TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T61722	Prostaglandin D2 receptor 2	B0E3DK	3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-2-methyl-propionic acid	Investigative	44390350	C22H23FN2O4S	430.5	CC(CN1C2=C(CCCC2)C3=C1C=CC(=C3)NS(=O)(=O)C4=CC=C(C=C4)F)C(=O)O	Ki ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B0EKN8	[2-(3'-Cyano-biphenyl-2-ylmethyl)-4-(4-fluoro-phenyl)-thiazol-5-yl]-acetic acid	Investigative	46229807	C25H17FN2O2S	428.5	C1=CC=C(C(=C1)CC2=NC(=C(S2)CC(=O)O)C3=CC=C(C=C3)F)C4=CC=CC(=C4)C#N	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B0L7AB	3-[6-(Propane-1-sulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-propionic acid	Investigative	44390331	C18H24N2O4S	364.5	CCCS(=O)(=O)NC1=CC2=C(C=C1)N(C3=C2CCCC3)CCC(=O)O	Ki ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B0OI3A	2-(4-(4-Chlorophenyl)-2-((6-chloropyridin-2-yl)(phenyl)methyl)thiazol-5-yl)acetic acid	Investigative	46230225	C23H16Cl2N2O2S	455.4	C1=CC=C(C=C1)C(C2=NC(=CC=C2)Cl)C3=NC(=C(S3)CC(=O)O)C4=CC=C(C=C4)Cl	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B0R3BG	2-(2-(Bis(4-fluorophenyl)methyl)-4-(2-(pyrrolidin-1-yl)pyridin-4-yl)thiazol-5-yl)acetic acid	Investigative	46229943	C27H23F2N3O2S	491.6	C1CCN(C1)C2=NC=CC(=C2)C3=C(SC(=N3)C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B0U7SC	2-(4-(4-Chlorophenyl)-2-(1-phenylpropyl)thiazol-5-yl)acetic acid	Investigative	46229937	C20H18ClNO2S	371.9	CCC(C1=CC=CC=C1)C2=NC(=C(S2)CC(=O)O)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B1ZG6D	2-(2-(2-Fluorophenylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid	Investigative	1001787	C23H17FN2O3S	420.5	C1=CC=C(C=C1)OC2=CC=C(C=C2)C3=C(SC(=N3)NC4=CC=CC=C4F)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B2G5LV	2-(2-(2-Bromobenzyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid	Investigative	46229761	C18H13BrFNO2S	406.3	C1=CC=C(C(=C1)CC2=NC(=C(S2)CC(=O)O)C3=CC=C(C=C3)F)Br	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B2ZU3P	4-Anilino-1-benzoyl-2-methyl-1,2,3,4-tetrahydroquinoline	Investigative	570211	C23H22N2O	342.4	CC1CC(C2=CC=CC=C2N1C(=O)C3=CC=CC=C3)NC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B5QB7R	2-[2-[2-[[(4S,5R)-4-Methyl-2-oxo-5-phenyl-1,3-oxazolidin-3-yl]methyl]-4-(trifluoromethyl)phenyl]phenyl]acetic acid	Investigative	57401720	C26H22F3NO4	469.5	C[C@H]1[C@H](OC(=O)N1CC2=C(C=CC(=C2)C(F)(F)F)C3=CC=CC=C3CC(=O)O)C4=CC=CC=C4	IC50 = 62000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B5V2NO	3-[3-[2-[[(4S,5R)-4-Methyl-2-oxo-5-phenyl-1,3-oxazolidin-3-yl]methyl]-4-(trifluoromethyl)phenyl]phenyl]propanoic acid	Investigative	57398275	C27H24F3NO4	483.5	C[C@H]1[C@H](OC(=O)N1CC2=C(C=CC(=C2)C(F)(F)F)C3=CC=CC(=C3)CCC(=O)O)C4=CC=CC=C4	IC50 = 75000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B5YZK6	2-(2-(2-Chlorophenylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid	Investigative	3145335	C23H17ClN2O3S	436.9	C1=CC=C(C=C1)OC2=CC=C(C=C2)C3=C(SC(=N3)NC4=CC=CC=C4Cl)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B6IED4	{2-[(E)-{2-[(3-Methyl-1H-pyrazol-5-yl)carbonyl]hydrazinylidene}methyl]phenoxy}acetic acid	Investigative	5344298	C14H14N4O4	302.29	CC1=CC(=NN1)C(=O)N/N=C/C2=CC=CC=C2OCC(=O)O	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B6PH1R	(2-{(E)-[2-(1H-Benzimidazol-1-ylacetyl)hydrazinylidene]methyl}phenoxy)acetic acid	Investigative	5726103	C18H16N4O4	352.3	C1=CC=C(C(=C1)/C=N/NC(=O)CN2C=NC3=CC=CC=C32)OCC(=O)O	IC50 = 81700 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B8OCP5	3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-butyric acid	Investigative	44390333	C22H23FN2O4S	430.5	CC(CC(=O)O)N1C2=C(CCCC2)C3=C1C=CC(=C3)NS(=O)(=O)C4=CC=C(C=C4)F	Ki ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B9XH3F	2-Amino-4-(4-chlorophenyl)thiazole-5-acetic acid	Investigative	198256	C11H9ClN2O2S	268.72	C1=CC(=CC=C1C2=C(SC(=N2)N)CC(=O)O)Cl	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	B9ZCQ4	2-(2-(Bis(4-fluorophenyl)methyl)-4-(2-(dimethylamino)pyridin-4-yl)thiazol-5-yl)acetic acid	Investigative	46229941	C25H21F2N3O2S	465.5	CN(C)C1=NC=CC(=C1)C2=C(SC(=N2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BA31TL	2-(5-Methyl-6-(4-(methylsulfonyl)phenylsulfonyl)-6H-thieno[2,3-b]pyrrol-4-yl)acetic acid	Investigative	44188793	C16H15NO6S3	413.5	CC1=C(C2=C(N1S(=O)(=O)C3=CC=C(C=C3)S(=O)(=O)C)SC=C2)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BAOC60	3-[6-(Toluene-2-sulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-propionic acid	Investigative	44390342	C22H24N2O4S	412.5	CC1=CC=CC=C1S(=O)(=O)NC2=CC3=C(C=C2)N(C4=C3CCCC4)CCC(=O)O	Ki ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BB2A0Y	(+/-)-N-(2-Methyl-1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylacetamide	Investigative	46879283	C24H24N2O3S	420.5	CC1CC(C2=CC=CC=C2N1S(=O)(=O)C3=CC=CC=C3)N(C4=CC=CC=C4)C(=O)C	IC50 = 62000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BBO49F	{2-[({[(4-Methylphenyl)amino]acetyl}hydrazono)methyl]phenoxy}acetic acid	Investigative	5722969	C18H19N3O4	341.4	CC1=CC=C(C=C1)NCC(=O)N/N=C/C2=CC=CC=C2OCC(=O)O	IC50 = 60200 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BC0DU1	2-(4-(2-(Azetidin-1-yl)pyridin-4-yl)-2-(bis(4-fluorophenyl)methyl)thiazol-5-yl)acetic acid	Investigative	46229942	C26H21F2N3O2S	477.5	C1CN(C1)C2=NC=CC(=C2)C3=C(SC(=N3)C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BC4T5I	2-(4-(6-Amino-5-methylpyridin-3-yl)-2-(bis(4-fluorophenyl)methyl)thiazol-5-yl)acetic acid	Investigative	46229993	C24H19F2N3O2S	451.5	CC1=CC(=CN=C1N)C2=C(SC(=N2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BCZI07	3-[6-(3-Phenyl-ureido)-1,2,3,4-tetrahydro-carbazol-9-yl]-propionic acid	Investigative	44390348	C22H23N3O3	377.4	C1CCC2=C(C1)C3=C(N2CCC(=O)O)C=CC(=C3)NC(=O)NC4=CC=CC=C4	Ki ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BDW75C	2-(4-(2-(4-Acetylpiperazin-1-yl)pyridin-4-yl)-2-(bis(4-fluorophenyl)methyl)thiazol-5-yl)acetic acid	Investigative	46229991	C29H26F2N4O3S	548.6	CC(=O)N1CCN(CC1)C2=NC=CC(=C2)C3=C(SC(=N3)C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BE09VQ	N-(2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylacetamide	Investigative	2837129	C18H20N2O	280.4	CC1CC(C2=CC=CC=C2N1)N(C3=CC=CC=C3)C(=O)C	IC50 ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BF40ZJ	2-(4-(4-Chlorophenyl)-2-(4-phenylpiperidin-4-yl)thiazol-5-yl)acetic acid	Investigative	46229938	C22H21ClN2O2S	412.9	C1CNCCC1(C2=CC=CC=C2)C3=NC(=C(S3)CC(=O)O)C4=CC=C(C=C4)Cl	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BJNH72	2-(2-Benzhydryl-4-(5-chloro-2-methoxyphenyl)thiazol-5-yl)acetic acid	Investigative	46230284	C25H20ClNO3S	449.9	COC1=C(C=C(C=C1)Cl)C2=C(SC(=N2)C(C3=CC=CC=C3)C4=CC=CC=C4)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BK1R5L	[4-(4-Fluoro-phenyl)-2-(2'-methoxy-biphenyl-2-ylmethyl)-thiazol-5-yl]-acetic acid	Investigative	46229853	C25H20FNO3S	433.5	COC1=CC=CC=C1C2=CC=CC=C2CC3=NC(=C(S3)CC(=O)O)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BKXT04	{2-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-ethyl}-phosphonic acid	Investigative	44390311	C20H22FN2O5PS	452.4	C1CCC2=C(C1)C3=C(N2CCP(=O)(O)O)C=CC(=C3)NS(=O)(=O)C4=CC=C(C=C4)F	Ki ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BL16PG	4-(2-(2,4-Dichlorophenylsulfonamido)-4-(ethylcarbamoyl)phenoxy)-3-methoxybenzoic acid	Investigative	45486045	C23H20Cl2N2O7S	539.4	CCNC(=O)C1=CC(=C(C=C1)OC2=C(C=C(C=C2)C(=O)O)OC)NS(=O)(=O)C3=C(C=C(C=C3)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BL92OS	3-(6-Amino-1,2,3,4-tetrahydro-carbazol-9-yl)-propionic acid	Investigative	44390288	C15H18N2O2	258.32	C1CCC2=C(C1)C3=C(N2CCC(=O)O)C=CC(=C3)N	Ki ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BMX36L	[4-(4-Fluoro-phenyl)-2-(3'-trifluoromethoxy-biphenyl-2-ylmethyl)-thiazol-5-yl]-acetic acid	Investigative	46229854	C25H17F4NO3S	487.5	C1=CC=C(C(=C1)CC2=NC(=C(S2)CC(=O)O)C3=CC=C(C=C3)F)C4=CC(=CC=C4)OC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BN1LI5	2-(4-(4-Chlorophenyl)-2-(cyclohexyl(phenyl)methyl)thiazol-5-yl)acetic acid	Investigative	46230147	C24H24ClNO2S	426	C1CCC(CC1)C(C2=CC=CC=C2)C3=NC(=C(S3)CC(=O)O)C4=CC=C(C=C4)Cl	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BP59XR	2-(2-Benzhydryl-4-(4-(trifluoromethyl)phenyl)thiazol-5-yl)acetic acid	Investigative	46230283	C25H18F3NO2S	453.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=NC(=C(S3)CC(=O)O)C4=CC=C(C=C4)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BPBC30	3-(6-Benzoylamino-1,2,3,4-tetrahydro-carbazol-9-yl)-propionic acid	Investigative	44390269	C22H22N2O3	362.4	C1CCC2=C(C1)C3=C(N2CCC(=O)O)C=CC(=C3)NC(=O)C4=CC=CC=C4	Ki ~ 50000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BRK16A	2-(2-(Bis(4-fluorophenyl)methyl)-4-(4-sulfamoylphenyl)thiazol-5-yl)acetic acid	Investigative	46230512	C24H18F2N2O4S2	500.5	C1=CC(=CC=C1C2=C(SC(=N2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)CC(=O)O)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BTV37R	3-[2-[[(4S,5R)-4-Methyl-2-oxo-5-phenyl-1,3-oxazolidin-3-yl]methyl]-4-(trifluoromethyl)phenyl]benzoic acid	Investigative	57401719	C25H20F3NO4	455.4	C[C@H]1[C@H](OC(=O)N1CC2=C(C=CC(=C2)C(F)(F)F)C3=CC(=CC=C3)C(=O)O)C4=CC=CC=C4	IC50 = 91000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BWQ6X2	2-(4-(4-Chlorophenyl)-2-(2-phenoxybenzyl)thiazol-5-yl)acetic acid	Investigative	46229890	C24H18ClNO3S	435.9	C1=CC=C(C=C1)OC2=CC=CC=C2CC3=NC(=C(S3)CC(=O)O)C4=CC=C(C=C4)Cl	IC50 ~ 100000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BXC50J	2-[(7R)-7-[(4-Fluorophenyl)sulfonyl-methylamino]-6,7,8,9-tetrahydropyrido[2,3-b]indolizin-10-yl]acetic acid	Investigative	45273637	C20H20FN3O4S	417.5	CN([C@@H]1CCC2=C(C3=C(N2C1)C=CC=N3)CC(=O)O)S(=O)(=O)C4=CC=C(C=C4)F	IC50 = 51000 nM	Poor binder
T61722	Prostaglandin D2 receptor 2	BXJC86	2-(2-Benzhydryl-4-(2,5-dimethoxyphenyl)thiazol-5-yl)acetic acid	Investigative	46230331	C26H23NO4S	445.5	COC1=CC(=C(C=C1)OC)C2=C(SC(=N2)C(C3=CC=CC=C3)C4=CC=CC=C4)CC(=O)O	IC50 ~ 100000 nM	Poor binder