TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T42881	Cytomegalovirus Protease	B1FQD4	N-[2-[(3Ar,6R,6aS)-4-(cyclopropanecarbonyl)-6-methyl-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrol-1-yl]-2-oxoethyl]-5-(dimethylamino)-N-methylnaphthalene-1-sulfonamide	Investigative	44295946	C26H32N4O5S	512.6	C[C@@H]1[C@H]2[C@@H](CCN2C(=O)CN(C)S(=O)(=O)C3=CC=CC4=C3C=CC=C4N(C)C)N(C1=O)C(=O)C5CC5	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	B2SLP9	4-((2R,3S)-1-Benzylcarbamoyl-3-methyl-4-oxo-azetidin-2-yloxy)-benzoic acid	Investigative	478975	C19H18N2O5	354.4	C[C@H]1[C@H](N(C1=O)C(=O)NCC2=CC=CC=C2)OC3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	B36DAK	(3S,3Ar,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(3-isopropoxy-benzenesulfonyl)-pyrrolidine-2-carbonyl]-3-methyl-hexahydro-pyrrolo[3,2-b]pyrrol-2-one	Investigative	511083	C25H33N3O6S	503.6	C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]3CCCN3S(=O)(=O)C4=CC=CC(=C4)OC(C)C)N(C1=O)C(=O)C5CC5	IC50 = 65000 nM	Poor binder
T42881	Cytomegalovirus Protease	B4L1JD	[(2R,3S)-3-Methyl-4-oxo-1-(phenylcarbamoyl)azetidin-2-yl] acetate	Investigative	478970	C13H14N2O4	262.26	C[C@H]1[C@H](N(C1=O)C(=O)NC2=CC=CC=C2)OC(=O)C	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	B6NQC4	4-((R)-1-Benzylcarbamoyl-4-oxo-azetidin-2-yloxy)-benzoic acid	Investigative	478974	C18H16N2O5	340.3	C1[C@H](N(C1=O)C(=O)NCC2=CC=CC=C2)OC3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	B6X4KP	(3Ar,6R,6aS)-1-(1-Tosylprolyl)-4-acetyl-5-oxo-6-methyloctahydropyrrolo[3,2-b]pyrrole	Investigative	11037447	C21H27N3O5S	433.5	C[C@@H]1[C@H]2[C@@H](CCN2C(=O)[C@@H]3CCCN3S(=O)(=O)C4=CC=C(C=C4)C)N(C1=O)C(=O)C	IC50 = 159000 nM	Poor binder
T42881	Cytomegalovirus Protease	B7HCD0	4-((2R,3R)-1-Benzylcarbamoyl-3-ethyl-4-oxo-azetidin-2-yloxy)-benzoic acid	Investigative	479061	C20H20N2O5	368.4	CC[C@@H]1[C@H](N(C1=O)C(=O)NCC2=CC=CC=C2)OC3=CC=C(C=C3)C(=O)O	IC50 = 50000 nM	Poor binder
T42881	Cytomegalovirus Protease	B9LM0J	4-Acetyl-1-(1-benzoyl-pyrrolidine-2-carbonyl)-6-methyl-hexahydro-cyclopenta[b]pyrrol-5-one	Investigative	10894271	C21H25N3O4	383.4	C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]3CCCN3C(=O)C4=CC=CC=C4)N(C1=O)C(=O)C	IC50 = 50000 nM	Poor binder
T42881	Cytomegalovirus Protease	B9QSC8	Acetic acid (R)-1-isopropylcarbamoyl-4-oxo-azetidin-2-yl ester	Investigative	478964	C9H14N2O4	214.22	CC(C)NC(=O)N1[C@@H](CC1=O)OC(=O)C	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	B9TF7S	(3S,3Ar,6aS)-4-[(S)-1-(5-Dimethylamino-naphthalene-1-sulfonyl)-pyrrolidine-2-carbonyl]-3-methyl-1-(2,2,3,3-tetramethyl-cyclopropanecarbonyl)-hexahydro-pyrrolo[3,2-b]pyrrol-2-one	Investigative	493464	C32H42N4O5S	594.8	C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]3CCCN3S(=O)(=O)C4=CC=CC5=C4C=CC=C5N(C)C)N(C1=O)C(=O)C6C(C6(C)C)(C)C	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	BBK04P	Acetic acid (R)-1-ethylcarbamoyl-4-oxo-azetidin-2-yl ester	Investigative	478963	C8H12N2O4	200.19	CCNC(=O)N1[C@@H](CC1=O)OC(=O)C	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	BBV9K2	1-Acetyl-3-methyl-4-(2-phenoxy-acetyl)-hexahydro-pyrrolo[3,2-b]pyrrol-2-one	Investigative	44295781	C17H20N2O4	316.35	C[C@H]1C2[C@H](CCN2C(=O)COC3=CC=CC=C3)N(C1=O)C(=O)C	IC50 = 63000 nM	Poor binder
T42881	Cytomegalovirus Protease	BBX10I	Acetic acid (R)-1-benzylcarbamoyl-3,3-dimethyl-4-oxo-azetidin-2-yl ester	Investigative	478967	C15H18N2O4	290.31	CC(=O)O[C@@H]1C(C(=O)N1C(=O)NCC2=CC=CC=C2)(C)C	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	BE6S4C	Tert-butyl 2-[4-[[4-oxo-1-[[(1R)-1-phenylethyl]carbamoyl]azetidin-2-yl]sulfanylmethyl]phenyl]acetate	Investigative	482289	C25H30N2O4S	454.6	C[C@H](C1=CC=CC=C1)NC(=O)N2C(CC2=O)SCC3=CC=C(C=C3)CC(=O)OC(C)(C)C	IC50 = 75000 nM	Poor binder
T42881	Cytomegalovirus Protease	BFEU73	4-((R)-1-Isopropylcarbamoyl-4-oxo-azetidin-2-yloxy)-benzoic acid	Investigative	478972	C14H16N2O5	292.29	CC(C)NC(=O)N1[C@@H](CC1=O)OC2=CC=C(C=C2)C(=O)O	IC50 = 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	BFR1L3	4-((R)-4-Oxo-1-phenylcarbamoyl-azetidin-2-yloxy)-benzoic acid	Investigative	478973	C17H14N2O5	326.3	C1[C@H](N(C1=O)C(=O)NC2=CC=CC=C2)OC3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	BG4C8X	Benzyl (3aS,6S)-4-[(2S,3S)-2,3-dimethylcyclopropanecarbonyl]-6-methyl-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	71461732	C21H26N2O4	370.4	C[C@H]1[C@@H](C1C(=O)N2[C@H]3CCN(C3[C@@H](C2=O)C)C(=O)OCC4=CC=CC=C4)C	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	BGIP47	1-Acetyl-3-methyl-4-(2-oxo-3-phenyl-propyl)-hexahydro-pyrrolo[3,2-b]pyrrol-2-one	Investigative	44295804	C18H22N2O3	314.4	C[C@H]1C2[C@H](CCN2CC(=O)CC3=CC=CC=C3)N(C1=O)C(=O)C	IC50 = 79000 nM	Poor binder
T42881	Cytomegalovirus Protease	BI3M2F	(3S,3Ar,6aS)-3-Methyl-2-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1,4-dicarboxylic acid 4-benzyl ester 1-methyl ester	Investigative	493456	C17H20N2O5	332.4	C[C@H]1[C@@H]2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)OC	IC50 = 148000 nM	Poor binder
T42881	Cytomegalovirus Protease	BK7LT2	Acetic acid (R)-3,3-diethyl-1-methylcarbamoyl-4-oxo-azetidin-2-yl ester	Investigative	478968	C11H18N2O4	242.27	CCC1([C@H](N(C1=O)C(=O)NC)OC(=O)C)CC	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	BM32KN	Acetic acid (R)-1-butylcarbamoyl-4-oxo-azetidin-2-yl ester	Investigative	478965	C10H16N2O4	228.24	CCCCNC(=O)N1[C@@H](CC1=O)OC(=O)C	IC50 = 68000 nM	Poor binder
T42881	Cytomegalovirus Protease	BQP9V4	Benzyl (3aS,6S,6aR)-4-[(2S,3R)-2,3-dimethylcyclopropanecarbonyl]-6-methyl-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	490590	C21H26N2O4	370.4	C[C@@H]1[C@@H](C1C(=O)N2[C@H]3CCN([C@@H]3[C@@H](C2=O)C)C(=O)OCC4=CC=CC=C4)C	IC50 = 72000 nM	Poor binder
T42881	Cytomegalovirus Protease	BS71KQ	4-Isobutyryl-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	44296004	C19H24N2O4	344.4	C[C@H]1C2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)C(C)C	IC50 = 126000 nM	Poor binder
T42881	Cytomegalovirus Protease	BS75IB	[(2R,3R)-3-Methyl-4-oxo-1-(phenylcarbamoyl)azetidin-2-yl] acetate	Investigative	478971	C13H14N2O4	262.26	C[C@@H]1[C@H](N(C1=O)C(=O)NC2=CC=CC=C2)OC(=O)C	IC50 = 86000 nM	Poor binder
T42881	Cytomegalovirus Protease	BT1VM5	4-((2R,3S)-1-Benzylcarbamoyl-3-ethyl-4-oxo-azetidin-2-yloxy)-benzoic acid	Investigative	479060	C20H20N2O5	368.4	CC[C@H]1[C@H](N(C1=O)C(=O)NCC2=CC=CC=C2)OC3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	BUE94R	Benzyl 4-acetyl-6-methyl-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	490579	C17H20N2O4	316.35	CC1C2C(CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)C	IC50 = 110000 nM	Poor binder
T42881	Cytomegalovirus Protease	BUM04R	Benzyl (3aS,6S)-4-[(2S,3R)-2,3-dimethylcyclopropanecarbonyl]-6-methyl-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	71461709	C21H26N2O4	370.4	C[C@@H]1[C@@H](C1C(=O)N2[C@H]3CCN(C3[C@@H](C2=O)C)C(=O)OCC4=CC=CC=C4)C	IC50 = 72000 nM	Poor binder
T42881	Cytomegalovirus Protease	BV7B4O	(2R,3S)-N-Benzyl-2-[4-(2,2-dimethylpropanoyl)phenoxy]-3-methyl-4-oxoazetidine-1-carboxamide	Investigative	44347852	C23H26N2O4	394.5	C[C@H]1[C@H](N(C1=O)C(=O)NCC2=CC=CC=C2)OC3=CC=C(C=C3)C(=O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T42881	Cytomegalovirus Protease	BVM13K	4-(3-Hydroxy-propionyl)-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester	Investigative	44296005	C18H22N2O5	346.4	C[C@H]1C2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)CCO	IC50 = 133000 nM	Poor binder
T42881	Cytomegalovirus Protease	BZPK93	Benzyl (3aS,6S)-4-acetyl-6-methyl-5-oxo-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrole-1-carboxylate	Investigative	44295937	C17H20N2O4	316.35	C[C@H]1C2[C@H](CCN2C(=O)OCC3=CC=CC=C3)N(C1=O)C(=O)C	IC50 = 79000 nM	Poor binder