TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T38529	Prostaglandin E2 receptor EP2	B2VGU9	2-[1-[2-(N-Benzoyl-4-methylanilino)ethyl]piperidin-4-yl]oxyacetic acid	Investigative	127029417	C23H28N2O4	396.5	CC1=CC=C(C=C1)N(CCN2CCC(CC2)OCC(=O)O)C(=O)C3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	B4BDZ3	(E)-3-[2-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]phenyl]-N-thiophen-2-ylsulfonylprop-2-enamide	Investigative	21362845	C30H21ClN2O3S2	557.1	C1=CC=C(C(=C1)/C=C/C(=O)NS(=O)(=O)C2=CC=CS2)C3=CC=CC(=C3)/C=C/C4=NC5=C(C=CC(=C5)Cl)C=C4	Ki = 70000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	B5L0OC	N-[4'-(6-Oxo-5,6,11,12-tetrahydrodibenzo[b,f]azocine-5-ylmethyl)-2-biphenylylsulfonyl]benzenepropanamide	Investigative	9938625	C37H32N2O4S	600.7	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)NC(=O)CCC6=CC=CC=C6	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	B5SGL4	7-[(2R)-2-[(E)-3-[3-(3-Chlorophenyl)phenyl]-3-hydroxyprop-1-enyl]-5-oxopyrrolidin-1-yl]heptanoic acid	Investigative	44290271	C26H30ClNO4	456	C1CC(=O)N([C@H]1/C=C/C(C2=CC=CC(=C2)C3=CC(=CC=C3)Cl)O)CCCCCCC(=O)O	Ki = 85000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	B61TJN	N-(2-Thienylsulfonyl)-3'-(methylsulfonyl)biphenyl-2-propionamide	Investigative	21362869	C20H19NO5S3	449.6	CS(=O)(=O)C1=CC=CC(=C1)C2=CC=CC=C2CCC(=O)NS(=O)(=O)C3=CC=CS3	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	B78WPV	7-[(2R)-2-[(E)-3-Hydroxy-3-[3-(4-hydroxy-2-methylphenyl)phenyl]prop-1-enyl]-5-oxopyrrolidin-1-yl]heptanoic acid	Investigative	44290257	C27H33NO5	451.6	CC1=C(C=CC(=C1)O)C2=CC(=CC=C2)C(/C=C/[C@H]3CCC(=O)N3CCCCCCC(=O)O)O	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	B8OW1G	5-[3-[(5R)-3,3-Difluoro-5-[(E,3R,4S)-3-hydroxy-4-methyl-9-phenylnon-1-enyl]-2-oxopyrrolidin-1-yl]propyl]thiophene-2-carboxylic acid	Investigative	90054392	C28H35F2NO4S	519.6	C[C@@H](CCCCCC1=CC=CC=C1)[C@H](/C=C/[C@H]2CC(C(=O)N2CCCC3=CC=C(S3)C(=O)O)(F)F)O	EC50 = 79000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	B92FAC	1-[2-[4-[(6-Oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(3-phenylpropyl)urea	Investigative	9960839	C38H35N3O4S	629.8	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)NC(=O)NCCCC6=CC=CC=C6	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BCPR29	7-[(R)-2-((E)-(S)-4-Cyclohexyl-3-hydroxy-but-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid	Investigative	44289921	C21H35NO4	365.5	C1CCC(CC1)C[C@@H](/C=C/[C@H]2CCC(=O)N2CCCCCCC(=O)O)O	Ki = 71000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BJ03GV	Methyl 7-[(1R,2S)-2-[3-(1-hydroxyhexyl)phenyl]-5-oxocyclopentyl]heptanoate	Investigative	59465575	C25H38O4	402.6	CCCCCC(C1=CC=CC(=C1)[C@H]2CCC(=O)[C@@H]2CCCCCCC(=O)OC)O	Ki = 50000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BOD26I	7-[(R)-2-((E)-(S)-4-Cyclobutyl-3-hydroxy-but-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid	Investigative	44290267	C19H31NO4	337.5	C1CC(C1)C[C@@H](/C=C/[C@H]2CCC(=O)N2CCCCCCC(=O)O)O	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BOD8P4	2-[1-[2-[N-(1,3-Benzodioxole-5-carbonyl)-4-methylanilino]ethyl]piperidin-4-yl]oxyacetic acid;hydrate;hydrochloride	Investigative	127047381	C24H31ClN2O7	495	CC1=CC=C(C=C1)N(CCN2CCC(CC2)OCC(=O)O)C(=O)C3=CC4=C(C=C3)OCO4.O.Cl	Ki ~ 50000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BP27DT	7-{(R)-2-[(E)-3-Hydroxy-3-(5-trifluoromethyl-furan-2-yl)-propenyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid	Investigative	44290314	C19H24F3NO5	403.4	C1CC(=O)N([C@H]1/C=C/C(C2=CC=C(O2)C(F)(F)F)O)CCCCCCC(=O)O	Ki = 58000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BP4T0O	Methyl 7-[(1R,2R,5S)-2-chloro-5-[4-(1-hydroxyhexyl)phenyl]cyclopentyl]heptanoate	Investigative	59465588	C25H39ClO3	423	CCCCCC(C1=CC=C(C=C1)[C@H]2CC[C@H]([C@@H]2CCCCCCC(=O)OC)Cl)O	Ki = 50000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BPM9C1	1-Tert-butyl-3-[2-[4-[(6-oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonylurea	Investigative	9959673	C33H33N3O4S	567.7	CC(C)(C)NC(=O)NS(=O)(=O)C1=CC=CC=C1C2=CC=C(C=C2)CN3C4=CC=CC=C4CCC5=CC=CC=C5C3=O	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BQ4S1E	1-[2-[4-[(6-Oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(2-thiophen-2-ylethyl)urea	Investigative	9938995	C35H31N3O4S2	621.8	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)NC(=O)NCCC6=CC=CS6	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BQ4WL1	7-{(R)-2-[(E)-3-Hydroxy-3-(1-phenyl-cyclopropyl)-propenyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid	Investigative	11696697	C23H31NO4	385.5	C1CC(=O)N([C@H]1/C=C/C(C2(CC2)C3=CC=CC=C3)O)CCCCCCC(=O)O	Ki = 164000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BR8VW6	3-(2-((6-(Benzyloxy)naphthalen-2-yl)methyl)phenyl)-N-(5-bromo-2-methoxyphenylsulfonyl)acrylamide	Investigative	15551228	C34H28BrNO5S	642.6	COC1=C(C=C(C=C1)Br)S(=O)(=O)NC(=O)/C=C/C2=CC=CC=C2CC3=CC4=C(C=C3)C=C(C=C4)OCC5=CC=CC=C5	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BRQM43	7-[(1R,2R,5S)-2-Chloro-5-[4-(1-hydroxyhexyl)phenyl]cyclopentyl]heptan-1-ol	Investigative	59465584	C24H39ClO2	395	CCCCCC(C1=CC=C(C=C1)[C@H]2CC[C@H]([C@@H]2CCCCCCCO)Cl)O	Ki = 50000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BS79ZT	7-[(2R)-2-[(E)-3-[3-(4-Chloro-2-methylphenyl)phenyl]-3-hydroxyprop-1-enyl]-5-oxopyrrolidin-1-yl]heptanoic acid	Investigative	10322469	C27H32ClNO4	470	CC1=C(C=CC(=C1)Cl)C2=CC(=CC=C2)C(/C=C/[C@H]3CCC(=O)N3CCCCCCC(=O)O)O	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BSR43T	Schembl20719106	Investigative	49850345	C21H18N2O4	362.4	CC(C)C1(C(=O)NC(=O)O1)C2=CC=C(NC2=O)C3=CC4=CC=CC=C4C=C3	IC50 ~ 50118.72 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BSU13O	Methyl 7-[(1R,2R,5S)-2-fluoro-5-[4-(1-hydroxyhexyl)phenyl]cyclopentyl]heptanoate	Investigative	59465590	C25H39FO3	406.6	CCCCCC(C1=CC=C(C=C1)[C@H]2CC[C@H]([C@@H]2CCCCCCC(=O)OC)F)O	Ki = 50000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BSY72X	1-Butyl-3-[2-[4-[(6-oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonylurea	Investigative	9872741	C33H33N3O4S	567.7	CCCCNC(=O)NS(=O)(=O)C1=CC=CC=C1C2=CC=C(C=C2)CN3C4=CC=CC=C4CCC5=CC=CC=C5C3=O	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BTE9C5	7-{(R)-2-[(E)-3-Hydroxy-3-(3-trifluoromethyl-phenyl)-propenyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid	Investigative	44289977	C21H26F3NO4	413.4	C1CC(=O)N([C@H]1/C=C/C(C2=CC(=CC=C2)C(F)(F)F)O)CCCCCCC(=O)O	Ki = 68000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BUS9X3	alpha-Methyl-N-[4'-(6-oxo-5,6,11,12-tetrahydrodibenzo[b,f]azocine-5-ylmethyl)-2-biphenylylsulfonyl]benzeneacetamide	Investigative	9938626	C37H32N2O4S	600.7	CC(C1=CC=CC=C1)C(=O)NS(=O)(=O)C2=CC=CC=C2C3=CC=C(C=C3)CN4C5=CC=CC=C5CCC6=CC=CC=C6C4=O	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BV9AM7	1-Benzyl-1-[2-[4-[(6-oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(2-phenylethyl)urea	Investigative	15491230	C44H39N3O4S	705.9	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)N(CC6=CC=CC=C6)C(=O)NCCC7=CC=CC=C7	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BWA0M2	1-Benzyl-3-[2-[4-[(6-oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonylurea	Investigative	9916766	C36H31N3O4S	601.7	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)NC(=O)NCC6=CC=CC=C6	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BWE3X7	Methyl 7-[(5S)-5-[4-(1-hydroxyhexyl)phenyl]cyclopenten-1-yl]heptanoate	Investigative	59465592	C25H38O3	386.6	CCCCCC(C1=CC=C(C=C1)[C@H]2CCC=C2CCCCCCC(=O)OC)O	Ki = 50000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BWE7Q9	1-Methyl-1-[2-[4-[(6-oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(2-phenylethyl)urea	Investigative	15491229	C38H35N3O4S	629.8	CN(C(=O)NCCC1=CC=CC=C1)S(=O)(=O)C2=CC=CC=C2C3=CC=C(C=C3)CN4C5=CC=CC=C5CCC6=CC=CC=C6C4=O	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BWNO89	4''-(Benzyloxy)-1,1':3',1''-terbenzene-2-propionic acid	Investigative	21362863	C28H24O3	408.5	C1=CC=C(C=C1)COC2=CC=C(C=C2)C3=CC(=CC=C3)C4=CC=CC=C4CCC(=O)O	Ki ~ 97000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BX2PY8	1-[2-[4-[(6-Oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)methyl]phenyl]phenyl]sulfonyl-3-(2-phenylethyl)urea	Investigative	9830442	C37H33N3O4S	615.7	C1CC2=CC=CC=C2N(C(=O)C3=CC=CC=C31)CC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)NC(=O)NCCC6=CC=CC=C6	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BZ1YN8	alpha,alpha-Dimethyl-N-[4'-(6-oxo-5,6,11,12-tetrahydrodibenzo[b,f]azocine-5-ylmethyl)-2-biphenylylsulfonyl]benzenepropanamide	Investigative	9895436	C39H36N2O4S	628.8	CC(C)(CC1=CC=CC=C1)C(=O)NS(=O)(=O)C2=CC=CC=C2C3=CC=C(C=C3)CN4C5=CC=CC=C5CCC6=CC=CC=C6C4=O	Ki ~ 100000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	BZYM67	7-[(1R,2S)-2-[3-(1-Hydroxyhexyl)phenyl]-5-oxocyclopentyl]heptanoic acid	Investigative	59465595	C24H36O4	388.5	CCCCCC(C1=CC=CC(=C1)[C@H]2CCC(=O)[C@@H]2CCCCCCC(=O)O)O	EC50 = 50000 nM	Poor binder
T38529	Prostaglandin E2 receptor EP2	D07UDT	L-798,106	Investigative	15551229	C27H22BrNO4S	536.4	COC1=C(C=C(C=C1)Br)S(=O)(=O)NC(=O)/C=C/C2=CC=CC=C2CC3=CC4=CC=CC=C4C=C3	Ki ~ 50000 nM	Poor binder