TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T31902	Mammalian disintegrin-metalloprotease	B0KPS2	(5S)-4-(1-Adamantylmethyl)-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]-5-[(4-hydroxyphenyl)methyl]piperazine-2,3-dione	Investigative	122181847	C43H57N5O6	739.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@H](CC3=CC=C(C=C3)O)N4C[C@@H](N(C(=O)C4=O)CC56CC7CC(C5)CC(C7)C6)CC8=CC=C(C=C8)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	B1L0CN	(5S)-4-(Cyclobutylmethyl)-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]-5-[(4-hydroxyphenyl)methyl]piperazine-2,3-dione	Investigative	122181849	C37H49N5O6	659.8	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@H](CC3=CC=C(C=C3)O)N4C[C@@H](N(C(=O)C4=O)CC5CCC5)CC6=CC=C(C=C6)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	B2F1XY	(5R)-4-[2-(1-Adamantyl)ethyl]-5-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione	Investigative	122181993	C52H61N5O6	852.1	C1C[C@H](N(C1)C[C@H](CC2=CC=C(C=C2)O)N3C[C@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC=C(C=C7)O)CN8[C@@H](CNC(=O)C8=O)CC9=CC1=CC=CC=C1C=C9	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	B30EOS	(5S)-4-[2-(1-Adamantyl)ethyl]-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]-5-(naphthalen-2-ylmethyl)piperazine-2,3-dione	Investigative	122181989	C48H61N5O5	788	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@H](CC3=CC=C(C=C3)O)N4C[C@@H](N(C(=O)C4=O)CCC56CC7CC(C5)CC(C7)C6)CC8=CC9=CC=CC=C9C=C8	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	B4KP2H	Grassystatin B	Investigative	44253976	C59H97N9O16	1188.5	CC[C@@H](C(=O)N(C)[C@H](CC1=CC=CC=C1)C(=O)N2CCC[C@H]2C(=O)OC)NC(=O)[C@H]([C@@H](C)O)NC(=O)C[C@@H]([C@H](CC(C)C)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C(C)C)OC(=O)[C@H](C(C)C)OC(=O)[C@H](C(C)C)N(C)C)O	IC50 = 87200 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	B52MUV	(5S)-4-[2-(1-Adamantyl)ethyl]-5-butyl-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione	Investigative	122181996	C49H63N5O5	802.1	CCCC[C@H]1CN(C(=O)C(=O)N1CCC23CC4CC(C2)CC(C4)C3)[C@@H](CC5=CC=C(C=C5)O)CN6CCC[C@H]6CN7[C@@H](CNC(=O)C7=O)CC8=CC9=CC=CC=C9C=C8	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	B7QJE6	Schembl21751149	Investigative	78426757	C48H59N5O5	786	C1C[C@H](N(C1)C[C@H](CC2=CC=CC=C2)N3C[C@@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC=C(C=C7)O)CN8[C@H](CNC(=O)C8=O)CC9=CC=CC=C9	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	B8ZA1E	(5R)-4-[2-(1-Adamantyl)ethyl]-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]-5-(naphthalen-2-ylmethyl)piperazine-2,3-dione	Investigative	122181990	C48H61N5O5	788	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@H](CC3=CC=C(C=C3)O)N4C[C@H](N(C(=O)C4=O)CCC56CC7CC(C5)CC(C7)C6)CC8=CC9=CC=CC=C9C=C8	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	B9BDK4	(5S)-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-Dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]-5-[(4-hydroxyphenyl)methyl]-4-(2-phenylbutyl)piperazine-2,3-dione	Investigative	122181850	C42H53N5O6	723.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@H](CC3=CC=C(C=C3)O)N4C[C@@H](N(C(=O)C4=O)CC(CC)C5=CC=CC=C5)CC6=CC=C(C=C6)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	B9CYO6	(5R)-4-[2-(1-Adamantyl)ethyl]-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]-5-[(4-hydroxyphenyl)methyl]piperazine-2,3-dione	Investigative	122181988	C44H59N5O6	754	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@H](CC3=CC=C(C=C3)O)N4C[C@H](N(C(=O)C4=O)CCC56CC7CC(C5)CC(C7)C6)CC8=CC=C(C=C8)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BB5SG2	(5S)-4-[2-(1-Adamantyl)ethyl]-5-[(4-hydroxyphenyl)methyl]-1-[(2R)-1-[(2S)-2-[[(6R)-6-[(4-hydroxyphenyl)methyl]-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-naphthalen-2-ylpropan-2-yl]piperazine-2,3-dione	Investigative	122181997	C52H61N5O6	852.1	C1C[C@H](N(C1)C[C@@H](CC2=CC3=CC=CC=C3C=C2)N4C[C@@H](N(C(=O)C4=O)CCC56CC7CC(C5)CC(C7)C6)CC8=CC=C(C=C8)O)CN9[C@@H](CNC(=O)C9=O)CC1=CC=C(C=C1)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BBY7O2	(5S)-4-[2-(1-Adamantyl)ethyl]-5-butyl-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]piperazine-2,3-dione	Investigative	122181991	C41H61N5O5	704	CCCC[C@H]1CN(C(=O)C(=O)N1CCC23CC4CC(C2)CC(C4)C3)[C@@H](CC5=CC=C(C=C5)O)CN6CCC[C@H]6CN7[C@H](CNC(=O)C7=O)CCC	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BC6T0Q	(5S)-5-Benzyl-1-[(2R)-1-[(2S)-2-[[(6R)-6-benzyl-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-cyclohexylpropan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181999	C44H55N5O4	717.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=CC=C7	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BH1N4I	(5R)-4-[2-(1-Adamantyl)ethyl]-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-5-(naphthalen-2-ylmethyl)piperazine-2,3-dione	Investigative	122181995	C56H63N5O5	886.1	C1C[C@H](N(C1)C[C@H](CC2=CC=C(C=C2)O)N3C[C@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC8=CC=CC=C8C=C7)CN9[C@@H](CNC(=O)C9=O)CC1=CC2=CC=CC=C2C=C1	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BIBX94	CID 78426619	Investigative	78426619	C44H55N5O5	733.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=C(C=C7)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BJ1LV0	(5S)-5-Benzyl-1-[(2R)-1-cyclohexyl-3-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181998	C40H55N5O4	669.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@@H](CC3CCCCC3)N4C[C@@H](N(C(=O)C4=O)CCC5=CC=CC=C5)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BK9N5U	Grassystatin C	Investigative	44253975	C50H82N8O12	987.2	CC[C@H](C)[C@@H](C(=O)NCC(=O)N(C)[C@H](CC1=CC=CC=C1)C(=O)N2CCC[C@H]2C(=O)OC)NC(=O)C[C@@H]([C@H](CC(C)C)NC(=O)[C@H](CCC(=O)N)N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@@H]([C@@H](C)CC)O)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BMT27D	(5S)-4-[2-(1-Adamantyl)ethyl]-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]-5-[(4-hydroxyphenyl)methyl]piperazine-2,3-dione	Investigative	122181851	C44H59N5O6	754	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@H](CC3=CC=C(C=C3)O)N4C[C@@H](N(C(=O)C4=O)CCC56CC7CC(C5)CC(C7)C6)CC8=CC=C(C=C8)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BSK12E	(5S)-4-[2-(1-Adamantyl)ethyl]-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-5-(naphthalen-2-ylmethyl)piperazine-2,3-dione	Investigative	122181994	C56H63N5O5	886.1	C1C[C@H](N(C1)C[C@H](CC2=CC=C(C=C2)O)N3C[C@@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC8=CC=CC=C8C=C7)CN9[C@@H](CNC(=O)C9=O)CC1=CC2=CC=CC=C2C=C1	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BTH54D	(5S)-4-[2-(1-Adamantyl)ethyl]-5-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione	Investigative	122181992	C52H61N5O6	852.1	C1C[C@H](N(C1)C[C@H](CC2=CC=C(C=C2)O)N3C[C@@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC=C(C=C7)O)CN8[C@@H](CNC(=O)C8=O)CC9=CC1=CC=CC=C1C=C9	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BWXS48	(5S)-4-[(4-Tert-butylcyclohexyl)methyl]-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]-5-[(4-hydroxyphenyl)methyl]piperazine-2,3-dione	Investigative	122181846	C43H61N5O6	744	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@H](CC3=CC=C(C=C3)O)N4C[C@@H](N(C(=O)C4=O)CC5CCC(CC5)C(C)(C)C)CC6=CC=C(C=C6)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BXKU70	(5S)-4-(Cyclopentylmethyl)-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]-5-[(4-hydroxyphenyl)methyl]piperazine-2,3-dione	Investigative	122181852	C38H51N5O6	673.8	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@H](CC3=CC=C(C=C3)O)N4C[C@@H](N(C(=O)C4=O)CC5CCCC5)CC6=CC=C(C=C6)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	BZ0W9C	(5S)-4-(Cyclohexylmethyl)-1-[(2S)-1-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)propan-2-yl]-5-[(4-hydroxyphenyl)methyl]piperazine-2,3-dione	Investigative	122181848	C39H53N5O6	687.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@H](CC3=CC=C(C=C3)O)N4C[C@@H](N(C(=O)C4=O)CC5CCCCC5)CC6=CC=C(C=C6)O	IC50 ~ 100000 nM	Poor binder
T31902	Mammalian disintegrin-metalloprotease	D0Y5IQ	GRASSYSTATIN A	Investigative	44255320	C58H95N9O16	1174.4	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N(C)[C@H](CC1=CC=CC=C1)C(=O)N2CCC[C@H]2C(=O)OC)NC(=O)C[C@@H]([C@H](CC(C)C)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C(C)C)OC(=O)[C@H](C(C)C)OC(=O)[C@H](C(C)C)N(C)C)O)O	IC50 ~ 100000 nM	Poor binder