TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T42658 Herpesvirus ubiquitin-specific protease B0RW8I Chembl4290072 Investigative 134451499 C27H31N3O3 445.6 C[C@H](CC(=O)N1CCC(CC1)(CN2C=NC(=CC2=O)CC3=CC=CC=C3)O)C4=CC=CC=C4 IC50 = 90000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B2RQ6F 1-(5-((3,4-Dichlorophenyl)thio)thiazol-2-yl)ethanone Investigative 90479863 C11H7Cl2NOS2 304.2 CC(=O)C1=NC=C(S1)SC2=CC(=C(C=C2)Cl)Cl IC50 ~ 50000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B42VUY 4-(3-Pyrrolidin-3-yl-1,2,4-oxadiazol-5-yl)phenol Investigative 136699782 C12H13N3O2 231.25 C1CNCC1C2=NOC(=N2)C3=CC=C(C=C3)O IC50 = 132000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B4MI3G 1-(5-((3,4-Dimethoxyphenyl)thio)-4-nitrothiazol-2-yl)ethanone Investigative 118352365 C13H12N2O5S2 340.4 CC(=O)C1=NC(=C(S1)SC2=CC(=C(C=C2)OC)OC)[N+](=O)[O-] IC50 ~ 50000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B5D6KF 4-(3-Piperidin-4-yl-1,2,4-oxadiazol-5-yl)phenol Investigative 137002862 C13H15N3O2 245.28 C1CNCCC1C2=NOC(=N2)C3=CC=C(C=C3)O IC50 = 97700 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B5J3TU Chembl4292642 Investigative 134451347 C21H24N4O3S2 444.6 CSC1=NC2=C(S1)C(=O)N(C=N2)CC3(CCN(CC3)C(=O)CCC4=CC=CC=C4)O IC50 = 130000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B5PC9F 4-[3-(1-Methylpiperidin-4-yl)-1,2,4-oxadiazol-5-yl]phenol Investigative 135567363 C14H17N3O2 259.3 CN1CCC(CC1)C2=NOC(=N2)C3=CC=C(C=C3)O IC50 = 79200 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B6G5SF Chembl4288834 Investigative 145992545 C21H23N3O3S 397.5 C1CN(CCC1(CN2C=NC3=C(C2=O)SC=C3)O)C(=O)CCC4=CC=CC=C4 IC50 = 78000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B6KI3V Chembl4292244 Investigative 134451350 C21H23N3O4 381.4 C1CN(CCC1(CN2C=NC3=C(C2=O)OC=C3)O)C(=O)CCC4=CC=CC=C4 IC50 = 115000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B7OS2Z 1-[5-[(3,4-Dichlorophenyl)methylamino]-4-nitro-1,3-thiazol-2-yl]ethanone Investigative 118352333 C12H9Cl2N3O3S 346.2 CC(=O)C1=NC(=C(S1)NCC2=CC(=C(C=C2)Cl)Cl)[N+](=O)[O-] IC50 ~ 50000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B87LRH 1-(5-Phenylsulfanyl-4-nitro-2-thienyl)ethanone Investigative 71453283 C12H9NO3S2 279.3 CC(=O)C1=CC(=C(S1)SC2=CC=CC=C2)[N+](=O)[O-] IC50 ~ 50000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B8HQ0G 1-(5-((2,3-Dichlorophenyl)thio)thiazol-2-yl)ethanone Investigative 90479865 C11H7Cl2NOS2 304.2 CC(=O)C1=NC=C(S1)SC2=C(C(=CC=C2)Cl)Cl IC50 ~ 50000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease B8Y2ZX 4-[3-(1-Methylpyrrolidin-3-yl)-1,2,4-oxadiazol-5-yl]phenol Investigative 137649194 C13H15N3O2 245.28 CN1CCC(C1)C2=NOC(=N2)C3=CC=C(C=C3)O IC50 = 131000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease BBR5Q4 Chembl4280933 Investigative 134451421 C21H23N3O4 381.4 C1CN(CCC1(CN2C=NC3=C(C2=O)C=CO3)O)C(=O)CCC4=CC=CC=C4 IC50 = 87000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease BE1L4H 3,5-Bis(4-hydroxyphenyl)pyridine Investigative 10422855 C17H13NO2 263.29 C1=CC(=CC=C1C2=CC(=CN=C2)C3=CC=C(C=C3)O)O IC50 ~ 50000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease BKMA48 1-(5-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiazol-2-yl)ethyl benzoate Investigative 118352355 C17H11Cl2N3O4S2 456.3 CC(C1=NC(=C(S1)SC2=C(C=NC=C2Cl)Cl)[N+](=O)[O-])OC(=O)C3=CC=CC=C3 IC50 ~ 50000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease BN41SV 4-[2-Amino-4-ethyl-5-(2-methylindazol-6-yl)-3-pyridyl]phenol Investigative 122531790 C21H20N4O 344.4 CCC1=C(C(=NC=C1C2=CC3=NN(C=C3C=C2)C)N)C4=CC=C(C=C4)O EC50 ~ 50000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease BNV4B1 Chebi:149900 Investigative 86276129 C27H31N3O2 429.6 C[C@H](C1=CC=CC2=CC=CC=C21)N3CCC(CC3)C(=O)NCC4=CC(=CC=C4)NC(=O)C IC50 ~ 100000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease BT01BA Chembl4287544 Investigative 145993154 C21H22BrN3O3S 476.4 C1CN(CCC1(CN2C=NC3=C(C2=O)SC(=C3)Br)O)C(=O)CCC4=CC=CC=C4 IC50 = 60000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease BUAF17 1-(5-((3-Methoxyphenyl)thio)-4-nitrothiazol-2-yl)ethanone Investigative 118352370 C12H10N2O4S2 310.4 CC(=O)C1=NC(=C(S1)SC2=CC=CC(=C2)OC)[N+](=O)[O-] IC50 ~ 50000 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease BWE84V 4-(4-Piperidin-4-yl-1,3-oxazol-2-yl)phenol Investigative 137637373 C14H16N2O2 244.29 C1CNCCC1C2=COC(=N2)C3=CC=C(C=C3)O IC50 = 85200 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease BXW9V1 Chembl4128728 Investigative 145963452 C21H20N4O 344.4 CCC1=C(C(=NC=C1C2=CC3=C(C=C2)N(N=C3)C)N)C4=CC=C(C=C4)O IC50 ~ 63300 nM Poor binder T42658 Herpesvirus ubiquitin-specific protease BZPO13 1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethyl acetate Investigative 118352334 C12H9Cl2N3O4S2 394.3 CC(C1=NC(=C(S1)SC2=C(C=NC=C2Cl)Cl)[N+](=O)[O-])OC(=O)C IC50 ~ 50000 nM Poor binder