TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T44282	Mitochondrial aldehyde dehydrogenase	B53WVD	1-[(4-Methylpiperazin-1-yl)methyl]indole-2,3-dione	Investigative	2166081	C14H17N3O2	259.3	CN1CCN(CC1)CN2C3=CC=CC=C3C(=O)C2=O	IC50 ~ 100000 nM	Poor binder
T44282	Mitochondrial aldehyde dehydrogenase	B78LBR	1-[(4-Benzylpiperazin-1-yl)methyl]indole-2,3-dione	Investigative	1912440	C20H21N3O2	335.4	C1CN(CCN1CC2=CC=CC=C2)CN3C4=CC=CC=C4C(=O)C3=O	IC50 ~ 100000 nM	Poor binder
T44282	Mitochondrial aldehyde dehydrogenase	BCIU04	1-[[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]methyl]-5-bromoindole-2,3-dione	Investigative	2296065	C21H20BrN3O4	458.3	C1CN(CCN1CC2=CC3=C(C=C2)OCO3)CN4C5=C(C=C(C=C5)Br)C(=O)C4=O	IC50 ~ 100000 nM	Poor binder
T44282	Mitochondrial aldehyde dehydrogenase	BCVZ07	8-{[Benzyl(methyl)amino]methyl}-1,3-dimethyl-7-(3-methylbutyl)-3,7-dihydro-1H-purine-2,6-dione	Investigative	666623	C21H29N5O2	383.5	CC(C)CCN1C(=NC2=C1C(=O)N(C(=O)N2C)C)CN(C)CC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T44282	Mitochondrial aldehyde dehydrogenase	BEFY20	7-Butyl-8-[[4-(3-chlorophenyl)-1-piperazinyl]methyl]-1,3-dimethylpurine-2,6-dione	Investigative	666267	C22H29ClN6O2	445	CCCCN1C(=NC2=C1C(=O)N(C(=O)N2C)C)CN3CCN(CC3)C4=CC(=CC=C4)Cl	IC50 ~ 100000 nM	Poor binder
T44282	Mitochondrial aldehyde dehydrogenase	BFB59Q	1,3-Dimethyl-7-(3-methylbutyl)-8-(morpholin-4-ylmethyl)-3,7-dihydro-1H-purine-2,6-dione	Investigative	4653534	C17H27N5O3	349.4	CC(C)CCN1C(=NC2=C1C(=O)N(C(=O)N2C)C)CN3CCOCC3	IC50 ~ 100000 nM	Poor binder
T44282	Mitochondrial aldehyde dehydrogenase	BO6NA7	1-Morpholin-4-ylmethyl-1H-indole-2,3-dione	Investigative	262696	C13H14N2O3	246.26	C1COCCN1CN2C3=CC=CC=C3C(=O)C2=O	IC50 ~ 100000 nM	Poor binder
T44282	Mitochondrial aldehyde dehydrogenase	BOH5P6	1,3-Dimethyl-7-(3-methylbutyl)-8-[(4-methylpiperidin-1-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione	Investigative	4999777	C19H31N5O2	361.5	CC1CCN(CC1)CC2=NC3=C(N2CCC(C)C)C(=O)N(C(=O)N3C)C	IC50 ~ 100000 nM	Poor binder
T44282	Mitochondrial aldehyde dehydrogenase	BV9E0P	1-[(2E)-3-Phenylprop-2-en-1-yl]-1H-indole-2,3-dione	Investigative	2057118	C17H13NO2	263.29	C1=CC=C(C=C1)/C=C/CN2C3=CC=CC=C3C(=O)C2=O	IC50 ~ 100000 nM	Poor binder
T44282	Mitochondrial aldehyde dehydrogenase	BVX9T0	1-{[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]methyl}-1H-indole-2,3-dione	Investigative	1966642	C21H21N3O4	379.4	C1CN(CCN1CC2=CC3=C(C=C2)OCO3)CN4C5=CC=CC=C5C(=O)C4=O	IC50 ~ 100000 nM	Poor binder
T44282	Mitochondrial aldehyde dehydrogenase	D0O0LU	1-benzyl-1H-indole-2,3-dione	Investigative	264734	C15H11NO2	237.25	C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=O)C2=O	IC50 = 82000 nM	Poor binder