TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T25956	Histone acetyltransferase p300	B06GPV	5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole	Investigative	72201043	C6H4N2S4	232.4	C1=C(SN=C1)SSC2=CC=NS2	IC50 = 58000 nM	Poor binder
T25956	Histone acetyltransferase p300	B0XF6S	4-Methoxynaphthalen-1-amine hydrochloride	Investigative	18783165	C11H12ClNO	209.67	COC1=CC=C(C2=CC=CC=C21)N.Cl	IC50 = 95000 nM	Poor binder
T25956	Histone acetyltransferase p300	B1PWK3	Chembl4289431	Investigative	145987968	C11H9N3O2S	247.28	CN1C(=O)/C(=C/C2=CC=NC=C2)/C(=O)NC1=S	IC50 ~ 50000 nM	Poor binder
T25956	Histone acetyltransferase p300	B2I1QU	6-Hydroxy-5-[(Z)-indol-3-ylidenemethyl]-1-methyl-2-sulfanylidenepyrimidin-4-one	Investigative	135457159	C14H11N3O2S	285.32	CN1C(=C(C(=O)NC1=S)/C=C/2\\C=NC3=CC=CC=C32)O	IC50 ~ 50000 nM	Poor binder
T25956	Histone acetyltransferase p300	B3DM8C	6-[(5Z)-5-[1-[(4-Nitrophenyl)methyl]-2-oxoindol-3-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoic acid	Investigative	90667752	C24H21N3O6S2	511.6	C1=CC=C2C(=C1)/C(=C/3\\C(=O)N(C(=S)S3)CCCCCC(=O)O)/C(=O)N2CC4=CC=C(C=C4)[N+](=O)[O-]	IC50 = 151900 nM	Poor binder
T25956	Histone acetyltransferase p300	B4BJZ3	6-[(5Z)-5-[1-[(4-Methoxyphenyl)methyl]-2-oxoindol-3-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoic acid	Investigative	90667751	C25H24N2O5S2	496.6	COC1=CC=C(C=C1)CN2C3=CC=CC=C3/C(=C/4\\C(=O)N(C(=S)S4)CCCCCC(=O)O)/C2=O	IC50 = 61900 nM	Poor binder
T25956	Histone acetyltransferase p300	B62SRF	2,6-Bis(3-carboxy-4-hydroxybenzylidene)cyclohexanone	Investigative	16203604	C22H18O7	394.4	C1C/C(=C\\C2=CC(=C(C=C2)O)C(=O)O)/C(=O)/C(=C/C3=CC(=C(C=C3)O)C(=O)O)/C1	IC50 = 168000 nM	Poor binder
T25956	Histone acetyltransferase p300	B7J6WO	6-{(5Z)-5-[1-(4-Methylbenzyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}hexanoic acid	Investigative	1561807	C25H24N2O4S2	480.6	CC1=CC=C(C=C1)CN2C3=CC=CC=C3/C(=C/4\\C(=O)N(C(=S)S4)CCCCCC(=O)O)/C2=O	IC50 = 81000 nM	Poor binder
T25956	Histone acetyltransferase p300	BCU01K	[(3,5-Dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)amino] 4-methoxybenzenesulfonate	Investigative	2221149	C15H15NO5S	321.3	CC1=CC(=NOS(=O)(=O)C2=CC=C(C=C2)OC)C=C(C1=O)C	IC50 = 128000 nM	Poor binder
T25956	Histone acetyltransferase p300	BCXJ90	Chembl4170165	Investigative	145954899	C11H11NO2	189.21	COC1=C(C2=CC=CC=C2C(=C1)O)N	IC50 = 52000 nM	Poor binder
T25956	Histone acetyltransferase p300	BFK06R	8-[(5Z)-5-[1-[(4-Methylphenyl)methyl]-2-oxoindol-3-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]octanoic acid	Investigative	90667754	C27H28N2O4S2	508.7	CC1=CC=C(C=C1)CN2C3=CC=CC=C3/C(=C/4\\C(=O)N(C(=S)S4)CCCCCCCC(=O)O)/C2=O	IC50 = 95300 nM	Poor binder
T25956	Histone acetyltransferase p300	BGSB68	(5E)-1-Methyl-5-{[5-(morpholin-4-yl)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione	Investigative	7333990	C14H15N3O4S	321.35	CN1C(=O)/C(=C/C2=CC=C(O2)N3CCOCC3)/C(=O)NC1=S	IC50 ~ 50000 nM	Poor binder
T25956	Histone acetyltransferase p300	BK3PE9	Chembl4299337	Investigative	145948689	C116H205N42O45P3S	3033.1	C[C@@H]([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@H](C)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)NC)NC(=O)CNC(=O)CNC(=O)N[C@H](CCCCNC(=O)CSCCNC(=O)CCNC(=O)[C@H](C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]1[C@@H]([C@@H]([C@H](O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O)C(=O)N[C@@H](C)C(=O)N4CCC[C@@H]4C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)O)O	IC50 = 200000 nM	Poor binder
T25956	Histone acetyltransferase p300	BL9I7P	Chembl4170179	Investigative	145955588	C20H27NO2	313.4	CCCCCCCCCC(=O)NC1=CC=C(C2=CC=CC=C21)O	IC50 = 60000 nM	Poor binder
T25956	Histone acetyltransferase p300	BR8IH7	2-[4-[2-[3-(3,4-Dimethoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-1,3-thiazol-4-yl]phenyl]isoindole-1,3-dione	Investigative	2854538	C32H24N4O4S2	592.7	COC1=C(C=C(C=C1)C2CC(=NN2C3=NC(=CS3)C4=CC=C(C=C4)N5C(=O)C6=CC=CC=C6C5=O)C7=CC=CS7)OC	IC50 = 150000 nM	Poor binder
T25956	Histone acetyltransferase p300	BX1FQ9	Cyqualon	Investigative	1550234	C22H22O5	366.4	COC1=C(C=CC(=C1)/C=C\\2/C(=O)/C(=C/C3=CC(=C(C=C3)O)OC)/CCC2)O	IC50 = 111000 nM	Poor binder
T25956	Histone acetyltransferase p300	BYRC03	4-Nitro-1-naphthol	Investigative	343829	C10H7NO3	189.17	C1=CC=C2C(=C1)C(=CC=C2O)[N+](=O)[O-]	IC50 = 106000 nM	Poor binder
T25956	Histone acetyltransferase p300	D09AFM	AMI-1	Investigative	67254	C21H16N2O9S2	504.5	C1=CC2=C(C=C(C=C2C=C1NC(=O)NC3=CC4=CC(=CC(=C4C=C3)O)S(=O)(=O)O)S(=O)(=O)O)O	IC50 = 118500 nM	Poor binder
T25956	Histone acetyltransferase p300	D0YL8Z	C646	Investigative	1285941	C24H19N3O6	445.4	CC1=CC(=C(C=C1C)[N+](=O)[O-])C2=CC=C(O2)/C=C\\3/C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C	IC50 = 51000 nM	Poor binder