TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T25608	Free fatty acid receptor 1	B08HYR	Chembl4242595	Investigative	145984009	C23H24F2O5	418.4	COC1CC(C1)OC2=CC(=C(C(=C2)F)F)C3=CC4=C(C=C3)O[C@H](CC4)CCC(=O)O	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B0VMY3	({5-[(1-Naphthylmethyl)sulfanyl]-1,3,4-thiadiazol-2-yl}sulfanyl)acetic acid	Investigative	853224	C15H12N2O2S3	348.5	C1=CC=C2C(=C1)C=CC=C2CSC3=NN=C(S3)SCC(=O)O	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B1JYW0	(3S)-3-(1-Methylimidazol-2-yl)-3-[4-[[3-[2-(trifluoromethoxy)phenyl]phenyl]methoxy]phenyl]propanoic acid	Investigative	127036748	C27H23F3N2O4	496.5	CN1C=CN=C1[C@@H](CC(=O)O)C2=CC=C(C=C2)OCC3=CC(=CC=C3)C4=CC=CC=C4OC(F)(F)F	EC50 = 61000 nM	Poor binder
T25608	Free fatty acid receptor 1	B1QK4C	10-Hydroxylauric acid	Investigative	10176767	C12H24O3	216.32	CCC(CCCCCCCCC(=O)O)O	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B26CVM	4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide	Investigative	743974	C16H19NO3S	305.4	CC1=CC(=C(C(=C1)C)NS(=O)(=O)C2=CC=C(C=C2)OC)C	EC50 ~ 50118.72 nM	Poor binder
T25608	Free fatty acid receptor 1	B2BZ0A	11-Hydroxylauric acid	Investigative	169433	C12H24O3	216.32	CC(CCCCCCCCCC(=O)O)O	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B2ZY1V	Chembl4239630	Investigative	145985219	C23H26F2O5	420.4	CC1=CC(=CC(=C1OCCCC(=O)O)C)C2=C(C(=CC(=C2)OC3CC(C3)OC)F)F	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B32UKZ	2-(3-Fluoro-5-pyridin-2-yloxyphenyl)-3H-1,2-benzothiazole 1,1-dioxide	Investigative	86280676	C18H13FN2O3S	356.4	C1C2=CC=CC=C2S(=O)(=O)N1C3=CC(=CC(=C3)F)OC4=CC=CC=N4	IC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B3G8PM	Chembl4292184	Investigative	145986478	C26H27NO7	465.5	CC#C[C@@H](CC(=O)O)C1=CC=C(C=C1)OC[C@H]2COC3=C(O2)C=C(C=C3)C(=O)N4CCOCC4	EC50 ~ 50000 nM	Poor binder
T25608	Free fatty acid receptor 1	B3P6IW	Chembl4246396	Investigative	145984796	C21H20F4O5	428.4	COC1CC(C1)OC2=CC(=C(C(=C2)F)F)C3=CC(=C(C(=C3)F)OCCCC(=O)O)F	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B41PAO	3-[4-[[3-(Furan-2-yl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid	Investigative	75511305	C16H14N2O5	314.29	C1=COC(=C1)C2=NOC(=N2)COC3=CC=C(C=C3)CCC(=O)O	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B5M8PL	2-(3-Chloro-5-pyridin-2-yloxyphenyl)-3H-1,2-benzothiazole 1,1-dioxide	Investigative	134132711	C18H13ClN2O3S	372.8	C1C2=CC=CC=C2S(=O)(=O)N1C3=CC(=CC(=C3)Cl)OC4=CC=CC=N4	IC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B7CRB8	(3S)-3-(1-Methylimidazol-2-yl)-3-[4-[[3-(2-methylphenyl)phenyl]methoxy]phenyl]propanoic acid	Investigative	127037608	C27H26N2O3	426.5	CC1=CC=CC=C1C2=CC=CC(=C2)COC3=CC=C(C=C3)[C@H](CC(=O)O)C4=NC=CN4C	EC50 = 89000 nM	Poor binder
T25608	Free fatty acid receptor 1	B7DPK4	2-(3-Fluoro-5-pyridin-3-yloxyphenyl)-3H-1,2-benzothiazole 1,1-dioxide	Investigative	46892131	C18H13FN2O3S	356.4	C1C2=CC=CC=C2S(=O)(=O)N1C3=CC(=CC(=C3)F)OC4=CN=CC=C4	IC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B89MUR	Chembl4250664	Investigative	145984594	C22H22F2O7	436.4	COC1CC(C1)OC2=CC(=C3C(=C2)OCO3)C4=CC(=C(C(=C4)F)OCCCC(=O)O)F	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B8W9RN	2-[3-(1,1-Dioxo-3H-1,2-benzothiazol-2-yl)-5-fluorophenoxy]benzonitrile	Investigative	134145071	C20H13FN2O3S	380.4	C1C2=CC=CC=C2S(=O)(=O)N1C3=CC(=CC(=C3)F)OC4=CC=CC=C4C#N	IC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	B9C1EM	2-(3-Fluoro-5-pyridin-4-yloxyphenyl)-3H-1,2-benzothiazole 1,1-dioxide	Investigative	134153222	C18H13FN2O3S	356.4	C1C2=CC=CC=C2S(=O)(=O)N1C3=CC(=CC(=C3)F)OC4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BBXY56	Chembl4239572	Investigative	145984445	C23H24F4O5	456.4	CC(C)(CCOC1=C(C=C(C=C1F)C2=C(C(=CC(=C2)OC3CC(C3)OC)F)F)F)C(=O)O	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BF25WK	4-Methyl-N-(9H-xanthen-9-yl)benzenesulfonamide	Investigative	233085	C20H17NO3S	351.4	CC1=CC=C(C=C1)S(=O)(=O)NC2C3=CC=CC=C3OC4=CC=CC=C24	EC50 ~ 50118.72 nM	Poor binder
T25608	Free fatty acid receptor 1	BG5Q9S	2-(3-Pyridin-2-yloxyphenyl)-3H-1,2-benzothiazole 1,1-dioxide	Investigative	134133797	C18H14N2O3S	338.4	C1C2=CC=CC=C2S(=O)(=O)N1C3=CC(=CC=C3)OC4=CC=CC=N4	IC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BG7T5M	9-Hydroxy-dodecanoic acid	Investigative	5312744	C12H24O3	216.32	CCCC(CCCCCCCC(=O)O)O	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BG8RK7	7-Hydroxylauric acid	Investigative	5312743	C12H24O3	216.32	CCCCCC(CCCCCC(=O)O)O	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BLCO70	(3S)-3-[4-[[3-(2-Ethylphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid	Investigative	127035668	C28H28N2O3	440.5	CCC1=CC=CC=C1C2=CC=CC(=C2)COC3=CC=C(C=C3)[C@H](CC(=O)O)C4=NC=CN4C	EC50 = 65000 nM	Poor binder
T25608	Free fatty acid receptor 1	BLT36V	5-Hydroxydodecaneoic acid sodium salt	Investigative	102338889	C12H23NaO3	238.3	CCCCCCCC(CCCC(=O)[O-])O.[Na+]	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BNUC80	(3S)-3-[4-[[3-(2-Chlorophenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid	Investigative	127035667	C26H23ClN2O3	446.9	CN1C=CN=C1[C@@H](CC(=O)O)C2=CC=C(C=C2)OCC3=CC(=CC=C3)C4=CC=CC=C4Cl	EC50 = 56000 nM	Poor binder
T25608	Free fatty acid receptor 1	BO2Y4J	Chembl4248845	Investigative	145986262	C21H20F4O5	428.4	C1COCCC1OC2=CC(=C(C(=C2)F)F)C3=CC(=C(C(=C3)F)OCCCC(=O)O)F	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BT5B7U	Chembl4240607	Investigative	145983493	C22H22F4O5	442.4	COC1CC(C1)OC2=CC(=C(C(=C2)F)F)C3=CC(=C(C(=C3)F)OCCCCC(=O)O)F	EC50 = 68780 nM	Poor binder
T25608	Free fatty acid receptor 1	BTGX86	3-(4-Ethynylphenyl)propanoic acid	Investigative	54757519	C11H10O2	174.2	C#CC1=CC=C(C=C1)CCC(=O)O	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BV24QH	Chembl4243863	Investigative	145985748	C21H20F4O4S	444.4	COC1CC(C1)OC2=CC(=C(C(=C2)F)F)C3=CC(=C(C(=C3)F)SCCCC(=O)O)F	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BVN2Q6	Sodium 4-hydroxydodecanoate	Investigative	23699039	C12H23NaO3	238.3	CCCCCCCCC(CCC(=O)[O-])O.[Na+]	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BX8B0O	Chembl4246850	Investigative	87055315	C19H21F2NO3	349.4	CC(C)NC1=CC=CC=C1C2=CC(=C(C(=C2)F)OCCCC(=O)O)F	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	BY4S8L	3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic-2,2-d2 acid	Investigative	145967778	C23H21FO3	366.4	[2H]C([2H])(CC1=CC=C(C=C1)OCC2=C(C=CC(=C2)F)C3=CC=C(C=C3)C)C(=O)O	EC50 = 75900 nM	Poor binder
T25608	Free fatty acid receptor 1	BY6KI8	8-Hydroxydodecanoic acid	Investigative	14454530	C12H24O3	216.32	CCCCC(CCCCCCC(=O)O)O	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	D03JPL	12-hydroxylauric acid	Investigative	79034	C12H24O3	216.32	C(CCCCCC(=O)O)CCCCCO	EC50 ~ 100000 nM	Poor binder
T25608	Free fatty acid receptor 1	D0K6EG	TUG-891	Investigative	57522038	C23H21FO3	364.4	CC1=CC=C(C=C1)C2=C(C=C(C=C2)F)COC3=CC=C(C=C3)CCC(=O)O	EC50 = 52600 nM	Poor binder
T25608	Free fatty acid receptor 1	D0T2CG	3-hydroxylauric acid	Investigative	94216	C12H24O3	216.32	CCCCCCCCCC(CC(=O)O)O	EC50 ~ 100000 nM	Poor binder