TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T31543	Suppressor of tumorigenicity 14 protein	B2QF5H	2-(2-Hydroxyphenyl)-1H-indole-5-carboximidamide	Investigative	1508	C15H13N3O	251.28	C1=CC=C(C(=C1)C2=CC3=C(N2)C=CC(=C3)C(=N)N)O	Ki = 60000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	B56NTY	(Z)-2-Cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-(4-hydroxyphenyl)prop-2-enamide	Investigative	869194	C18H16N2O4	324.3	CCOC1=C(C=CC(=C1)/C=C(/C#N)\\C(=O)NC2=CC=C(C=C2)O)O	IC50 = 98000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	B6BG3L	(E)-3-[3-[(4-Chlorophenoxy)methyl]-4-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one	Investigative	5729350	C23H19ClO4	394.8	COC1=C(C=C(C=C1)/C=C/C(=O)C2=CC=C(C=C2)O)COC3=CC=C(C=C3)Cl	IC50 = 138000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	B8HRY5	(2Z)-2-Benzimidazol-2-yl-3-[3-methoxy-4-(2-morpholin-4-yl-2-oxoethoxy)phenyl]p rop-2-enenitrile	Investigative	5739522	C23H22N4O4	418.4	COC1=C(C=CC(=C1)/C=C(/C#N)\\C2=NC3=CC=CC=C3N2)OCC(=O)N4CCOCC4	IC50 = 128000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	B9OK7V	2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43R,49S)-25-(4-Aminobutyl)-49-benzyl-4,19-bis[(2S)-butan-2-yl]-34-[[4-(diaminomethylideneamino)phenyl]methyl]-28-[(1R)-1-hydroxyethyl]-22-(hydroxymethyl)-3,6,12,18,21,24,27,30,33,36,39,42,48,51-tetradecaoxo-53,54-dithia-2,5,11,17,20,23,26,29,32,35,38,41,47,50-tetradecazapentacyclo[29.20.4.07,11.013,17.043,47]pentapentacontan-40-yl]acetic acid	Investigative	44436352	C71H104N18O18S2	1561.8	CC[C@H](C)[C@H]1C(=O)N[C@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)N4CCC[C@H]4C(=O)N1)[C@@H](C)CC)CO)CCCCN)[C@@H](C)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H]5CCCN5C(=O)[C@@H](NC2=O)CC6=CC=CC=C6)CC(=O)O)CC7=CC=C(C=C7)N=C(N)N	Ki = 90000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	BDIY94	(Z)-2-Cyano-3-(4-hydroxy-3-methoxyphenyl)-N-(4-methoxyphenyl)prop-2-enamide	Investigative	2262135	C18H16N2O4	324.3	COC1=CC=C(C=C1)NC(=O)/C(=C\\C2=CC(=C(C=C2)O)OC)/C#N	IC50 = 120000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	BHAG94	(7R,10S,13S,21S,24S,27S,30S,33S,36S,39S,42S,45R)-7-Acetamido-36-(3-amino-3-oxopropyl)-13-benzyl-24-(4-carbamimidamidobutyl)-39-(carboxymethyl)-10-(hydroxymethyl)-21-[(4-hydroxyphenyl)methyl]-33-(1H-imidazol-5-ylmethyl)-30-methyl-42-(2-methylpropyl)-8,11,14,19,22,25,28,34,37,40,43-undecaoxo-5,47,52-trithia-9,12,15,20,23,26,29,32,35,38,41,44-dodecazatetracyclo[25.23.3.13,49.015,18]tetrapentaconta-1,3(54),49-triene-45-carboxylic acid	Investigative	137654508	C76H105N19O19S3	1685	C[C@H]1CN[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSCC2=CC3=CC(=C2)CSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4CCC4C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](CSC3)C(=O)N1)CCCCNC(=N)N)CC5=CC=C(C=C5)O)CC6=CC=CC=C6)CO)NC(=O)C)C(=O)O)CC(C)C)CC(=O)O)CCC(=O)N)CC7=CN=CN7	Ki = 50000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	BIL7N8	(2Z)-2-Cyano-3-(4-hydroxy-3-methoxyphenyl)-N-(4-hydroxyphenyl)prop-2-enamide	Investigative	725447	C17H14N2O4	310.3	COC1=C(C=CC(=C1)/C=C(/C#N)\\C(=O)NC2=CC=C(C=C2)O)O	IC50 = 111000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	BJQ0O8	2-(4-{(1Z)-2-Cyano-2-[N-(3-ethoxyphenyl)carbamoyl]vinyl}-2-methoxyphenoxy)acet ic acid	Investigative	2208579	C21H20N2O6	396.4	CCOC1=CC=CC(=C1)NC(=O)/C(=C\\C2=CC(=C(C=C2)OCC(=O)O)OC)/C#N	IC50 = 75000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	BN9O6A	(5E)-5-(3,4-Dimethoxybenzylidene)-3-{[(5-fluoro-2-methylphenyl)amino]methyl}-1,3-thiazolidine-2,4-dione	Investigative	2262990	C20H19FN2O4S	402.4	CC1=C(C=C(C=C1)F)NCN2C(=O)/C(=C\\C3=CC(=C(C=C3)OC)OC)/SC2=O	IC50 = 103000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	BUVP68	Chembl4162159	Investigative	145959466	C63H96N18O18S2	1457.7	CC[C@H](C)[C@H]1C(=O)N[C@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N3CCC[C@H]3C(=O)N4CCC[C@H]4C(=O)N1)CO)CCCCN)[C@@H](C)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H]5CCCN5C(=O)[C@@H](NC2=O)CC6=CC=CC=C6)CC(=O)O)CCCN=C(N)N	IC50 ~ 50000 nM	Poor binder
T31543	Suppressor of tumorigenicity 14 protein	BXM7L4	2-[(1S,7S,10S,13S,16S,22R,25S,31S,34S,37S,40S,43S,46S)-40-(4-Aminobutyl)-16-benzyl-10,46-bis[(2S)-butan-2-yl]-31-[3-(diaminomethylideneamino)propyl]-37-[(1R)-1-hydroxyethyl]-13,34,43-tris(hydroxymethyl)-2,8,11,14,17,23,26,29,32,35,38,41,44,47-tetradecaoxo-3,9,12,15,18,24,27,30,33,36,39,42,45,48-tetradecazatetracyclo[46.3.0.03,7.018,22]henpentacontan-25-yl]acetic acid	Investigative	44436356	C67H106N18O20	1483.7	CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N2CCC[C@@H]2C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)N4CCC[C@H]4C(=O)N1)[C@@H](C)CC)CO)CCCCN)[C@@H](C)O)CO)CCCN=C(N)N)CC(=O)O)CC5=CC=CC=C5)CO	Ki = 107000 nM	Poor binder