TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T23995 Protein kinase C theta B3AX7F 8-Bromo-4-(3-chloro-4-fluoroanilino)-6-[(1-methylimidazol-4-yl)methylamino]quinoline-3-carbonitrile Investigative 17758574 C21H15BrClFN6 485.7 CN1C=C(N=C1)CNC2=CC3=C(C(=CN=C3C(=C2)Br)C#N)NC4=CC(=C(C=C4)F)Cl IC50 ~ 50000 nM Poor binder T23995 Protein kinase C theta B9OES1 1-(3-(8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea Investigative 11755812 C26H20F3N7O 503.5 C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CN4C=CN=C4C(=N3)NCC5=CC=NC=C5 IC50 = 50000 nM Poor binder T23995 Protein kinase C theta BG7Y0L Xanthohumol Investigative 639665 C21H22O5 354.4 CC(=CCC1=C(C(=C(C=C1O)OC)C(=O)/C=C/C2=CC=C(C=C2)O)O)C IC50 ~ 100000 nM Poor binder T23995 Protein kinase C theta BLEA34 9-(Oxetan-3-ylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one Investigative 118721545 C13H14N4O3 274.28 C1C(CO1)NC2=CC3=C(C=C2)OCC4=NNC(=O)CN43 IC50 ~ 50000 nM Poor binder T23995 Protein kinase C theta BM12FH N-(2-Oxo-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-9-yl)-2-piperidin-4-ylacetamide Investigative 118721559 C17H21N5O3 343.4 C1CNCCC1CC(=O)NC2=CC3=C(C=C2)OCC4=NNC(=O)CN43 IC50 ~ 50000 nM Poor binder T23995 Protein kinase C theta BX5NO4 9-(Azetidin-3-ylamino)-1-phenyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one Investigative 118721563 C19H19N5O2 349.4 C1C(CN1)NC2=CC3=C(C=C2)OCC4=NNC(=O)C(N43)C5=CC=CC=C5 IC50 ~ 50000 nM Poor binder