TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T27889 Angiotensin-converting enzyme 2 B04REJ (E)-3-[5-(5-Chloro-2-methylphenyl)furan-2-yl]-2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]prop-2-enoic acid Investigative 1382255 C17H14ClN3O3S 375.8 CC1=C(C=C(C=C1)Cl)C2=CC=C(O2)/C=C(\\C(=O)O)/SC3=NNC(=N3)C IC50 = 62000 nM Poor binder T27889 Angiotensin-converting enzyme 2 BD2V9Y N-(Carboxymethyl)-N-(3-Phenylpropyl)glycyl-N-Methyl-L-Histidinamide Investigative 54589400 C20H27N5O4 401.5 CNC(=O)[C@H](CC1=CN=CN1)NC(=O)CN(CCCC2=CC=CC=C2)CC(=O)O IC50 ~ 100000 nM Poor binder T27889 Angiotensin-converting enzyme 2 BFQ98Z N-(2-Aminoethyl)-1-aziridineethanamine Investigative 98888 C6H15N3 129.199 C1CN1CCNCCN IC50 = 57000 nM Poor binder