TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T44916	Embryonic ectoderm development protein	D0Y2HR	Astemizole	Withdrawn from market	2247	C28H31FN4O	458.6	COC1=CC=C(C=C1)CCN2CCC(CC2)NC3=NC4=CC=CC=C4N3CC5=CC=C(C=C5)F	IC50 = 93800 nM	Poor binder
T44916	Embryonic ectoderm development protein	B01TQY	3-(1-Benzofuran-7-ylmethyl)piperidine	Investigative	84784098	C14H17NO	215.29	C1CC(CNC1)CC2=CC=CC3=C2OC=C3	IC50 = 95000 nM	Poor binder
T44916	Embryonic ectoderm development protein	B6ICS8	3-(3-Methoxybenzyl)piperidine	Investigative	17039514	C13H19NO	205.3	COC1=CC=CC(=C1)CC2CCCNC2	IC50 = 95000 nM	Poor binder
T44916	Embryonic ectoderm development protein	B7O2YB	9-Benzyl-5-chloro-7,8,9,10-tetrahydro-[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile	Investigative	118996396	C17H14ClN5	323.8	C1CN(CC2=C1C(=C(N3C2=NN=C3)Cl)C#N)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T44916	Embryonic ectoderm development protein	B7TRL9	(3R,4S)-N,N-Dimethyl-1-[(2-methylimidazo[1,2-a]pyrimidin-3-yl)methyl]-4-(1-methylindol-3-yl)pyrrolidin-3-amine	Investigative	137657817	C23H28N6	388.5	CC1=C(N2C=CC=NC2=N1)CN3C[C@@H]([C@H](C3)N(C)C)C4=CN(C5=CC=CC=C54)C	Ki ~ 50000 nM	Poor binder
T44916	Embryonic ectoderm development protein	B8M9WI	(3R,4S)-1-(Imidazo[1,2-a]pyridin-7-ylmethyl)-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine	Investigative	137641805	C23H27N5	373.5	CN1C=C(C2=CC=CC=C21)[C@H]3CN(C[C@@H]3N(C)C)CC4=CC5=NC=CN5C=C4	Ki ~ 50000 nM	Poor binder
T44916	Embryonic ectoderm development protein	B8WR7T	(3R,4S)-1-[(1-Ethyl-3-methylpyrazol-4-yl)methyl]-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine	Investigative	137646001	C22H31N5	365.5	CCN1C=C(C(=N1)C)CN2C[C@@H]([C@H](C2)N(C)C)C3=CN(C4=CC=CC=C43)C	Ki ~ 50000 nM	Poor binder
T44916	Embryonic ectoderm development protein	B9TLO5	3-[(4-Fluoro-3-methoxyphenyl)methyl]piperidine	Investigative	84789118	C13H18FNO	223.29	COC1=C(C=CC(=C1)CC2CCCNC2)F	IC50 = 119000 nM	Poor binder
T44916	Embryonic ectoderm development protein	BG23DO	3-(2-Methoxy-benzyl)-piperidine	Investigative	5005916	C13H19NO	205.3	COC1=CC=CC=C1CC2CCCNC2	IC50 = 146000 nM	Poor binder
T44916	Embryonic ectoderm development protein	BRGJ07	3-(1-Benzofuran-7-ylmethyl)piperidine-1-carboxamide	Investigative	137642432	C15H18N2O2	258.32	C1CC(CN(C1)C(=O)N)CC2=CC=CC3=C2OC=C3	IC50 = 174000 nM	Poor binder
T44916	Embryonic ectoderm development protein	BRV42N	(3R,4S)-N,N-Dimethyl-1-[(1-methylimidazol-2-yl)methyl]-4-(1-methylindol-3-yl)pyrrolidin-3-amine	Investigative	137636483	C20H27N5	337.5	CN1C=CN=C1CN2C[C@@H]([C@H](C2)N(C)C)C3=CN(C4=CC=CC=C43)C	Ki ~ 50000 nM	Poor binder