TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T58454 Fibroblast growth factor receptor 2 B0WLH8 N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide Investigative 58056356 C17H12N4O2S 336.4 COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43 IC50 ~ 50000 nM Poor binder T58454 Fibroblast growth factor receptor 2 B43WPI 3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide Investigative 57325478 C19H20ClNO4 361.8 COC1=C(C=C(C=C1)C(=O)NC[C@H](CO)O)/C=C/C2=CC=C(C=C2)Cl IC50 ~ 50000 nM Poor binder T58454 Fibroblast growth factor receptor 2 B58TMC [6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate Investigative 24753787 C21H22ClN3O6S 479.9 CC1=C(C(=O)OC2=CC(=C(C=C12)Cl)OC(=O)N(C)C)CC3=CC(=CC=C3)NS(=O)(=O)NC IC50 ~ 50000 nM Poor binder T58454 Fibroblast growth factor receptor 2 B58USB Chembl4173432 Investigative 145950580 C15H12F2N2O 274.26 CCOC1=C(C(=C(C=C1)F)C2=CC3=C(C=C2)C=NN3)F IC50 = 52000 nM Poor binder T58454 Fibroblast growth factor receptor 2 B7N1WR 3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide Investigative 57325479 C19H20ClNO4 361.8 COC1=C(C=C(C=C1)C(=O)NC[C@@H](CO)O)/C=C/C2=CC=C(C=C2)Cl IC50 ~ 50000 nM Poor binder T58454 Fibroblast growth factor receptor 2 B8YTQ3 CID 49806721 Investigative 49806721 C28H30N4O2 454.6 CCC1=CC2=C(C=C1N3CCN(CC3)C4COC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C IC50 ~ 50000 nM Poor binder