TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T60857	Dihydrodiol dehydrogenase type I	D0N9DS	PMID27607364-Compound-4	Patented	3016	C16H13ClN2O	284.74	CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3	IC50 = 84000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	B37ZTK	Chembl4166474	Investigative	145952913	C10H6F3N3O2S	289.24	C1=CC(=CC(=C1)NC(=O)C2=NSNC2=O)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	B4DI6L	(E)-2,3-Bis(4-methylsulfonylphenyl)prop-2-enoic acid	Investigative	71718851	C17H16O6S2	380.4	CS(=O)(=O)C1=CC=C(C=C1)/C=C(\\C2=CC=C(C=C2)S(=O)(=O)C)/C(=O)O	IC50 = 51000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	B6CU7T	5-{[(2,5-Dimethyl-3-furyl)carbonyl]amino}-2-hydroxybenzoic acid	Investigative	703764	C14H13NO5	275.26	CC1=CC(=C(O1)C)C(=O)NC2=CC(=C(C=C2)O)C(=O)O	Ki = 118000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	B72JOP	2-(9-Chloro-1h-Phenanthro[9,10-D]imidazol-2-Yl)benzene-1,3-Dicarbonitrile	Investigative	16070041	C23H11ClN4	378.8	C1=CC=C2C(=C1)C3=C(C=CC(=C3)Cl)C4=C2N=C(N4)C5=C(C=CC=C5C#N)C#N	IC50 ~ 50000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	B7V1PO	(E)-2-(3-Chlorophenyl)-3-(4-methylsulfonylphenyl)prop-2-enoic acid	Investigative	71654029	C16H13ClO4S	336.8	CS(=O)(=O)C1=CC=C(C=C1)/C=C(\\C2=CC(=CC=C2)Cl)/C(=O)O	IC50 = 76700 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	B8HZ2B	(E)-3-(3,4-Dimethoxyphenyl)-2-naphthalen-1-ylprop-2-enoic acid	Investigative	71720050	C21H18O4	334.4	COC1=C(C=C(C=C1)/C=C(\\C2=CC=CC3=CC=CC=C32)/C(=O)O)OC	IC50 = 127800 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	B8VKS6	4-[Methyl(phenylsulfonyl)amino]benzoic acid	Investigative	804306	C14H13NO4S	291.32	CN(C1=CC=C(C=C1)C(=O)O)S(=O)(=O)C2=CC=CC=C2	Ki = 148000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	B9OS0A	(E)-3-(4-Methylsulfonylphenyl)-2-phenylprop-2-enoic acid	Investigative	44451451	C16H14O4S	302.3	CS(=O)(=O)C1=CC=C(C=C1)/C=C(\\C2=CC=CC=C2)/C(=O)O	IC50 = 139200 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	B9TR1O	7-Benzoyl-4,5-dihydro-1,4-benzoxazepin-3(2H)-one	Investigative	668656	C16H13NO3	267.28	C1C2=C(C=CC(=C2)C(=O)C3=CC=CC=C3)OCC(=O)N1	Ki = 76000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BA8YB6	5-{[(4,5-Dimethyl-2-furyl)carbonyl]amino}-2-hydroxybenzoic acid	Investigative	579839	C14H13NO5	275.26	CC1=C(OC(=C1)C(=O)NC2=CC(=C(C=C2)O)C(=O)O)C	Ki = 82000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BB53JG	4-Methoxybenzophenone	Investigative	69146	C14H12O2	212.24	COC1=CC=C(C=C1)C(=O)C2=CC=CC=C2	IC50 = 180000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BCS78J	2-Benzoylbenzoic acid	Investigative	6813	C14H10O3	226.23	C1=CC=C(C=C1)C(=O)C2=CC=CC=C2C(=O)O	IC50 = 70000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BD04KM	Jasmonic acid	Investigative	5281166	C12H18O3	210.27	CC/C=C\\C[C@@H]1[C@H](CCC1=O)CC(=O)O	Ki = 162000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BE4U2W	Chembl4173733	Investigative	145951864	C11H9F3N4O2	286.21	CN1NC(=O)C(=N1)C(=O)NC2=CC=CC(=C2)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BFIM80	3-{[(4-Methylphenyl)sulfonyl]amino}benzoic acid	Investigative	285710	C14H13NO4S	291.32	CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)C(=O)O	Ki = 111000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BG8E6V	2-[(3-Methyl-1H-pyrazol-1-yl)methyl]quinoline-4-carboxylic acid	Investigative	19585911	C15H13N3O2	267.28	CC1=NN(C=C1)CC2=NC3=CC=CC=C3C(=C2)C(=O)O	Ki = 117000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BGQ2K9	3-(Phenacylamino)benzoic acid	Investigative	591357	C15H13NO3	255.27	C1=CC=C(C=C1)C(=O)CNC2=CC=CC(=C2)C(=O)O	Ki = 72000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BH0S4T	2-(3-Hydroxyphenyl)quinoline-4-carboxylic acid	Investigative	673729	C16H11NO3	265.26	C1=CC=C2C(=C1)C(=CC(=N2)C3=CC(=CC=C3)O)C(=O)O	Ki = 54000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BI57NH	N-[(6-Oxo-1H-pyrimidin-4-yl)methyl]pyrazolo[1,5-a]pyridine-2-carboxamide	Investigative	136236285	C13H11N5O2	269.26	C1=CC2=CC(=NN2C=C1)C(=O)NCC3=CC(=O)NC=N3	Ki = 118000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BJFQ57	Chembl4170286	Investigative	145954680	C14H13F3N4O2	326.27	C1CC1CN2NC(=O)C(=N2)C(=O)NC3=CC=CC(=C3)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BK82CX	3-[(2,6-Dimethylpyrimidin-4-yl)amino]-4-methylbenzoic acid	Investigative	16876789	C14H15N3O2	257.29	CC1=C(C=C(C=C1)C(=O)O)NC2=NC(=NC(=C2)C)C	Ki = 144000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BKCV12	5-Methoxy-2-methyl-3-indoleacetic acid	Investigative	76151	C12H13NO3	219.24	CC1=C(C2=C(N1)C=CC(=C2)OC)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BKTJ12	N-[4-[Cyano(phenyl)methyl]phenyl]acetamide	Investigative	2832029	C16H14N2O	250.29	CC(=O)NC1=CC=C(C=C1)C(C#N)C2=CC=CC=C2	Ki = 87000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BLHG59	(E)-2-(4-Methylsulfonylphenyl)-3-phenylprop-2-enoic acid	Investigative	53326266	C16H14O4S	302.3	CS(=O)(=O)C1=CC=C(C=C1)/C(=C\\C2=CC=CC=C2)/C(=O)O	IC50 = 69800 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BP32VS	(E)-2-(4-Chlorophenyl)-3-(4-methylsulfonylphenyl)prop-2-enoic acid	Investigative	71654026	C16H13ClO4S	336.8	CS(=O)(=O)C1=CC=C(C=C1)/C=C(\\C2=CC=C(C=C2)Cl)/C(=O)O	IC50 = 86600 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BQ5NU0	(E)-3-(3-Hydroxy-4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)prop-2-enoic acid	Investigative	5315107	C19H20O7	360.4	COC1=C(C=C(C=C1)/C=C(\\C2=CC(=C(C(=C2)OC)OC)OC)/C(=O)O)O	IC50 = 121100 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BVQZ97	3-(1H-Benzimidazol-2-ylamino)benzoic acid	Investigative	1081072	C14H11N3O2	253.26	C1=CC=C2C(=C1)NC(=N2)NC3=CC=CC(=C3)C(=O)O	Ki = 142000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BX51GZ	3-[(2-Naphthylsulfonyl)amino]propanoic acid	Investigative	362740	C13H13NO4S	279.31	C1=CC=C2C=C(C=CC2=C1)S(=O)(=O)NCCC(=O)O	Ki = 148000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	BZ4KV5	Chembl4177097	Investigative	145971744	C10H6F3N3O3	273.17	C1=CC(=CC(=C1)NC(=O)C2=NONC2=O)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T60857	Dihydrodiol dehydrogenase type I	D06SPO	3,5-dichlorosalicylic acid	Investigative	9445	C7H4Cl2O3	207.01	C1=C(C=C(C(=C1C(=O)O)O)Cl)Cl	Ki = 94000 nM	Poor binder