TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T50970	Endothelin-converting enzyme 1	B16HUV	(R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-phenyl-propionic acid	Investigative	44275764	C35H37N2O7P	628.6	C1=CC=C(C=C1)C[C@H](C(=O)O)NC(=O)C(CC2=CC=CC=C2)CP(=O)([C@H](CC3=CC=CC=C3)NC(=O)OCC4=CC=CC=C4)O	IC50 ~ 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	B2TY4V	(R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-5-guanidino-pentanoic acid	Investigative	44275795	C32H40N5O7P	637.7	C1=CC=C(C=C1)C[C@H](NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CC3=CC=CC=C3)C(=O)N[C@H](CCCN=C(N)N)C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	B38MAX	(S)-3-(1H-Indol-3-yl)-2-((S)-2-mercapto-4-methyl-pentanoylamino)-propionic acid	Investigative	44301375	C17H22N2O3S	334.4	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)S	IC50 = 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	B4F7WP	(R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-methyl-butyric acid	Investigative	44275416	C31H37N2O7P	580.6	CC(C)[C@H](C(=O)O)NC(=O)C(CC1=CC=CC=C1)CP(=O)([C@H](CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3)O	IC50 = 60000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	B4LGA0	2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-4-carbamoyl-butyric acid	Investigative	44275869	C31H36N3O8P	609.6	C1=CC=C(C=C1)C[C@H](NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CC3=CC=CC=C3)C(=O)NC(CCC(=O)N)C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	B7JD5C	4,5-Dimethoxy-6-thiophen-3-yl-pyridine-2-carboxylic acid	Investigative	44307703	C12H11NO4S	265.29	COC1=CC(=NC(=C1OC)C2=CSC=C2)C(=O)O	IC50 ~ 50000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	B7L8FJ	4,5-Dimethoxy-6-(1-methyl-1H-pyrrol-2-yl)-pyridine-2-carboxylic acid	Investigative	44307702	C13H14N2O4	262.26	CN1C=CC=C1C2=C(C(=CC(=N2)C(=O)O)OC)OC	IC50 ~ 50000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	B8VN0Q	(2R,3S)-2-[[2-Benzyl-3-[hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]propanoyl]amino]-3-hydroxybutanoic acid	Investigative	56668219	C30H35N2O8P	582.6	C[C@@H]([C@H](C(=O)O)NC(=O)C(CC1=CC=CC=C1)CP(=O)([C@H](CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3)O)O	IC50 ~ 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BB01LM	(R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-pentanedioic acid	Investigative	44275871	C31H35N2O9P	610.6	C1=CC=C(C=C1)C[C@H](NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CC3=CC=CC=C3)C(=O)N[C@H](CCC(=O)O)C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BBJ5U9	(2S)-2-[[(2S)-2-[[Ethoxy(hydroxy)phosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid	Investigative	10342348	C19H28N3O6P	425.4	CCOP(=O)(N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)O	IC50 = 109000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BD2V9Y	N-(Carboxymethyl)-N-(3-Phenylpropyl)glycyl-N-Methyl-L-Histidinamide	Investigative	54589400	C20H27N5O4	401.5	CNC(=O)[C@H](CC1=CN=CN1)NC(=O)CN(CCCC2=CC=CC=C2)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BDHM17	N-(Benzylphosphonyl)-L-Leu-L-Trp-OH	Investigative	10344688	C24H30N3O5P	471.5	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NP(=O)(CC3=CC=CC=C3)O	IC50 = 61000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BJ63ZY	6-Amino-2-{2-benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-hexanoic acid	Investigative	44275713	C32H40N3O7P	609.6	C1=CC=C(C=C1)C[C@H](NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CC3=CC=CC=C3)C(=O)NC(CCCCN)C(=O)O)O	IC50 = 60000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BJU2E4	2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-methyl-butyric acid	Investigative	44275937	C31H37N2O7P	580.6	CC(C)C(C(=O)O)NC(=O)C(CC1=CC=CC=C1)CP(=O)([C@H](CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3)O	IC50 = 80000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BK2X0P	(3S)-3-(Benzenesulfonyl)-N-hydroxyheptanamide	Investigative	10613145	C13H19NO4S	285.36	CCCC[C@@H](CC(=O)NO)S(=O)(=O)C1=CC=CC=C1	IC50 ~ 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BM3T4J	{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-acetic acid	Investigative	44275916	C28H31N2O7P	538.5	C1=CC=C(C=C1)C[C@H](NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CC3=CC=CC=C3)C(=O)NCC(=O)O)O	IC50 = 80000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BR1D6T	(S)-3-(1H-Indol-3-yl)-2-((R)-2-mercapto-4-methyl-pentanoylamino)-propionic acid	Investigative	44301550	C17H22N2O3S	334.4	CC(C)C[C@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)S	IC50 = 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BTU97O	Thiorphan	Investigative	3132	C12H15NO3S	253.32	C1=CC=C(C=C1)CC(CS)C(=O)NCC(=O)O	IC50 ~ 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BVYS37	6-Furan-3-yl-4,5-dimethoxy-pyridine-2-carboxylic acid	Investigative	44307550	C12H11NO5	249.22	COC1=CC(=NC(=C1OC)C2=COC=C2)C(=O)O	IC50 ~ 50000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BW65DQ	(3R)-3-(Benzenesulfonyl)-N-hydroxyheptanamide	Investigative	10493383	C13H19NO4S	285.36	CCCC[C@H](CC(=O)NO)S(=O)(=O)C1=CC=CC=C1	IC50 ~ 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	BZSW70	3-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-propionic acid	Investigative	44275459	C29H33N2O7P	552.6	C1=CC=C(C=C1)C[C@H](NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CC3=CC=CC=C3)C(=O)NCCC(=O)O)O	IC50 = 50000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	D02BTV	3-Benzenesulfinyl-heptanoic acid hydroxyamide	Investigative	9816867	C13H19NO3S	269.36	CCCCC(CC(=O)NO)S(=O)C1=CC=CC=C1	IC50 ~ 100000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	D08ELY	3-Benzenesulfonyl-heptanoic acid hydroxyamide	Investigative	9838786	C13H19NO4S	285.36	CCCCC(CC(=O)NO)S(=O)(=O)C1=CC=CC=C1	IC50 ~ 50000 nM	Poor binder
T50970	Endothelin-converting enzyme 1	D0N6CD	3-Cyclohexanesulfonyl-heptanoic acid hydroxyamide	Investigative	10565532	C13H25NO4S	291.41	CCCCC(CC(=O)NO)S(=O)(=O)C1CCCCC1	IC50 = 78000 nM	Poor binder