TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T25200	Ribonuclease L	B35XTY	4-(3-(1-Acetylamino-2,2,2-trichloro-ethyl)-thioureido)-benzoic acid butyl ester	Investigative	2887294	C16H20Cl3N3O3S	440.8	CCCCOC(=O)C1=CC=C(C=C1)NC(=S)NC(C(Cl)(Cl)Cl)NC(=O)C	EC50 = 99000 nM	Poor binder
T25200	Ribonuclease L	B6Q1MW	[(2R,3S,4R,5S)-5-(6-Aminopurin-9-yl)-3-[[(2R,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxyoxolan-2-yl]methyl [(2R,3S,4R,5S)-5-(6-aminopurin-9-yl)-4-hydroxy-2-phosphonooxyoxolan-3-yl] hydrogen phosphate	Investigative	46874270	C29H36N15O19P3	991.6	C1=NC(=C2C(=N1)N(C=N2)[C@@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O[C@H]4[C@H]([C@H](O[C@@H]4OP(=O)(O)O)N5C=NC6=C(N=CN=C65)N)O)OP(=O)(O)OC[C@@H]7[C@H]([C@H](C(O7)N8C=NC9=C(N=CN=C98)N)O)O)O)N	IC50 ~ 50000 nM	Poor binder
T25200	Ribonuclease L	B9NQ6D	N-[1-[(4-Acetylphenyl)carbamothioylamino]-2,2,2-trichloroethyl]-2-phenylacetamide	Investigative	2887364	C19H18Cl3N3O2S	458.8	CC(=O)C1=CC=C(C=C1)NC(=S)NC(C(Cl)(Cl)Cl)NC(=O)CC2=CC=CC=C2	EC50 = 79000 nM	Poor binder
T25200	Ribonuclease L	BC20FG	2-[(3-Chloro-2-methylphenyl)imino]-5-(4-nitrobenzylidene)-1,3-thiazolidin-4-one	Investigative	135438932	C17H12ClN3O3S	373.8	CC1=C(C=CC=C1Cl)N=C2NC(=O)/C(=C/C3=CC=C(C=C3)[N+](=O)[O-])/S2	EC50 = 50000 nM	Poor binder
T25200	Ribonuclease L	BOF7E4	Butyl 4-[[2,2,2-trichloro-1-(propanoylamino)ethyl]carbamothioylamino]benzoate	Investigative	24810890	C17H22Cl3N3O3S	454.8	CCCCOC(=O)C1=CC=C(C=C1)NC(=S)NC(C(Cl)(Cl)Cl)NC(=O)CC	EC50 = 90000 nM	Poor binder
T25200	Ribonuclease L	BZS9L2	[(2R,3R,4R,5S)-5-(6-Aminopurin-9-yl)-4-[[(2R,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methyl [(2S,3R,4S,5R)-2-(6-aminopurin-9-yl)-4-hydroxy-5-phosphonooxyoxolan-3-yl] hydrogen phosphate	Investigative	46875164	C29H36N15O19P3	991.6	C1=NC(=C2C(=N1)N(C=N2)[C@@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O[C@@H]4[C@@H]([C@H](O[C@@H]4N5C=NC6=C(N=CN=C65)N)OP(=O)(O)O)O)O)OP(=O)(O)OC[C@@H]7[C@H]([C@H](C(O7)N8C=NC9=C(N=CN=C98)N)O)O)N	IC50 ~ 50000 nM	Poor binder