TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T22274	Histone deacetylase 6	D0AZ3C	Imatinib	Approved	5291	C29H31N7O	493.6	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	D0M8FD	SNDX-275	Phase 2	4261	C21H20N4O3	376.4	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	D0W9NH	Tacedinaline	Discontinued in Phase 2	2746	C15H15N3O2	269.3	CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B03PZD	2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(6-phenylhexyl)acetamide	Investigative	136025984	C19H25N3O2S	359.5	CC1=CC(=O)NC(=N1)SCC(=O)NCCCCCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B0BH5F	S-[5-[(3S,6R,9S,12R)-6-[2-(2-Acetylsulfanylethoxy)ethyl]-3-benzyl-2,5,8,11-tetraoxo-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-9-yl]pentyl] ethanethioate	Investigative	71460412	C31H44N4O7S2	648.8	CC(=O)SCCCCC[C@H]1C(=O)N[C@@H](C(=O)N[C@H](C(=O)N2CCC[C@@H]2C(=O)N1)CC3=CC=CC=C3)CCOCCSC(=O)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B0GAH1	Pimelic Diphenylamide 106	Investigative	16070100	C20H25N3O2	339.4	CC1=CC=C(C=C1)NC(=O)CCCCCC(=O)NC2=CC=CC=C2N	IC50 ~ 80000 nM	Poor binder
T22274	Histone deacetylase 6	B0IP6E	N-[(2S)-1-[[6-(2-Amino-4-fluoroanilino)-6-oxohexyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide	Investigative	137657586	C31H34FN5O4	559.6	COC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)NCCCCCC(=O)NC4=C(C=C(C=C4)F)N	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B0OI4T	3-[3-[2-(3-Methylphenoxy)ethoxy]quinoxalin-2-yl]propanoic acid	Investigative	137651757	C20H20N2O4	352.4	CC1=CC(=CC=C1)OCCOC2=NC3=CC=CC=C3N=C2CCC(=O)O	IC50 = 180000 nM	Poor binder
T22274	Histone deacetylase 6	B0R4TM	2-{[2-(4-Tert-butylphenyl)-2-oxoethyl]sulfanyl}-6-methyl-3,4-dihydropyrimidin-4-one	Investigative	135497781	C17H20N2O2S	316.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B0Z8KT	(2E)-3-(3-Bromo-4-methoxyphenyl)-2-methoxyimino-N-(2-methylsulfanylethyl)propanamide	Investigative	51033161	C14H19BrN2O3S	375.28	COC1=C(C=C(C=C1)C/C(=N\\OC)/C(=O)NCCSC)Br	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B1CL9O	Thiophene-2-carboxylic acid (4-hydroxy-biphenyl-3-yl)-amide	Investigative	44447120	C17H13NO2S	295.4	C1=CC=C(C=C1)C2=CC(=C(C=C2)O)NC(=O)C3=CC=CS3	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B1Q7UK	N-Hydroxy-5-[3-(pent-4-enoylamino)propyl]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide	Investigative	70690302	C15H22N4O3S	338.4	C=CCCC(=O)NCCCN1CCC2=C(C1)SC(=N2)C(=O)NO	IC50 = 58670 nM	Poor binder
T22274	Histone deacetylase 6	B1SXO5	N-[4-[2-(4-Methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide	Investigative	56659403	C15H15N3O2S	301.4	CC1=NC(=NC=C1)SCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B1TSK2	N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[4-(propylaminocarbamoyl)anilino]propan-2-yl]-4-methoxybenzamide	Investigative	137635119	C29H31N5O4	513.6	CCCNNC(=O)C1=CC=C(C=C1)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)C4=CC=C(C=C4)OC	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B24FWP	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[3-(sulfamoylamino)propyl]benzamide	Investigative	134153768	C23H22F4N6O4S2	586.6	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCCNS(=O)(=O)N)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B25CPF	2-N-(2-Aminophenyl)-5-N-[4-methyl-3-[(5-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]thiophene-2,5-dicarboxamide	Investigative	44572539	C27H22N6O2S2	526.6	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(S2)C(=O)NC3=CC=CC=C3N)NC4=NC=C(S4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B2BE6I	6-Methylquinoline-8-thiol	Investigative	13008156	C10H9NS	175.25	CC1=CC2=C(C(=C1)S)N=CC=C2	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B2VLJ6	N-[4-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]acetamide	Investigative	136025842	C14H15N3O2S	289.35	CC1=CC(=O)NC(=N1)SCC2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B2YIB7	N-((R)-5-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)hexyl)butane-1-sulfonamide	Investigative	46907280	C28H49NO4S	495.8	CCCCS(=O)(=O)NCCCC[C@@H](C)[C@H]1CC[C@@H]\\2[C@@]1(CCC/C2=C\\C=C3C[C@H](C[C@@H](C3)O)O)C	IC50 = 101000 nM	Poor binder
T22274	Histone deacetylase 6	B3B6JM	3-(4-Benzyl-7-chloro-3-oxo-3,4-dihydroquinoxalin-2-yl)propanoic acid	Investigative	2385952	C18H15ClN2O3	342.8	C1=CC=C(C=C1)CN2C3=C(C=C(C=C3)Cl)N=C(C2=O)CCC(=O)O	IC50 = 150000 nM	Poor binder
T22274	Histone deacetylase 6	B3CIM1	3-(3-Bromo-4-methoxyphenyl)-N-(2-methylsulfanylethyl)-2-oxopropanamide	Investigative	57326510	C13H16BrNO3S	346.24	COC1=C(C=C(C=C1)CC(=O)C(=O)NCCSC)Br	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B3LS5D	(1,4-Dioxo-3,4-dihydrophthalazin-2(1H)-yl)acetic acid	Investigative	2378263	C10H8N2O4	220.18	C1=CC=C2C(=C1)C(=O)NN(C2=O)CC(=O)O	IC50 = 200000 nM	Poor binder
T22274	Histone deacetylase 6	B3QGR2	(2E)-3-(3-Bromo-4-hydroxyphenyl)-2-hydrazinylidene-N-(2-methylsulfanylethyl)propanamide	Investigative	57326611	C12H16BrN3O2S	346.25	CSCCNC(=O)/C(=N/N)/CC1=CC(=C(C=C1)O)Br	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B3UH6L	N-[(2S)-1-[[4-(Anilinocarbamoyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide	Investigative	137661927	C33H31N5O4	561.6	COC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)NCC4=CC=C(C=C4)C(=O)NNC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B3UK0O	Carbamic acid,N-[[4-[[(4-amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]-,methyl ester	Investigative	25032862	C22H21N3O3	375.4	COC(=O)NCC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=CC=C3)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B40XIT	N-(2-Chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide	Investigative	137657892	C14H7ClF12N2O3	514.65	C1=CC=C(C(=C1)NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)Cl	Ki ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B43ATQ	N1-(2-Aminophenyl)-N4-(3-(methyl(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)terephthalamide	Investigative	42625892	C30H25N7O2	515.6	CN(C1=CC=CC(=C1)NC2=NC=CC(=N2)C3=CN=CC=C3)C(=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC=C5N	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B4LM3X	(4-Oxo[1]benzofuro[3,2-d]pyrimidin-3(4H)-yl)acetic acid	Investigative	4962437	C12H8N2O4	244.2	C1=CC=C2C(=C1)C3=C(O2)C(=O)N(C=N3)CC(=O)O	IC50 = 51000 nM	Poor binder
T22274	Histone deacetylase 6	B4YZ2S	6-(Acetyl-hydroxy-amino)-hexanoic acid phenylamide	Investigative	44359800	C14H20N2O3	264.32	CC(=O)N(CCCCCC(=O)NC1=CC=CC=C1)O	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B54MQD	(2E)-3-(3-Bromo-4-methoxyphenyl)-N-[2-[2-[[(2E)-3-(3-bromo-4-methoxyphenyl)-2-hydrazinylidenepropanoyl]amino]ethyldisulfanyl]ethyl]-2-hydrazinylidenepropanamide	Investigative	57326614	C24H30Br2N6O4S2	690.5	COC1=C(C=C(C=C1)C/C(=N\\N)/C(=O)NCCSSCCNC(=O)/C(=N/N)/CC2=CC(=C(C=C2)OC)Br)Br	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B59SUW	Azumamide D	Investigative	16095113	C25H35N5O5	485.6	C[C@H]1[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)C)C)CC2=CC=CC=C2)C/C=C\\CCC(=O)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B5F4EH	N-((R)-5-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)hexyl)trifluoromethanesulfonamide	Investigative	46907198	C25H40F3NO4S	507.7	C[C@H](CCCCNS(=O)(=O)C(F)(F)F)[C@H]1CC[C@@H]\\2[C@@]1(CCC/C2=C\\C=C3C[C@H](C[C@@H](C3)O)O)C	IC50 = 153000 nM	Poor binder
T22274	Histone deacetylase 6	B5GI6E	N1-(2-Aminophenyl)-N4-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)terephthalamide	Investigative	44572385	C30H25N7O2	515.6	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)C(=O)NC3=CC=CC=C3N)NC4=NC=C(C=N4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B5H4IM	(R)-N-(2-Aminophenyl)-6-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)heptanamide	Investigative	25207860	C31H46N2O3	494.7	C[C@H](CCCCC(=O)NC1=CC=CC=C1N)[C@H]2CC[C@@H]\\3[C@@]2(CCC/C3=C\\C=C4C[C@H](C[C@@H](C4)O)O)C	IC50 = 81000 nM	Poor binder
T22274	Histone deacetylase 6	B5HIZ3	N-[4-[2-[(4-Methyl-6-oxo-1H-pyridin-2-yl)oxy]acetyl]phenyl]acetamide	Investigative	56673261	C16H16N2O4	300.31	CC1=CC(=O)NC(=C1)OCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B5I3GW	N-[(2S)-1-(1H-Indol-3-yl)-3-[4-[(E)-3-oxo-3-(2-propylhydrazinyl)prop-1-enyl]phenoxy]propan-2-yl]-4-methoxybenzamide	Investigative	137640258	C31H34N4O4	526.6	CCCNNC(=O)/C=C/C1=CC=C(C=C1)OC[C@H](CC2=CNC3=CC=CC=C32)NC(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B5REF6	3-(6,7-Dimethoxy-4-oxoquinazolin-3(4H)-yl)propanoic acid	Investigative	9533923	C13H14N2O5	278.26	COC1=C(C=C2C(=C1)C(=O)N(C=N2)CCC(=O)O)OC	IC50 = 95000 nM	Poor binder
T22274	Histone deacetylase 6	B5YA1D	2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(2-methylphenyl)octanediamide	Investigative	137647616	C15H10F12N2O3	494.23	CC1=CC=CC=C1NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F	Ki ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B6K7LT	Benzyl (2S)-4-[5-[(2-amino-5-phenylphenyl)carbamoyl]pyridin-2-yl]-2-methylpiperazine-1-carboxylate	Investigative	16663079	C31H31N5O3	521.6	C[C@H]1CN(CCN1C(=O)OCC2=CC=CC=C2)C3=NC=C(C=C3)C(=O)NC4=C(C=CC(=C4)C5=CC=CC=C5)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B6N7XK	N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[[6-oxo-6-(2-propylhydrazinyl)hexyl]amino]propan-2-yl]-4-methoxybenzamide	Investigative	137638917	C28H37N5O4	507.6	CCCNNC(=O)CCCCCNC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)C3=CC=C(C=C3)OC	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B76NHE	2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(4-phenylbutyl)acetamide	Investigative	136086923	C17H21N3O2S	331.4	CC1=CC(=O)NC(=N1)SCC(=O)NCCCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B7IC9L	N2-(2-Aminophenyl)-N5-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)thiophene-2,5-dicarboxamide	Investigative	44572430	C28H23N7O2S	521.6	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(S2)C(=O)NC3=CC=CC=C3N)NC4=NC=C(C=N4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B7JEZ8	1-((4-Hydroxy-6-methylpyrimidin-2-yl)thio)propan-2-one	Investigative	135462117	C8H10N2O2S	198.24	CC1=CC(=O)NC(=N1)SCC(=O)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B7QJ2A	N-(7-Amino-7-oxoheptyl)-2-(N-phenylanilino)pyrimidine-5-carboxamide	Investigative	58536981	C24H27N5O2	417.5	C1=CC=C(C=C1)N(C2=CC=CC=C2)C3=NC=C(C=N3)C(=O)NCCCCCCC(=O)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B7RQK5	N-[(2S)-1-[[4-[(Cyclopentylamino)carbamoyl]phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide	Investigative	137652359	C32H35N5O4	553.7	COC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)NCC4=CC=C(C=C4)C(=O)NNC5CCCC5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B81YTQ	N-[4-[2-(3-Hydroxyphenyl)sulfanylacetyl]phenyl]acetamide	Investigative	56666337	C16H15NO3S	301.4	CC(=O)NC1=CC=C(C=C1)C(=O)CSC2=CC=CC(=C2)O	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B8YM4H	N-[4-(Dimethylamino)phenyl]-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide	Investigative	137631704	C16H13F12N3O3	523.27	CN(C)C1=CC=C(C=C1)NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F	Ki ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B91PWS	(1R,3As,4E,7aR)-4-[2-[(3R,5R)-3,5-dihydroxycyclohexylidene]ethylidene]-7a-methyl-1-[(2R)-6-(sulfamoylamino)hexan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-indene	Investigative	46906597	C24H42N2O4S	454.7	C[C@H](CCCCNS(=O)(=O)N)[C@H]1CC[C@@H]\\2[C@@]1(CCC/C2=C\\C=C3C[C@H](C[C@@H](C3)O)O)C	IC50 = 50400 nM	Poor binder
T22274	Histone deacetylase 6	B93MKY	N-[4-[1-Hydroxy-2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]ethyl]phenyl]acetamide	Investigative	136025843	C15H17N3O3S	319.4	CC1=CC(=O)NC(=N1)SCC(C2=CC=C(C=C2)NC(=O)C)O	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B9GB4J	Benzamide-type inhibitor, 4	Investigative	23648260	C25H22N4O3S	458.5	C1=CC(=CN=C1)COC(=O)NCC2=CC=C(C=C2)C(=O)NC3=C(C=CC(=C3)C4=CC=CS4)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	B9H3VQ	(3S,6Z,9S,12R,16S)-6-Ethylidene-16-[(E)-4-methylsulfanylbut-1-enyl]-9-(methylsulfanylmethyl)-3,12-di(propan-2-yl)-1-oxa-4,7,10-triazacyclohexadecane-2,5,8,11,14-pentone	Investigative	70695508	C27H43N3O6S2	569.8	C/C=C\\1/C(=O)N[C@H](C(=O)O[C@@H](CC(=O)C[C@@H](C(=O)N[C@@H](C(=O)N1)CSC)C(C)C)/C=C/CCSC)C(C)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B9TCH1	(4-(2-Aminophenylcarbamoyl)benzylamino)methyl nicotinate	Investigative	44572384	C21H20N4O3	376.4	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNCOC(=O)C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	B9TXG7	3-(1-Methyl-1H-benzoimidazol-2-yl)-propionic acid	Investigative	3151732	C11H12N2O2	204.22	CN1C2=CC=CC=C2N=C1CCC(=O)O	IC50 = 100000 nM	Poor binder
T22274	Histone deacetylase 6	BAD74G	N-(3-Chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide	Investigative	137656303	C14H7ClF12N2O3	514.65	C1=CC(=CC(=C1)Cl)NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F	Ki ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BAH3G7	3-(4-Methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)propanoic acid	Investigative	252888	C12H12N2O3	232.23	CN1C2=CC=CC=C2N=C(C1=O)CCC(=O)O	IC50 = 65000 nM	Poor binder
T22274	Histone deacetylase 6	BAI6J8	3-(1,3-Benzothiazol-2-yl)propanoic acid	Investigative	770976	C10H9NO2S	207.25	C1=CC=C2C(=C1)N=C(S2)CCC(=O)O	IC50 = 180000 nM	Poor binder
T22274	Histone deacetylase 6	BB0C3R	6-(3-Amino-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-7-yl)-N-hydroxyhex-5-ynamide	Investigative	72204850	C22H22N4O3	390.4	CN1C2=C(C=C(C=C2)C#CCCCC(=O)NO)C(=NC(C1=O)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BBC03O	N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[[4-[(pentylamino)carbamoyl]phenyl]methylamino]propan-2-yl]-4-methoxybenzamide	Investigative	137653295	C32H37N5O4	555.7	CCCCCNNC(=O)C1=CC=C(C=C1)CNC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BBEK28	(2E)-3-(3-Bromo-4-hydroxyphenyl)-2-methoxyimino-N-(2-methylsulfanylethyl)propanamide	Investigative	57326321	C13H17BrN2O3S	361.26	CO/N=C(\\CC1=CC(=C(C=C1)O)Br)/C(=O)NCCSC	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BC54SO	2-[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one	Investigative	136086920	C15H14N2O4S	318.3	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC3=C(C=C2)OCCO3	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BCK3G5	N-(2-Aminophenyl)-4-[[[(4S,5S)-4,5-diphenyl-1,3-oxazolidin-2-ylidene]amino]methyl]benzamide	Investigative	137125260	C29H26N4O2	462.5	C1=CC=C(C=C1)[C@H]2[C@@H](OC(=NCC3=CC=C(C=C3)C(=O)NC4=CC=CC=C4N)N2)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BCK60Y	N-[(2S)-1-[[4-(Butylaminocarbamoyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide	Investigative	137633768	C31H35N5O4	541.6	CCCCNNC(=O)C1=CC=C(C=C1)CNC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BCM42B	N-(2-Aminophenyl)-11-[(7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl]undecanamide	Investigative	127034722	C35H50N2O3	546.8	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@@H](CC4=C3C=CC(=C4)O)CCCCCCCCCCC(=O)NC5=CC=CC=C5N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BD19BW	3-[3-[(1-Methylimidazol-2-yl)methoxy]quinoxalin-2-yl]propanoic acid	Investigative	137651315	C16H16N4O3	312.32	CN1C=CN=C1COC2=NC3=CC=CC=C3N=C2CCC(=O)O	IC50 = 140000 nM	Poor binder
T22274	Histone deacetylase 6	BD3EG1	N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[[7-oxo-7-(2-propylhydrazinyl)heptyl]amino]propan-2-yl]-4-methoxybenzamide	Investigative	137660171	C29H39N5O4	521.7	CCCNNC(=O)CCCCCCNC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)C3=CC=C(C=C3)OC	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BDCZ86	2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamide	Investigative	135441620	C15H17N3O2S	303.4	CC1=CC(=O)NC(=N1)SCC(=O)NCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BDR0H9	8-(Acetyl-hydroxy-amino)-octanoic acid phenylamide	Investigative	44359673	C16H24N2O3	292.37	CC(=O)N(CCCCCCCC(=O)NC1=CC=CC=C1)O	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BEPZ71	Chembl4215552	Investigative	5111969	C13H12N4O3	272.26	C1CCN2C(=C(C3=C2C(=O)N(C=N3)CC(=O)O)C#N)C1	IC50 = 77000 nM	Poor binder
T22274	Histone deacetylase 6	BEX6B7	(7,9-Dimethyl-4-oxopyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl)acetic acid	Investigative	4962314	C13H11N3O3S	289.31	CC1=CC(=NC2=C1C3=C(S2)C(=O)N(C=N3)CC(=O)O)C	IC50 = 190000 nM	Poor binder
T22274	Histone deacetylase 6	BF4SB0	N'-Hydroxy-N-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)hexanediamide	Investigative	72204666	C22H24N4O4	408.4	CN1C2=CC=CC=C2C(=NC(C1=O)NC(=O)CCCCC(=O)NO)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BF5DK4	2-(4-Hydroxybenzylidene)-1-benzofuran-3(2H)-one	Investigative	1798422	C15H10O3	238.24	C1=CC=C2C(=C1)C(=O)/C(=C/C3=CC=C(C=C3)O)/O2	IC50 = 135900 nM	Poor binder
T22274	Histone deacetylase 6	BFI52G	4-[2-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]ethylamino]benzoic acid	Investigative	134144836	C31H30N4O5	538.6	C1/C=C/COCC2=C(C=CC(=C2)NC3=NC=CC(=N3)C4=CC=CC(=C4)CO1)OCCNC5=CC=C(C=C5)C(=O)O	IC50 = 64000 nM	Poor binder
T22274	Histone deacetylase 6	BG09QH	N-{4-[2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetyl]-phenyl}-acetamide	Investigative	1108280	C16H17N3O2S	315.4	CC1=CC(=NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BH0F5K	N2-(2-Aminophenyl)-N5-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)thiophene-2,5-dicarboxamide	Investigative	44572538	C26H20N6O2S2	512.6	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(S2)C(=O)NC3=CC=CC(=C3)NC4=NC=C(S4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BH4RI7	N-[(2S)-1-[[6-(2-Amino-5-thiophen-2-ylanilino)-6-oxohexyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide	Investigative	137633138	C35H37N5O4S	623.8	COC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)NCCCCCC(=O)NC4=C(C=CC(=C4)C5=CC=CS5)N	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BH7TL1	3-(5-Chloro-1,3-benzothiazol-2-yl)propanoic acid	Investigative	7131995	C10H8ClNO2S	241.69	C1=CC2=C(C=C1Cl)N=C(S2)CCC(=O)O	IC50 = 55000 nM	Poor binder
T22274	Histone deacetylase 6	BI3L7C	N2-(2-Aminophenyl)-N5-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)pyridine-2,5-dicarboxamide	Investigative	44572491	C27H21N7O2S	507.6	C1=CC=C(C(=C1)N)NC(=O)C2=NC=C(C=C2)C(=O)NC3=CC=CC(=C3)NC4=NC=C(S4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BI6ZB1	N-Methyl-N-[4-[2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]acetamide	Investigative	136025986	C16H17N3O3S	331.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)N(C)C(=O)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BIH41V	(1R,14S,17R,23S)-23-Benzyl-4-oxa-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone	Investigative	71458560	C27H38N4O5S2	562.7	C1CC[C@H]2C(=O)N[C@H](CCOCCSSCC1)C(=O)N[C@H](C(=O)N3CCC[C@@H]3C(=O)N2)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BJ1OD3	2-(Tert-butylcarbonylmethylthio)-4-hydroxy-6-methylpyrimidine	Investigative	135473106	C11H16N2O2S	240.32	CC1=CC(=O)NC(=N1)SCC(=O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BK7B5Y	N-Butyl-11-[(7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl]-N-hydroxyundecanamide	Investigative	127034902	C33H53NO4	527.8	CCCCN(C(=O)CCCCCCCCCC[C@@H]1CC2=C(C=CC(=C2)O)[C@@H]3[C@@H]1[C@@H]4CC[C@@H]([C@]4(CC3)C)O)O	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BL5N1X	Nampt-IN-3	Investigative	137634086	C29H25N7O2	503.6	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CN3C=C(N=N3)C4=CC=C(C=C4)C(=O)NCC5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BL9F0X	Hdac3-IN-T326	Investigative	71721558	C21H18N6O3S	434.5	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(S2)C3=CN(N=N3)CCC4=CC(=CC=C4)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BLBA30	2-[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone	Investigative	135449197	C14H14N2O3S	290.34	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)OC	IC50 = 60900 nM	Poor binder
T22274	Histone deacetylase 6	BLK41U	(6-Bromo-4-oxoquinazolin-3(4H)-yl)acetic acid	Investigative	1187508	C10H7BrN2O3	283.08	C1=CC2=C(C=C1Br)C(=O)N(C=N2)CC(=O)O	IC50 = 200000 nM	Poor binder
T22274	Histone deacetylase 6	BLS1X3	N-Hydroxy-5-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-7-yl)pent-4-ynamide	Investigative	72204473	C21H19N3O3	361.4	CN1C(=O)CN=C(C2=C1C=CC(=C2)C#CCCC(=O)NO)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BM74NP	N-(2-Aminophenyl)-4-[[[(2S)-3-(1H-indol-3-yl)-2-[(4-methoxybenzoyl)amino]propanoyl]amino]methyl]benzamide	Investigative	137645675	C33H31N5O4	561.6	COC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)NCC4=CC=C(C=C4)C(=O)NC5=CC=CC=C5N	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BMC98T	2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-(4-fluorophenyl)-N'-hydroxyoctanediamide	Investigative	137649646	C14H7F13N2O3	498.2	C1=CC(=CC=C1NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)F	Ki ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BMH13O	Ethyl 4-((2-amino-5-(thiophen-2-yl)phenyl)carbamoyl)benzylcarbamate	Investigative	25155956	C21H21N3O3S	395.5	CCOC(=O)NCC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=CS3)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BMH78R	(2E)-3-(3-Bromo-4-methoxyphenyl)-2-hydrazinylidene-N-(2-methylsulfanylethyl)propanamide	Investigative	57326612	C13H18BrN3O2S	360.27	COC1=C(C=C(C=C1)C/C(=N\\N)/C(=O)NCCSC)Br	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BMZ5H3	2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(4-methoxyphenyl)octanediamide	Investigative	137652670	C15H10F12N2O4	510.23	COC1=CC=C(C=C1)NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F	Ki ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BN5Z1P	N2-(2-Aminophenyl)-N5-(4-methyl-3-(5-(pyridin-3-yl)thiazol-2-ylamino)phenyl)pyridine-2,5-dicarboxamide	Investigative	44572537	C28H23N7O2S	521.6	CC1=C(C=C(C=C1)NC(=O)C2=CN=C(C=C2)C(=O)NC3=CC=CC=C3N)NC4=NC=C(S4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BN7MF9	Methyl 4-((2-amino-5-(thiophen-2-yl)phenyl)carbamoyl)benzylcarbamate	Investigative	44447194	C20H19N3O3S	381.4	COC(=O)NCC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=CS3)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BNP3Y7	N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide	Investigative	71721946	C21H19N5OS	389.5	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)C3=CN(N=N3)CCC4=CSC=C4	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BNX0H8	N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[[4-(propylaminocarbamoyl)phenyl]methylamino]propan-2-yl]-4-methoxybenzamide	Investigative	137642900	C30H33N5O4	527.6	CCCNNC(=O)C1=CC=C(C=C1)CNC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BO5I0U	N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)oxy]acetyl]phenyl]acetamide	Investigative	136086924	C15H15N3O4	301.3	CC1=CC(=O)NC(=N1)OCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 = 88000 nM	Poor binder
T22274	Histone deacetylase 6	BO7B1P	(2E)-3-(3-Bromo-4-methoxyphenyl)-N-[2-[2-[[(2E)-3-(3-bromo-4-methoxyphenyl)-2-methoxyiminopropanoyl]amino]ethyldisulfanyl]ethyl]-2-methoxyiminopropanamide	Investigative	13873842	C26H32Br2N4O6S2	720.5	COC1=C(C=C(C=C1)C/C(=N\\OC)/C(=O)NCCSSCCNC(=O)/C(=N/OC)/CC2=CC(=C(C=C2)OC)Br)Br	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BOE16X	1-[2-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]ethyl]piperidine-4-carboxylic acid	Investigative	134136880	C30H34N4O5	530.6	C1CN(CCC1C(=O)O)CCOC2=C3COC/C=C/COCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BOF9Z6	[4-(4-Amino-biphenyl-3-ylcarbamoyl)-benzyl]-carbamic acid pyridin-3-ylmethyl ester	Investigative	25155417	C27H24N4O3	452.5	C1=CC=C(C=C1)C2=CC(=C(C=C2)N)NC(=O)C3=CC=C(C=C3)CNC(=O)OCC4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BP2N0X	N-((R)-4-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)pentyl)methanesulfonamide	Investigative	46907196	C24H41NO4S	439.7	C[C@H](CCCNS(=O)(=O)C)[C@H]1CC[C@@H]\\2[C@@]1(CCC/C2=C\\C=C3C[C@H](C[C@@H](C3)O)O)C	IC50 = 71300 nM	Poor binder
T22274	Histone deacetylase 6	BP76KJ	3-[3-(Phenylsulfanyl)-2-quinoxalinyl]propanoic acid	Investigative	82017359	C17H14N2O2S	310.4	C1=CC=C(C=C1)SC2=NC3=CC=CC=C3N=C2CCC(=O)O	IC50 = 60000 nM	Poor binder
T22274	Histone deacetylase 6	BPRY15	Methyl 2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)acetate	Investigative	135412048	C8H10N2O3S	214.24	CC1=CC(=O)NC(=N1)SCC(=O)OC	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BQA14N	N-(2-Amino-5-(thiophen-2-yl)phenyl)-6-(2-oxo-1-oxa-3,8-diazaspiro[4.5]decan-8-yl)nicotinamide	Investigative	24744325	C23H23N5O3S	449.5	C1CN(CCC12CNC(=O)O2)C3=NC=C(C=C3)C(=O)NC4=C(C=CC(=C4)C5=CC=CS5)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BR9PK4	Diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzylamino)methylphosphonate	Investigative	42601485	C23H28N3O4PS	473.5	CCOP(=O)(CNCC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=CS3)N)OCC	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BU2T0V	Methyl 7-anilino-7-oxoheptyl(hydroxy)carbamate	Investigative	44359814	C15H22N2O4	294.35	COC(=O)N(CCCCCCC(=O)NC1=CC=CC=C1)O	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BULF09	N-(2-Amino-5-thiophen-2-ylphenyl)benzamide	Investigative	44454144	C17H14N2OS	294.4	C1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=CS3)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BV3ON1	Chembl4173739	Investigative	145952088	C20H25Cl2N3O	394.3	C1=CC=C(C(=C1)N)NC(=O)CCCC2=CC=C(C=C2)N(CCCl)CCCl	IC50 ~ 160000 nM	Poor binder
T22274	Histone deacetylase 6	BV4QB9	Chembl4244181	Investigative	145982591	C27H30N2O4	446.5	CC/C(=C(\\C1=CC=C(C=C1)O)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=C(C=C3)C(=O)NO	IC50 = 71900 nM	Poor binder
T22274	Histone deacetylase 6	BW25YN	3-[2-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]ethylamino]benzoic acid	Investigative	134157542	C31H30N4O5	538.6	C1/C=C/COCC2=C(C=CC(=C2)NC3=NC=CC(=N3)C4=CC=CC(=C4)CO1)OCCNC5=CC=CC(=C5)C(=O)O	IC50 = 53000 nM	Poor binder
T22274	Histone deacetylase 6	BW3BR4	Chembl4245766	Investigative	145983813	C26H27N3O5	461.5	CC(C)C1=CC(=C(C=C1O)O)C(=O)N2CCC3=C2C=CC(=C3)NCC4=CC=C(C=C4)C(=O)NO	IC50 = 74400 nM	Poor binder
T22274	Histone deacetylase 6	BW4IX7	Azumamide A	Investigative	16095102	C27H39N5O5	513.6	C[C@H]1[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)C(C)C)C)CC2=CC=CC=C2)C/C=C\\CCC(=O)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BW53QM	N-[4-[2-(4-Methoxy-6-methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide	Investigative	56673234	C16H17N3O3S	331.4	CC1=CC(=NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C)OC	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BW6M0T	N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[[8-oxo-8-(2-propylhydrazinyl)octyl]amino]propan-2-yl]-4-methoxybenzamide	Investigative	137659196	C30H41N5O4	535.7	CCCNNC(=O)CCCCCCCNC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)C3=CC=C(C=C3)OC	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BW7C9A	2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(3-methylphenyl)octanediamide	Investigative	137658785	C15H10F12N2O3	494.23	CC1=CC(=CC=C1)NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F	Ki ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BW7UJ5	4-[2-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]ethoxy]benzoic acid	Investigative	134152624	C31H29N3O6	539.6	C1/C=C/COCC2=C(C=CC(=C2)NC3=NC=CC(=N3)C4=CC=CC(=C4)CO1)OCCOC5=CC=C(C=C5)C(=O)O	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BWG03J	(E)-N-(2-Aminophenyl)-3-[4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluorophenyl]prop-2-enamide	Investigative	134147087	C28H21F4N5O2S	567.6	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)/C=C/C(=O)NC3=CC=CC=C3N)F)C4=CC(=C(C=C4)C#N)C(F)(F)F)C	IC50 = 60000 nM	Poor binder
T22274	Histone deacetylase 6	BWZ3L6	(S)-Benzyl 4-(5-(2-aminophenylcarbamoyl)pyridin-2-yl)-2-methylpiperazine-1-carboxylate	Investigative	16066811	C25H27N5O3	445.5	C[C@H]1CN(CCN1C(=O)OCC2=CC=CC=C2)C3=NC=C(C=C3)C(=O)NC4=CC=CC=C4N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	BXWV29	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[6-(3-hydroxy-2-oxopyridin-1-yl)hexyl]benzamide	Investigative	134142119	C31H29F4N5O4S	643.7	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCCCCCN3C=CC=C(C3=O)O)F)C4=CC(=C(C=C4)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	BY2O3L	N1-(2-Aminophenyl)-N8-(biphenyl-3-yl)octanediamide	Investigative	44591285	C26H29N3O2	415.5	C1=CC=C(C=C1)C2=CC(=CC=C2)NC(=O)CCCCCCC(=O)NC3=CC=CC=C3N	IC50 = 50000 nM	Poor binder
T22274	Histone deacetylase 6	BY9H6R	N-((R)-5-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)hexyl)methanesulfonamide	Investigative	46907197	C25H43NO4S	453.7	C[C@H](CCCCNS(=O)(=O)C)[C@H]1CC[C@@H]\\2[C@@]1(CCC/C2=C\\C=C3C[C@H](C[C@@H](C3)O)O)C	IC50 = 191000 nM	Poor binder
T22274	Histone deacetylase 6	BZ59WF	(R)-7-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)-N-methyl-2-oxooctanamide	Investigative	46906643	C27H43NO4	445.6	C[C@H](CCCCC(=O)C(=O)NC)[C@H]1CC[C@@H]\\2[C@@]1(CCC/C2=C\\C=C3C[C@H](C[C@@H](C3)O)O)C	IC50 = 64000 nM	Poor binder
T22274	Histone deacetylase 6	BZ60AG	3-[3-(2-Pyridin-2-yloxyethoxy)quinoxalin-2-yl]propanoic acid	Investigative	137633927	C18H17N3O4	339.3	C1=CC=C2C(=C1)N=C(C(=N2)OCCOC3=CC=CC=N3)CCC(=O)O	IC50 = 110000 nM	Poor binder
T22274	Histone deacetylase 6	BZY5J3	N2-(2-Aminophenyl)-N5-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)pyridine-2,5-dicarboxamide	Investigative	44572429	C29H24N8O2	516.6	CC1=C(C=C(C=C1)NC(=O)C2=CN=C(C=C2)C(=O)NC3=CC=CC=C3N)NC4=NC=C(C=N4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	D01BCK	N-hydroxy-1-naphthamide	Investigative	23382	C11H9NO2	187.19	C1=CC=C2C(=C1)C=CC=C2C(=O)NO	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	D03HNC	N-hydroxy-4-(naphthalen-1-yl)benzamide	Investigative	17748273	C17H13NO2	263.29	C1=CC=C2C(=C1)C=CC=C2C3=CC=C(C=C3)C(=O)NO	IC50 = 55000 nM	Poor binder
T22274	Histone deacetylase 6	D04UVL	N-(2-aminophenyl)nicotinamide	Investigative	1133083	C12H11N3O	213.23	C1=CC=C(C(=C1)N)NC(=O)C2=CN=CC=C2	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	D05QBX	Biphenyl-3-carboxylic acid hydroxyamide	Investigative	44369352	C13H11NO2	213.23	C1=CC=C(C=C1)C2=CC(=CC=C2)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T22274	Histone deacetylase 6	D09SUO	splitomicin	Investigative	5269	C13H10O2	198.22	C1CC(=O)OC2=C1C3=CC=CC=C3C=C2	IC50 ~ 75000 nM	Poor binder
T22274	Histone deacetylase 6	D0E0TA	N-(4-hydroxybiphenyl-3-yl)benzamide	Investigative	44454650	C19H15NO2	289.3	C1=CC=C(C=C1)C2=CC(=C(C=C2)O)NC(=O)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	D0E9DD	AZUMAMIDE E	Investigative	16095101	C27H38N4O6	514.6	C[C@H]1[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)C(C)C)C)CC2=CC=CC=C2)C/C=C\\CCC(=O)O	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	D0M1ZI	AZUMAMIDE B	Investigative	16095112	C27H39N5O6	529.6	C[C@H]1[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)C(C)C)C)CC2=CC=C(C=C2)O)C/C=C\\CCC(=O)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	D0M9LJ	N-(4-aminobiphenyl-3-yl)nicotinamide	Investigative	44454415	C18H15N3O	289.3	C1=CC=C(C=C1)C2=CC(=C(C=C2)N)NC(=O)C3=CN=CC=C3	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	D0MD7H	N-(4-aminobiphenyl-3-yl)benzamide	Investigative	44454143	C19H16N2O	288.3	C1=CC=C(C=C1)C2=CC(=C(C=C2)N)NC(=O)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	D0Q2GM	N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide	Investigative	44454416	C16H13N3OS	295.4	C1=CC(=CN=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=CS3)N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	D0Q9PO	AZUMAMIDE C	Investigative	16095114	C27H38N4O7	530.6	C[C@H]1[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)C(C)C)C)CC2=CC=C(C=C2)O)C/C=C\\CCC(=O)O	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	D0U8FC	N-(2-aminophenyl)benzamide	Investigative	759408	C13H12N2O	212.25	C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N	IC50 ~ 50000 nM	Poor binder
T22274	Histone deacetylase 6	D0V1HA	N-hydroxy-3-(naphthalen-1-yl)acrylamide	Investigative	24880249	C13H11NO2	213.23	C1=CC=C2C(=C1)C=CC=C2/C=C/C(=O)NO	IC50 = 82000 nM	Poor binder