TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T45262 Corticotropin-releasing factor receptor 1 B2LFA4 4-Methyl-2-(2,4,6-trichloro-phenylamino)-thiazole-5-carboxylic acid bis-(2-methoxy-ethyl)-amide Investigative 10297799 C17H20Cl3N3O3S 452.8 CC1=C(SC(=N1)NC2=C(C=C(C=C2Cl)Cl)Cl)C(=O)N(CCOC)CCOC Ki = 51000 nM Poor binder T45262 Corticotropin-releasing factor receptor 1 BHE37D 2-N-(2,6-Diethylphenyl)-6-methyl-4-N-[[4-(trifluoromethyl)phenyl]methyl]-1,3,5-triazine-2,4-diamine Investigative 10835652 C22H24F3N5 415.5 CCC1=C(C(=CC=C1)CC)NC2=NC(=NC(=N2)NCC3=CC=C(C=C3)C(F)(F)F)C Ki = 55000 nM Poor binder T45262 Corticotropin-releasing factor receptor 1 BI9V6E (5-Piperidin-1-ylmethyl-4-trifluoromethyl-thiazol-2-yl)-(2,4,6-trichloro-phenyl)-amine Investigative 44389084 C16H15Cl3F3N3S 444.7 C1CCN(CC1)CC2=C(N=C(S2)NC3=C(C=C(C=C3Cl)Cl)Cl)C(F)(F)F Ki = 55000 nM Poor binder