TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T60182	Glucagon receptor	B08GZF	4-(4-Hydroxy-naphthalen-1-ylmethylene-hydrazinocarbonyl)-benzoic acid	Investigative	135542516	C19H14N2O4	334.3	C1=CC=C2C(=C1)C(=CC=C2O)/C=N/NC(=O)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	B1A8HE	4-Hydroxy-3-methoxy-benzoic acid (4-hydroxy-benzylidene)-hydrazide	Investigative	135447739	C15H14N2O4	286.28	COC1=C(C=CC(=C1)C(=O)N/N=C/C2=CC=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	B1D2OQ	4-Hydroxy-3-methoxy-benzoic acid (3-hydroxy-4-methoxy-benzylidene)-hydrazide	Investigative	11001603	C16H16N2O5	316.31	COC1=C(C=C(C=C1)/C=N/NC(=O)C2=CC(=C(C=C2)O)OC)O	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	B21JSB	5-[(1H-Benzimidazole-2-ylthio)acetyl]-2-hydroxybenzoic acid	Investigative	10687711	C16H12N2O4S	328.3	C1=CC=C2C(=C1)NC(=N2)SCC(=O)C3=CC(=C(C=C3)O)C(=O)O	Ki = 200000 nM	Poor binder
T60182	Glucagon receptor	B26CVM	4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide	Investigative	743974	C16H19NO3S	305.4	CC1=CC(=C(C(=C1)C)NS(=O)(=O)C2=CC=C(C=C2)OC)C	EC50 ~ 50118.72 nM	Poor binder
T60182	Glucagon receptor	B28PBY	3-Methoxy-benzoic acid (4-methoxy-naphthalen-1-ylmethylene)-hydrazide	Investigative	11045899	C20H18N2O3	334.4	COC1=CC=CC(=C1)C(=O)N/N=C/C2=CC=C(C3=CC=CC=C23)OC	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	B2L1NB	2-Chloro-4-[1-[4-(4-isopropylbenzyloxy)-3,5-dimethoxyphenyl]-(E)-methylideneaminosulfonamido]phenol	Investigative	44373564	C25H27ClN2O6S	519	CC(C)C1=CC=C(C=C1)COC2=C(C=C(C=C2OC)/C=N/NS(=O)(=O)C3=CC(=C(C=C3)O)Cl)OC	IC50 = 78300 nM	Poor binder
T60182	Glucagon receptor	B3CKX9	4-Amino-benzoic acid (4-hydroxy-naphthalen-1-ylmethylene)-hydrazide	Investigative	135471545	C18H15N3O2	305.3	C1=CC=C2C(=C1)C(=CC=C2O)/C=N/NC(=O)C3=CC=C(C=C3)N	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	B4F7BW	1-[4-[1-[3-(3,5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]pyrrolidine-3-carboxylic acid	Investigative	127047905	C34H29Cl2N3O4	614.5	CC(C1=CC=C(C=C1)C(=O)N2CCC(C2)C(=O)O)N3C(=CC(=N3)C4=CC(=CC(=C4)Cl)Cl)C5=CC6=C(C=C5)C=C(C=C6)OC	IC50 = 131100 nM	Poor binder
T60182	Glucagon receptor	B52NOY	Naphthalen-1-yl-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-methanone	Investigative	44411059	C23H23NO2	345.4	C1CCN(C1)CCOC2=CC=C(C=C2)C(=O)C3=CC=CC4=CC=CC=C43	IC50 = 55000 nM	Poor binder
T60182	Glucagon receptor	B5NY1P	1-(3,4-Dihydroxy-phenyl)-2-(5-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone	Investigative	654283	C16H13N3O3S	327.4	C1=CC=C(C=C1)C2=NC(=NN2)SCC(=O)C3=CC(=C(C=C3)O)O	Ki = 55000 nM	Poor binder
T60182	Glucagon receptor	B5XE1T	N'-[(E)-(4-Hydroxy-3-methoxyphenyl)methylidene]naphthalene-1-carbohydrazide	Investigative	135538097	C19H16N2O3	320.3	COC1=C(C=CC(=C1)/C=N/NC(=O)C2=CC=CC3=CC=CC=C32)O	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	B7LSX0	N-[(E)-(2,4-Dioxo-1H-pyrimidin-5-yl)methylideneamino]-4-hydroxy-3-methoxybenzamide	Investigative	135443742	C13H12N4O5	304.26	COC1=C(C=CC(=C1)C(=O)N/N=C/C2=CNC(=O)NC2=O)O	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	B91NIP	4-Hydroxy-3-methoxy-benzoic acid (1-naphthalen-1-yl-ethylidene)-hydrazide	Investigative	11809785	C20H18N2O3	334.4	C/C(=N\\NC(=O)C1=CC(=C(C=C1)O)OC)/C2=CC=CC3=CC=CC=C32	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BBO43Y	2-(1H-Benzimidazol-2-ylsulfanyl)-1-(4-hydroxyphenyl)ethanone	Investigative	677928	C15H12N2O2S	284.3	C1=CC=C2C(=C1)NC(=N2)SCC(=O)C3=CC=C(C=C3)O	Ki ~ 60000 nM	Poor binder
T60182	Glucagon receptor	BE5U6B	1-(3,4-Dihydroxyphenyl)-2-(quinoline-2-ylthio)ethanone	Investigative	10804979	C17H13NO3S	311.4	C1=CC=C2C(=C1)C=CC(=N2)SCC(=O)C3=CC(=C(C=C3)O)O	Ki = 160000 nM	Poor binder
T60182	Glucagon receptor	BEJ92S	2-(1,3-Benzothiazol-2-ylsulfanyl)-1-(3,4-dihydroxyphenyl)ethanone	Investigative	4066568	C15H11NO3S2	317.4	C1=CC=C2C(=C1)N=C(S2)SCC(=O)C3=CC(=C(C=C3)O)O	Ki = 73000 nM	Poor binder
T60182	Glucagon receptor	BEM9U8	3-Chloro-4-hydroxy-5-methoxy-benzoic acid(4-hydroxy-naphthalen-1-ylmethylene)-hydrazide	Investigative	135437141	C19H15ClN2O4	370.8	COC1=C(C(=CC(=C1)C(=O)N/N=C/C2=CC=C(C3=CC=CC=C23)O)Cl)O	IC50 = 60000 nM	Poor binder
T60182	Glucagon receptor	BF26EV	4-Hydroxy-benzoic acid N''-naphthalen-1-ylmethyl-hydrazide	Investigative	10924293	C18H16N2O2	292.3	C1=CC=C2C(=C1)C=CC=C2CNNC(=O)C3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BFZ17V	4-Hydroxy-3-methoxy-benzoic acid (4-methoxy-benzylidene)-hydrazide	Investigative	10957546	C16H16N2O4	300.31	COC1=CC=C(C=C1)/C=N/NC(=O)C2=CC(=C(C=C2)O)OC	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BK9CY7	4-Hydroxy-N-[(E)-(4-hydroxynaphthalen-1-yl)methylideneamino]-3-(morpholin-4-ylmethyl)benzamide	Investigative	135451009	C23H23N3O4	405.4	C1COCCN1CC2=C(C=CC(=C2)C(=O)N/N=C/C3=CC=C(C4=CC=CC=C34)O)O	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BKOX23	1H-Indole-5-carboxylic acid (4-hydroxy-naphthalen-1-ylmethylene)-hydrazide	Investigative	135542514	C20H15N3O2	329.4	C1=CC=C2C(=C1)C(=CC=C2O)/C=N/NC(=O)C3=CC4=C(C=C3)NC=C4	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BN7UA3	4-Hydroxy-3-methoxy-benzoic acid (5-methyl-1H-imidazol-4-ylmethylene)-hydrazide	Investigative	135470359	C13H14N4O3	274.28	CC1=C(N=CN1)/C=N/NC(=O)C2=CC(=C(C=C2)O)OC	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BN9Q1H	Quinoxaline-6-carboxylic acid (4-hydroxy-naphthalen-1-ylmethylene)-hydrazide	Investigative	135545151	C20H14N4O2	342.3	C1=CC=C2C(=C1)C(=CC=C2O)/C=N/NC(=O)C3=CC4=NC=CN=C4C=C3	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BP1TI6	1-[4-[1-[3-(3,5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]piperidine-3-carboxylic acid	Investigative	127047906	C35H31Cl2N3O4	628.5	CC(C1=CC=C(C=C1)C(=O)N2CCCC(C2)C(=O)O)N3C(=CC(=N3)C4=CC(=CC(=C4)Cl)Cl)C5=CC6=C(C=C5)C=C(C=C6)OC	IC50 = 112200 nM	Poor binder
T60182	Glucagon receptor	BPAX56	1-(3,4-Dihydroxyphenyl)-2-(5-nitro-1H-benzimidazole-2-ylthio)ethanone	Investigative	10617488	C15H11N3O5S	345.3	C1=CC(=C(C=C1C(=O)CSC2=NC3=C(N2)C=C(C=C3)[N+](=O)[O-])O)O	Ki = 55000 nM	Poor binder
T60182	Glucagon receptor	BR0A9H	6-Hydroxy-nicotinic acid (4-hydroxy-naphthalen-1-ylmethylene)-hydrazide	Investigative	135407749	C17H13N3O3	307.3	C1=CC=C2C(=C1)C(=CC=C2O)/C=N/NC(=O)C3=CNC(=O)C=C3	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BRM7L4	1-(3,4-Dihydroxyphenyl)-2-(4,5-diphenyl-1H-imidazole-2-ylthio)ethanone	Investigative	10692484	C23H18N2O3S	402.5	C1=CC=C(C=C1)C2=C(N=C(N2)SCC(=O)C3=CC(=C(C=C3)O)O)C4=CC=CC=C4	Ki = 180000 nM	Poor binder
T60182	Glucagon receptor	BRMX61	3-[[1-[3-(3,5-Dichlorophenyl)-5-(furan-2-yl)pyrazol-1-yl]-2,3-dihydro-1H-indene-5-carbonyl]amino]propanoic acid	Investigative	127047254	C26H21Cl2N3O4	510.4	C1CC2=C(C1N3C(=CC(=N3)C4=CC(=CC(=C4)Cl)Cl)C5=CC=CO5)C=CC(=C2)C(=O)NCCC(=O)O	IC50 = 71800 nM	Poor binder
T60182	Glucagon receptor	BS7N0E	5-Hydroxy-1H-indole-2-carboxylic acid (4-hydroxy-naphthalen-1-ylmethylene)-hydrazide	Investigative	135427275	C20H15N3O3	345.4	C1=CC=C2C(=C1)C(=CC=C2O)/C=N/NC(=O)C3=CC4=C(N3)C=CC(=C4)O	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BUQ30M	3-Chloro-N-[(E)-1-[3,5-dimethoxy-4-[(4-propan-2-ylphenyl)methoxy]phenyl]ethylideneamino]-4-hydroxybenzamide	Investigative	44373520	C27H29ClN2O5	497	CC(C)C1=CC=C(C=C1)COC2=C(C=C(C=C2OC)/C(=N/NC(=O)C3=CC(=C(C=C3)O)Cl)/C)OC	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BX2Z0K	4-Hydroxy-3-methoxy-benzoic acid (4-styryl-benzylidene)-hydrazide	Investigative	10981564	C23H20N2O3	372.4	COC1=C(C=CC(=C1)C(=O)N/N=C/C2=CC=C(C=C2)/C=C/C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T60182	Glucagon receptor	BZ7Y6T	3-[[[2-[2-(3,4-Dihydroxyphenyl)-2-oxoethylthio]-1H-benzimidazole-5-yl]oxy]methyl]benzoic acid	Investigative	10694841	C23H18N2O6S	450.5	C1=CC(=CC(=C1)C(=O)O)COC2=CC3=C(C=C2)N=C(N3)SCC(=O)C4=CC(=C(C=C4)O)O	Ki = 95000 nM	Poor binder