TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T51408	Adrenergic receptor beta-3	B0F7HP	(+/-)-N-[5-(2-Bromo-1-hydroxyethyl)isoxazol-3-yl]methanesulfonamide	Investigative	44423639	C10H19N3O4S	277.34	CC(C)(C)NCC(C1=CC(=NO1)NS(=O)(=O)C)O	Ki ~ 100000 nM	Poor binder
T51408	Adrenergic receptor beta-3	B1B3IC	N-[4-[2-[[(2S)-2-Hydroxy-3-[4-(methanesulfonamido)phenoxy]propyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide	Investigative	44574685	C25H30N4O5S	498.6	CS(=O)(=O)NC1=CC=C(C=C1)OC[C@H](CNCCC2=CC=C(C=C2)NC(=O)CC3=CC=CC=N3)O	EC50 ~ 100000 nM	Poor binder
T51408	Adrenergic receptor beta-3	B20VOR	4-(3,4,5-Trimethoxybenzyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-amine	Investigative	10544781	C16H21N3O3S	335.4	COC1=CC(=CC(=C1OC)OC)CC2C3=C(CCN2)N=C(S3)N	Ki = 67608.3 nM	Poor binder
T51408	Adrenergic receptor beta-3	B23IMZ	N-[4-[2-[[(2S)-2-Hydroxy-3-[(2-oxo-1,3-dihydrobenzimidazol-4-yl)oxy]propyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide	Investigative	44574688	C25H27N5O4	461.5	C1=CC=NC(=C1)CC(=O)NC2=CC=C(C=C2)CCNC[C@@H](COC3=CC=CC4=C3NC(=O)N4)O	EC50 ~ 100000 nM	Poor binder
T51408	Adrenergic receptor beta-3	B43TUH	N-[4-[2-[[(2S)-2-Hydroxy-3-pyridin-3-yloxypropyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide	Investigative	44574687	C23H26N4O3	406.5	C1=CC=NC(=C1)CC(=O)NC2=CC=C(C=C2)CCNC[C@@H](COC3=CN=CC=C3)O	EC50 ~ 100000 nM	Poor binder
T51408	Adrenergic receptor beta-3	B4AF6R	N-[4-[2-[[(2S)-3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide	Investigative	44574720	C30H30N4O3	494.6	C1=CC=C2C(=C1)C3=C(N2)C=CC=C3OC[C@H](CNCCC4=CC=C(C=C4)NC(=O)CC5=CC=CC=N5)O	EC50 ~ 100000 nM	Poor binder
T51408	Adrenergic receptor beta-3	B5S6KG	N-[4-[2-[[(2S)-2-Hydroxy-3-(1H-indol-4-yloxy)propyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide	Investigative	44574651	C26H28N4O3	444.5	C1=CC=NC(=C1)CC(=O)NC2=CC=C(C=C2)CCNC[C@@H](COC3=CC=CC4=C3C=CN4)O	EC50 ~ 100000 nM	Poor binder
T51408	Adrenergic receptor beta-3	B6XZG7	6-[beta,4-Dihydroxy-3-(methylsulfonylamino)phenethylamino]-7-phenylheptanoic acid	Investigative	19073112	C22H30N2O6S	450.6	CS(=O)(=O)NC1=C(C=CC(=C1)C(CNC(CCCCC(=O)O)CC2=CC=CC=C2)O)O	Ki = 87000 nM	Poor binder
T51408	Adrenergic receptor beta-3	B6YZ3S	(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxymethyl)-phosphonic acid	Investigative	44286964	C18H23ClNO5P	399.8	C[C@H](CC1=CC=C(C=C1)OCP(=O)(O)O)NC[C@@H](C2=CC(=CC=C2)Cl)O	Ki = 55300 nM	Poor binder
T51408	Adrenergic receptor beta-3	B7K8OE	N-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide	Investigative	44574686	C24H27N3O3	405.5	C1=CC=C(C=C1)OC[C@H](CNCCC2=CC=C(C=C2)NC(=O)CC3=CC=CC=N3)O	EC50 ~ 100000 nM	Poor binder
T51408	Adrenergic receptor beta-3	BAR3X7	N-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-2-(1-phenylimidazol-2-yl)acetamide	Investigative	44574759	C28H30N4O3	470.6	C1=CC=C(C=C1)N2C=CN=C2CC(=O)NC3=CC=C(C=C3)CCNC[C@@H](COC4=CC=CC=C4)O	EC50 ~ 100000 nM	Poor binder
T51408	Adrenergic receptor beta-3	BFH91G	3-(2-{(R)-2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-thiazol-5-yl)-propionic acid	Investigative	15221055	C17H21ClN2O3S	368.9	C[C@H](CC1=NC=C(S1)CCC(=O)O)NCC(C2=CC(=CC=C2)Cl)O	Ki = 146000 nM	Poor binder
T51408	Adrenergic receptor beta-3	BK7J1N	N-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]benzamide;hydrochloride	Investigative	49861313	C24H27ClN2O3	426.9	C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)CCNC[C@@H](COC3=CC=CC=C3)O.Cl	EC50 = 130000 nM	Poor binder
T51408	Adrenergic receptor beta-3	BM74IF	2-(1-Benzylbenzimidazol-2-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]acetamide	Investigative	44574825	C33H34N4O3	534.6	C1=CC=C(C=C1)CN2C3=CC=CC=C3N=C2CC(=O)NC4=CC=C(C=C4)CCNC[C@@H](COC5=CC=CC=C5)O	EC50 ~ 100000 nM	Poor binder
T51408	Adrenergic receptor beta-3	BP9SR7	2-(1-Benzylimidazol-2-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-N-propylacetamide	Investigative	44574913	C32H38N4O3	526.7	CCCN(C1=CC=C(C=C1)CCNC[C@@H](COC2=CC=CC=C2)O)C(=O)CC3=NC=CN3CC4=CC=CC=C4	EC50 ~ 100000 nM	Poor binder
T51408	Adrenergic receptor beta-3	BSO89E	(R)-N-(3-(2-Amino-1-hydroxyethyl)-2-fluoro-6-hydroxyphenyl)methanesulfonamide	Investigative	44444152	C9H13FN2O4S	264.28	CS(=O)(=O)NC1=C(C=CC(=C1F)[C@H](CN)O)O	Ki = 120000 nM	Poor binder
T51408	Adrenergic receptor beta-3	BXD1H8	(R,R)-(+)-{4-[2-{[2-(3-Bromoisoxazol-5-yl)-2-hydroxyethyl]-amino}propyl]phenoxy}acetic acid	Investigative	44423641	C16H19BrN2O5	399.24	C[C@H](CC1=CC=C(C=C1)OCC(=O)O)NC[C@H](C2=CC(=NO2)Br)O	Ki ~ 50000 nM	Poor binder
T51408	Adrenergic receptor beta-3	BYZ74L	2-(1-Benzylimidazol-2-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-N-methylacetamide	Investigative	44219630	C30H34N4O3	498.6	CN(C1=CC=C(C=C1)CCNC[C@@H](COC2=CC=CC=C2)O)C(=O)CC3=NC=CN3CC4=CC=CC=C4	EC50 ~ 100000 nM	Poor binder