TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T32972	Lanosterol 14-alpha demethylase	D02NTO	Tolnaftate	Approved	5510	C19H17NOS	307.4	CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2	IC50 = 50000 nM	Poor binder
T32972	Lanosterol 14-alpha demethylase	D06XMU	Testosterone	Approved	6013	C19H28O2	288.4	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=O)CC[C@]34C	IC50 = 50000 nM	Poor binder
T32972	Lanosterol 14-alpha demethylase	D0C1SF	Griseofulvin	Approved	441140	C17H17ClO6	352.8	C[C@@H]1CC(=O)C=C([C@]12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC	IC50 = 50000 nM	Poor binder
T32972	Lanosterol 14-alpha demethylase	B6DMZ4	5-Chloro-N-[(2R)-1-(4-hydroxypiperidin-1-yl)-1-oxo-3-phenylpropan-2-yl]-1H-indole-2-carboxamide	Investigative	44450780	C23H24ClN3O3	425.9	C1CN(CCC1O)C(=O)[C@@H](CC2=CC=CC=C2)NC(=O)C3=CC4=C(N3)C=CC(=C4)Cl	IC50 = 100000 nM	Poor binder
T32972	Lanosterol 14-alpha demethylase	BP2V6O	5-Fluoro-N-[(2S)-1-(4-hydroxypiperidin-1-yl)-1-oxo-3-phenylpropan-2-yl]-1H-indole-2-carboxamide	Investigative	44450787	C23H24FN3O3	409.5	C1CN(CCC1O)C(=O)[C@H](CC2=CC=CC=C2)NC(=O)C3=CC4=C(N3)C=CC(=C4)F	IC50 = 75000 nM	Poor binder
T32972	Lanosterol 14-alpha demethylase	BTUR20	5-Chloro-N-[1-(4-hydroxypiperidine-1-carbonyl)cyclopentyl]-1H-indole-2-carboxamide	Investigative	44450782	C20H24ClN3O3	389.9	C1CCC(C1)(C(=O)N2CCC(CC2)O)NC(=O)C3=CC4=C(N3)C=CC(=C4)Cl	IC50 = 100000 nM	Poor binder