CC=CC=C1)S(=O)(=O)C2=CC=CC=C2C3=CC=C(C=C3)CN4C5=CC=CC=C5CCC6=CC=CC=C6C4=O	Ki ~ 100000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	BX2PY8	1-[2-[4-[(6-Oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(2-phenylethyl)urea	Investigative	9830442	C37H33N3O4S	615.7	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)NC(=O)NCCC6=CC=CC=C6	Ki ~ 100000 nM	Poor binder
T18876	Prostaglandin E2 receptor EP4	D0J9PG	AH6809	Investigative	119461	C17H14O5	298.29	CC(C)OC1=CC2=C(C=C1)C(=O)C3=C(O2)C=CC(=C3)C(=O)O	Ki ~ 100000 nM	Poor binder