TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T50224	Ribosomal protein S6 kinase alpha-5	B1BIA9	Pyrrolopyridine, 9	Investigative	16719862	C18H15N3O	289.3	C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC=CC=C4	IC50 = 146000 nM	Poor binder
T50224	Ribosomal protein S6 kinase alpha-5	B3UI9B	1-(2-Hydroxy-2-methylpropyl)-N-(5-((7-methoxyquinolin-4-yl)oxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide	Investigative	24764449	C30H29N5O5	539.6	CC1=C(C(=O)N(N1CC(C)(C)O)C2=CC=CC=C2)C(=O)NC3=NC=C(C=C3)OC4=C5C=CC(=CC5=NC=C4)OC	IC50 = 100000 nM	Poor binder
T50224	Ribosomal protein S6 kinase alpha-5	B6TY8C	5-[3-Fluoro-4-[[6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl]oxy]phenyl]-2-(4-fluorophenylamino)-3-methylpyrimidin-4(3H)-one	Investigative	11858109	C34H33F2N5O5	629.7	CN1C(=O)C(=CN=C1NC2=CC=C(C=C2)F)C3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OCCCN6CCOCC6)OC)F	IC50 ~ 100000 nM	Poor binder
T50224	Ribosomal protein S6 kinase alpha-5	B82MQJ	Aminopyrimidine amide, 13b	Investigative	16118737	C31H30F3N7O2	589.6	CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C(=O)NC3=CN=C(N=C3)NC4=CC=C(C=C4)N5CCN(CC5)C	IC50 ~ 100000 nM	Poor binder
T50224	Ribosomal protein S6 kinase alpha-5	BPL30U	Lck Inhibitor	Investigative	11785878	C31H30N8O	530.6	CC1=C(C(=CC=C1)C)N2C(=O)C3=CN=C(N=C3N4C2=NC5=CC=CC=C54)NC6=CC=C(C=C6)N7CCN(CC7)C	IC50 ~ 100000 nM	Poor binder
T50224	Ribosomal protein S6 kinase alpha-5	BY06KG	4(3H)-Pyrimidinone,2-[(4-fluorophenyl)amino]-5-[5-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]-2-pyridinyl]-3-methyl-	Investigative	24769780	C33H33FN6O5	612.6	CN1C(=O)C(=CN=C1NC2=CC=C(C=C2)F)C3=NC=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OCCCN6CCOCC6)OC	IC50 = 52000 nM	Poor binder
T50224	Ribosomal protein S6 kinase alpha-5	D07OXC	AM7	Investigative	11650194	C35H35FN4O5	610.7	CN1C(=NC=C(C1=O)C2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OCCCN5CCOCC5)OC)F)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder