TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T33901	Niemann-Pick C1-like protein 1	B37NRH	4-Fluoro-N-[(2R,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]benzamide	Investigative	118729153	C22H16F2N2O3	394.4	C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)NC(=O)C4=CC=C(C=C4)F)O	IC50 = 54000 nM	Poor binder
T33901	Niemann-Pick C1-like protein 1	B3V6IK	Tert-butyl(2-(8-(4-tert-butylbenzoyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)acetamido)methylcarbamate	Investigative	53324638	C32H43N5O5	577.7	CC(C)(C)C1=CC=C(C=C1)C(=O)N2CCC3(CC2)C(=O)N(CN3C4=CC=CC=C4)CC(=O)NCNC(=O)OC(C)(C)C	IC50 = 59000 nM	Poor binder
T33901	Niemann-Pick C1-like protein 1	BB9XA5	Benzyl 5-((1H-pyrazole-4-carboxamido)methyl)-2-(4-methylphenethyl)piperidine-1-carboxylate	Investigative	44574038	C27H32N4O3	460.6	CC1=CC=C(C=C1)CCC2CCC(CN2C(=O)OCC3=CC=CC=C3)CNC(=O)C4=CNN=C4	IC50 = 81000 nM	Poor binder
T33901	Niemann-Pick C1-like protein 1	BCK3M2	2-Phenylethyl 1-[(4-tert-butylbenzoyl)sulfamoyl]spiro[2H-indole-3,4'-piperidine]-1'-carboxylate	Investigative	44574016	C32H37N3O5S	575.7	CC(C)(C)C1=CC=C(C=C1)C(=O)NS(=O)(=O)N2CC3(CCN(CC3)C(=O)OCCC4=CC=CC=C4)C5=CC=CC=C52	IC50 = 79000 nM	Poor binder
T33901	Niemann-Pick C1-like protein 1	BKOD70	N-[(2R,3R)-1-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]-2-phenylacetamide	Investigative	118729152	C23H19FN2O3	390.4	C1=CC=C(C=C1)CC(=O)N[C@@H]2[C@H](N(C2=O)C3=CC=C(C=C3)F)C4=CC=C(C=C4)O	IC50 = 88000 nM	Poor binder
T33901	Niemann-Pick C1-like protein 1	BL1HN7	N-[(2R,3R)-1-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]benzamide	Investigative	118169537	C22H17FN2O3	376.4	C1=CC=C(C=C1)C(=O)N[C@@H]2[C@H](N(C2=O)C3=CC=C(C=C3)F)C4=CC=C(C=C4)O	IC50 = 70000 nM	Poor binder