TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T48330	Large neutral amino acids transporter 1	D01CRB	L-Tyrosine	Approved	6057	C9H11NO3	181.19	C1=CC(=CC=C1C[C@@H](C(=O)O)N)O	IC50 = 68000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	D05EJG	L-Tryptophan	Approved	6305	C11H12N2O2	204.22	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)N	IC50 = 160000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	D08HVR	Levodopa	Approved	6047	C9H11NO4	197.19	C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O	IC50 = 100000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	D0R1CR	L-Phenylalanine	Approved	6140	C9H11NO2	165.19	C1=CC=C(C=C1)C[C@@H](C(=O)O)N	IC50 = 69000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	B2J7KG	alpha-Methyl-L-phenylalanine	Investigative	2724754	C10H13NO2	179.22	C[C@](CC1=CC=CC=C1)(C(=O)O)N	IC50 = 130000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	B3CS7W	Chembl4241017	Investigative	145984714	C12H15NO4	237.25	CC1=CC(=CC(=C1)C(=O)OC)C[C@@H](C(=O)O)N	IC50 = 95000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	B4D6QB	(2S)-2-Amino-3-[3-(hydroxymethyl)phenyl]propanoic acid	Investigative	67059715	C10H13NO3	195.21	C1=CC(=CC(=C1)CO)C[C@@H](C(=O)O)N	IC50 = 83000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	B4FVU7	(S)-2-Amino-3-(3-aminophenyl)propanoic acid	Investigative	53754520	C9H12N2O2	180.2	C1=CC(=CC(=C1)N)C[C@@H](C(=O)O)N	IC50 = 101000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	B9VDO5	(S)-2-Amino-3-(1-benzyl-1H-imidazol-4-yl)propanoic acid	Investigative	193138	C13H15N3O2	245.28	C1=CC=C(C=C1)CN2C=C(N=C2)C[C@@H](C(=O)O)N	IC50 = 170000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BB41FP	1-Methyl-L-histidine	Investigative	92105	C7H11N3O2	169.18	CN1C=C(N=C1)C[C@@H](C(=O)O)N	IC50 = 190000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BB59VC	3-(2-Pyridyl)-L-alanine	Investigative	2761499	C8H10N2O2	166.18	C1=CC=NC(=C1)C[C@@H](C(=O)O)N	IC50 = 160000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BCPX47	Chembl4248453	Investigative	68530773	C11H14N2O3	222.24	CC(=O)NC1=CC=CC(=C1)C[C@@H](C(=O)O)N	IC50 = 110000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BO0FS9	D-Methionine	Investigative	84815	C5H11NO2S	149.21	CSCC[C@H](C(=O)O)N	IC50 = 120000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BP8U0H	3-(3-Pyridyl)-L-alanine	Investigative	152953	C8H10N2O2	166.18	C1=CC(=CN=C1)C[C@@H](C(=O)O)N	IC50 = 69000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BPN0C6	Chembl4242607	Investigative	145984011	C12H15NO4	237.25	COC(=O)CC1=CC=CC(=C1)C[C@@H](C(=O)O)N	IC50 = 76000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BTPS90	Chembl4244666	Investigative	145985040	C11H13NO4	223.22	COC(=O)C1=CC=CC(=C1)C[C@H](C(=O)O)N	IC50 = 150000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BUG0O7	3-[(2S)-2-Amino-2-carboxyethyl]benzoic acid	Investigative	22854522	C10H11NO4	209.2	C1=CC(=CC(=C1)C(=O)O)C[C@@H](C(=O)O)N	IC50 = 130000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BUY5J2	Chembl4240451	Investigative	145985227	C11H14N2O3	222.24	CNC(=O)C1=CC=CC(=C1)C[C@@H](C(=O)O)N	IC50 = 96000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BWVC30	3-(4-Pyridyl)-L-alanine	Investigative	7009701	C8H10N2O2	166.18	C1=CN=CC=C1C[C@@H](C(=O)O)N	IC50 = 100000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	BYW84F	m-Acetylphenylalanine	Investigative	11521308	C11H13NO3	207.23	CC(=O)C1=CC=CC(=C1)C[C@@H](C(=O)O)N	IC50 = 92000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	D00XUE	(S)-2-amino-3-cyclohexylpropanoic acid	Investigative	712421	C9H17NO2	171.24	C1CCC(CC1)C[C@@H](C(=O)O)N	IC50 = 200000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	D05XGI	Meta-Tyrosine	Investigative	6950578	C9H11NO3	181.19	C1=CC(=CC(=C1)O)C[C@@H](C(=O)O)N	IC50 = 130000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	D0I8SK	L-isoleucine	Investigative	6306	C6H13NO2	131.17	CC[C@H](C)[C@@H](C(=O)O)N	IC50 = 140000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	D0LL5V	L-valine	Investigative	6287	C5H11NO2	117.15	CC(C)[C@@H](C(=O)O)N	IC50 = 68000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	D0PO8E	L-methionine	Investigative	6137	C5H11NO2S	149.21	CSCC[C@@H](C(=O)O)N	IC50 = 170000 nM	Poor binder
T48330	Large neutral amino acids transporter 1	D0W4MZ	L-leucine	Investigative	6106	C6H13NO2	131.17	CC(C)C[C@@H](C(=O)O)N	IC50 = 85000 nM	Poor binder